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11 Hydroxycorticosteroid

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B L Furman – One of the best experts on this subject based on the ideXlab platform.

  • Effects of levodopa and dopamine on plasma 11Hydroxycorticosteroid concentrations in mice.
    Hormone and Metabolic Research, 2008
    Co-Authors: Suzan A. Darwish, B L Furman
    Abstract:

    : The effects of levodopa on the plasma concentration of 11Hydroxycorticosteroids and glucose were examined in mice. In fasted, nialamide treated mice, but not in fed mice, levodopa produced a significant decrease in the plasma concentration of 11Hydroxycorticosteroids. This was accompanied by a significant and marked decrease in the plasma glucose concentration. These effects of levodopa could be mimicked by relatively small doses of dopamine injected intracerebroventricularly but not intravenously. The integrity of the hypothalamic-pituitary adrenal axis in nialamide-treated mice was suggested by the elevation in plasma 11Hydroxycorticosteroids produced by fasting or by insulin induced hypoglycaemia. These results indicate that in the mouse, as in other species, levodopa can inhibit stress provoked increases in the secretion of 11Hydroxycorticosteroids.

Margaret C. K. Browning – One of the best experts on this subject based on the ideXlab platform.

  • Plasma 11Hydroxycorticosteroid concentrations and prognosis in accidental hypothermia.
    Resuscitation, 2004
    Co-Authors: D Maclean, Margaret C. K. Browning
    Abstract:

    Abstract In 84 patients with accidental hypohypothermia plasma 11Hydroxycorticosteroid concentrations were found to be high (mean ± 1 SD=68.2 ± 44.9 μg/ 100 ml) at the time of their admission to hospital, although significant inverse correlations could still be demonstrated between the plasma 11Hydroxycorticosteroid concentrations and the severity ( P 0.0125) and estimated duration ( P

Suzan A. Darwish – One of the best experts on this subject based on the ideXlab platform.

  • Effects of levodopa and dopamine on plasma 11Hydroxycorticosteroid concentrations in mice.
    Hormone and Metabolic Research, 2008
    Co-Authors: Suzan A. Darwish, B L Furman
    Abstract:

    : The effects of levodopa on the plasma concentration of 11Hydroxycorticosteroids and glucose were examined in mice. In fasted, nialamide treated mice, but not in fed mice, levodopa produced a significant decrease in the plasma concentration of 11Hydroxycorticosteroids. This was accompanied by a significant and marked decrease in the plasma glucose concentration. These effects of levodopa could be mimicked by relatively small doses of dopamine injected intracerebroventricularly but not intravenously. The integrity of the hypothalamic-pituitary adrenal axis in nialamide-treated mice was suggested by the elevation in plasma 11Hydroxycorticosteroids produced by fasting or by insulin induced hypoglycaemia. These results indicate that in the mouse, as in other species, levodopa can inhibit stress provoked increases in the secretion of 11Hydroxycorticosteroids.