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Recurrent

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Recurrent - Free Register to Access Experts & Abstracts

Jun Wang - One of the best experts on this subject based on the ideXlab platform.

Guang Wu - One of the best experts on this subject based on the ideXlab platform.

Benjamin T. Galen - One of the best experts on this subject based on the ideXlab platform.

  • Recurrent Meningitis
    Current Pain and Headache Reports, 2017
    Co-Authors: Jon Rosenberg, Benjamin T. Galen
    Abstract:

    Purpose of Review Recurrent meningitis is a rare clinical scenario that can be self-limiting or life threatening depending on the underlying etiology. This review describes the causes, risk factors, treatment, and prognosis for Recurrent meningitis. As a general overview of a broad topic, the aim of this review is to provide clinicians with a comprehensive differential diagnosis to aide in the evaluation and management of a patient with Recurrent meningitis. Recent Findings New developments related to understanding the pathophysiology of Recurrent meningitis are as scarce as studies evaluating the treatment and prevention of this rare disorder. A trial evaluating oral valacyclovir suppression after HSV-2 meningitis did not demonstrate a benefit in preventing recurrences. The data on prophylactic antibiotics after basilar skull fractures do not support their use. Intrathecal trastuzumab has shown promise in treating leptomeningeal carcinomatosis from HER-2 positive breast cancer. Monoclonal antibodies used to treat cancer and autoimmune diseases are new potential causes of drug-induced aseptic meningitis. Summary Despite their potential for causing Recurrent meningitis, the clinical entities reviewed herein are not frequently discussed together given that they are a heterogeneous collection of unrelated, rare diseases. Epidemiologic data on Recurrent meningitis are lacking. The syndrome of Recurrent benign lymphocytic meningitis described by Mollaret in 1944 was later found to be closely related to HSV-2 reactivation, but HSV-2 is by no means the only etiology of Recurrent aseptic meningitis. While the mainstay of treatment for Recurrent meningitis is supportive care, it is paramount to ensure that reversible and treatable causes have been addressed for further prevention.

  • Recurrent Meningitis.
    Current pain and headache reports, 2017
    Co-Authors: Jon Rosenberg, Benjamin T. Galen
    Abstract:

    Recurrent meningitis is a rare clinical scenario that can be self-limiting or life threatening depending on the underlying etiology. This review describes the causes, risk factors, treatment, and prognosis for Recurrent meningitis. As a general overview of a broad topic, the aim of this review is to provide clinicians with a comprehensive differential diagnosis to aide in the evaluation and management of a patient with Recurrent meningitis. New developments related to understanding the pathophysiology of Recurrent meningitis are as scarce as studies evaluating the treatment and prevention of this rare disorder. A trial evaluating oral valacyclovir suppression after HSV-2 meningitis did not demonstrate a benefit in preventing recurrences. The data on prophylactic antibiotics after basilar skull fractures do not support their use. Intrathecal trastuzumab has shown promise in treating leptomeningeal carcinomatosis from HER-2 positive breast cancer. Monoclonal antibodies used to treat cancer and autoimmune diseases are new potential causes of drug-induced aseptic meningitis. Despite their potential for causing Recurrent meningitis, the clinical entities reviewed herein are not frequently discussed together given that they are a heterogeneous collection of unrelated, rare diseases. Epidemiologic data on Recurrent meningitis are lacking. The syndrome of Recurrent benign lymphocytic meningitis described by Mollaret in 1944 was later found to be closely related to HSV-2 reactivation, but HSV-2 is by no means the only etiology of Recurrent aseptic meningitis. While the mainstay of treatment for Recurrent meningitis is supportive care, it is paramount to ensure that reversible and treatable causes have been addressed for further prevention.

Tuomas Jartti - One of the best experts on this subject based on the ideXlab platform.

  • prednisolone reduces Recurrent wheezing after a first wheezing episode associated with rhinovirus infection or eczema
    The Journal of Allergy and Clinical Immunology, 2007
    Co-Authors: Pasi Lehtinen, Timo Vanto, Aino Ruohola, Tytti Vuorinen, Olli Ruuskanen, Tuomas Jartti
    Abstract:

    Background Rhinovirus-induced early wheezing has been suggested as a new important risk factor for Recurrent wheezing. Objective We sought to investigate the risk factors for Recurrent wheezing and to determine post hoc the efficacy of prednisolone in risk groups. Methods We followed for 1 year 118 children (median age, 1.1 years) who had had their first episode of wheezing and had participated in a trial comparing prednisolone with placebo in hospitalized children. Demographics and laboratory data were obtained at study entry. The follow-up outcome was Recurrent wheezing (3 physician-confirmed episodes). Results Recurrent wheezing was diagnosed in 44 (37%) children. Independent risk factors were age P = .007 for interaction). Prednisolone was associated with less Recurrent wheezing in the rhinovirus group (0.19; 95% CI, 0.05-0.71), but not in the RSV (2.12; 95% CI, 0.46-9.76) or in the RSV/rhinovirus-negative groups (2.03; 95% CI, 0.83-5.00; P = .017 for interaction). Conclusion Rhinovirus-induced early wheezing is a major viral risk factor for Recurrent wheezing. Prednisolone may prevent Recurrent wheezing in rhinovirus-affected first-time wheezers. The presence of eczema may also influence the response to prednisolone. Clinical implications A prospective trial is needed to test the hypothesis that prednisolone reduces Recurrent wheezing in rhinovirus-affected wheezing children.

Yongan Zhou - One of the best experts on this subject based on the ideXlab platform.

  • Intraoperative Recurrent laryngeal nerve monitoring: a useful method for patients with esophageal cancer
    Diseases of The Esophagus, 2012
    Co-Authors: Daixing Zhong, Jinbo Zhao, Lianhong Chen, Yongan Zhou, Yu Hong Li, Yunjie Wang, Qingshu Cheng, Weiping Zhou, Xia Li
    Abstract:

    Summary It is well accepted that Recurrent laryngeal nerve paralysis is a severe complication of esophagectomy or lymphadenectomy performed adjacent to the Recurrent laryngeal nerves. Herein, determination of the effectiveness of implementing continuous Recurrent laryngeal nerve monitoring to reduce the incidence of Recurrent laryngeal nerve paralysis after esophagectomy was sought. A total of 115 patients diagnosed with esophageal cancer were enrolled in the thoracic section of the Tangdu Hospital of the Fourth Military Medical University from April 2008 to April 2009. Clinical parameters of patients, the morbidity, and the mortality following esophageal resection were recorded and compared. After the surgery, a 2-year follow up was completed. It was found that Recurrent laryngeal nerve paralysis and postoperative pneumonia were more frequently diagnosed in the patients that did not receive continuous Recurrent laryngeal nerve monitoring (6/61 vs. 0/54). Furthermore, positive mediastinal lymph nodes (P = 0.015), total mediastinal lymph nodes (P < 0.001), positive total lymph nodes (P = 0.027), and total lymph nodes (P < 0.001) were more often surgically removed in the patients with continuous Recurrent laryngeal nerve monitoring. These patients also had a higher 2-year survival rate (P = 0.038) after surgery. It was concluded that continuous intraoperative Recurrent laryngeal nerve monitoring is technically safe and effectively identifies the Recurrent laryngeal nerves. This may be a helpful method for decreasing the incidence of Recurrent laryngeal nerve paralysis and postoperative pneumonia, and for improving the efficiency of lymphadenectomy.

  • Intraoperative Recurrent laryngeal nerve monitoring during surgery for left lung cancer
    The Journal of Thoracic and Cardiovascular Surgery, 2010
    Co-Authors: Jinbo Zhao, Wenhai Li, Lianhong Chen, Daixing Zhong, Hui Xu, Yongan Zhou
    Abstract:

    Objective This study evaluated the safety and efficacy of intraoperative Recurrent laryngeal nerve monitoring during surgery for left lung cancer. Methods From April 2008 to April 2009, a total of 25 patients at high risk for left Recurrent laryngeal nerve injury agreed to and underwent intraoperative Recurrent laryngeal nerve monitoring during surgery for left lung cancer in our hospital. Results and clinical records were reviewed. Results All the patients' left Recurrent laryngeal nerves were identified during operation by intraoperative Recurrent laryngeal nerve monitoring. Twenty-four patients retained normal left Recurrent laryngeal nerves after the operation. One patient, in whom part of the left Recurrent laryngeal nerve was found to be invaded, underwent single-stage nerve anastomosis under Recurrent laryngeal nerve monitoring after the invaded nerve was resected. There were no significant intraoperative or postoperative complications among the other patients. Conclusions Intraoperative Recurrent laryngeal nerve monitoring during thoracotomy is a safe and effective way of identifying the nerve. It may help surgeons to avoid injuring the Recurrent laryngeal nerve during some thoracic procedures.