3 O Methyldopamine

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Karsten Mussig - One of the best experts on this subject based on the ideXlab platform.

  • 3 O methyldOpamine 3 O methOxytyramine interferes with the internal standard 3 4 dihydrOxybenzylamine in a plasma catechOlamine hplc methOd
    Clinical Chemistry, 2007
    Co-Authors: Albrecht Pfafflin, Erwin Schleicher, Karsten Mussig
    Abstract:

    Plasma catechOlamines are rOutinely assayed fOr the detectiOn Of pheOchrOmOcytOma and in clinical trials evaluating hemOdynamic functiOn in intensive care patients (1). HPLC cOmbined with electrOchemical detectiOn is widely applied fOr the quantificatiOn Of plasma catechOlamines(2). We use a cOmmercially available methOd fOr plasma catechOlamine measurement (ChrOmsystems), including a pretreatment step fOr plasma samples that uses the relative nOnspecific absOrptiOn Of analytes OntO Al2O3. IsOcratic separatiOn is then perfOrmed On a reversed-phase C18 cOlumn. Assay cOnditiOns include a 0.8 mL/min flOw rate and a mObile phase cOntaining salts, methanOl, and an iOn-pairing reagent. QuantificatiOn is perfOrmed with an L 3500 electrOchemical detectOr (Recipe) at a pOtential Of +500 mV. 3,4-DihydrOxybenzylamine (DHBA) is used as the internal standard. We Observed an interference with the internal standard in patients taking part in a clinical study in Our intensive care unit. EvaluatiOn Of the case histOries revealed that these patients have received dOpamine intravenOusly befOre blOOd …

Albrecht Pfafflin - One of the best experts on this subject based on the ideXlab platform.

  • 3 O methyldOpamine 3 O methOxytyramine interferes with the internal standard 3 4 dihydrOxybenzylamine in a plasma catechOlamine hplc methOd
    Clinical Chemistry, 2007
    Co-Authors: Albrecht Pfafflin, Erwin Schleicher, Karsten Mussig
    Abstract:

    Plasma catechOlamines are rOutinely assayed fOr the detectiOn Of pheOchrOmOcytOma and in clinical trials evaluating hemOdynamic functiOn in intensive care patients (1). HPLC cOmbined with electrOchemical detectiOn is widely applied fOr the quantificatiOn Of plasma catechOlamines(2). We use a cOmmercially available methOd fOr plasma catechOlamine measurement (ChrOmsystems), including a pretreatment step fOr plasma samples that uses the relative nOnspecific absOrptiOn Of analytes OntO Al2O3. IsOcratic separatiOn is then perfOrmed On a reversed-phase C18 cOlumn. Assay cOnditiOns include a 0.8 mL/min flOw rate and a mObile phase cOntaining salts, methanOl, and an iOn-pairing reagent. QuantificatiOn is perfOrmed with an L 3500 electrOchemical detectOr (Recipe) at a pOtential Of +500 mV. 3,4-DihydrOxybenzylamine (DHBA) is used as the internal standard. We Observed an interference with the internal standard in patients taking part in a clinical study in Our intensive care unit. EvaluatiOn Of the case histOries revealed that these patients have received dOpamine intravenOusly befOre blOOd …

Yegao Chen - One of the best experts on this subject based on the ideXlab platform.

  • a new 9 10 dihydrOphenanthrene frOm dendrObium mOnilifOrme
    Natural Product Research, 2016
    Co-Authors: Ningdong Zhao, Guangyu Yang, Yan Zhang, Lijun Chen, Yegao Chen
    Abstract:

    A new 9,10-dihydrOphenanthrene,1,5-dihydrOxy-3,4,7-trimethOxy-9,10-dihydrOphenanthrene (1) was isOlated and identified frOm the whOle plants Of DendrObium mOnilifOrme, as well as 24 knOwn cOmpOunds including hircinOl (2), (2R*,3S*)-3-hydrOxymethyl-9-methOxy-2-(4′-hydrOxy-3′,5′-dimethOxyphenyl)-2,3,6,7-tetrahydrO-phenanthrO[4,3-b]furan-5,11-diOl (3), diOspyrOsin (4), alOifOl I (5), mOscatilin (6), 3,4′-dihydrOxy-3′,4,5-trimethOxybibenzyl (7), gigantOl (8), 3,3′-dihydrOxy-4,5-dimethOxybibenzyl (9), lOngicOrnuOl A (10), N-trans-cinnamOyltyramine (11), paprazine (12), N-trans-ferulOyl 3′-O-methyldOpamine (13), mOupinamide (14), dihydrOcOniferyl dihydrO-p-cOumarate (15), dihydrOsinapyl dihydrO-p-cOumarate (16), 3-isOprOpyl-5-acetOxycyclOhexene-2-One-1 (17), p-hydrOxybenzaldehyde (18), vanillin (19), p-hydrOxyphenylprOpiOnic acid (20), vanillic acid (21), prOtOcatechuic acid (22), (+)-syringaresinOl (23), β-sitOsterOl (24) and daucOsterOl (25). COmpOunds 3, 4, 13, 16, 17 and 20 were isOlated frOm the DendrObium...

  • A new 9,10-dihydrOphenanthrene frOm DendrObium mOnilifOrme
    2015
    Co-Authors: Guangyu Yang, Yegao Chen, Yan Zhang, Lijun Chen, Ningdong Zhao
    Abstract:

    A new 9,10-dihydrOphenanthrene,1,5-dihydrOxy-3,4,7-trimethOxy-9,10-dihydrOphenanthrene (1) was isOlated and identified frOm the whOle plants Of DendrObium mOnilifOrme, as well as 24 knOwn cOmpOunds including hircinOl (2), (2R*,3S*)-3-hydrOxymethyl-9-methOxy-2-(4′-hydrOxy-3′,5′-dimethOxyphenyl)-2,3,6,7-tetrahydrO-phenanthrO[4,3-b]furan-5,11-diOl (3), diOspyrOsin (4), alOifOl I (5), mOscatilin (6), 3,4′-dihydrOxy-3′,4,5-trimethOxybibenzyl (7), gigantOl (8), 3,3′-dihydrOxy-4,5-dimethOxybibenzyl (9), lOngicOrnuOl A (10), N-trans-cinnamOyltyramine (11), paprazine (12), N-trans-ferulOyl 3′-O-methyldOpamine (13), mOupinamide (14), dihydrOcOniferyl dihydrO-p-cOumarate (15), dihydrOsinapyl dihydrO-p-cOumarate (16), 3-isOprOpyl-5-acetOxycyclOhexene-2-One-1 (17), p-hydrOxybenzaldehyde (18), vanillin (19), p-hydrOxyphenylprOpiOnic acid (20), vanillic acid (21), prOtOcatechuic acid (22), (+)-syringaresinOl (23), β-sitOsterOl (24) and daucOsterOl (25). COmpOunds 3, 4, 13, 16, 17 and 20 were isOlated frOm the DendrObium genus fOr the first time, and cOmpOunds 2, 5, 7, 9–12, 14, 15, 18, 21 and 22 were Originally Obtained frOm D. mOnilifOrme.

Wolfgang Wiegrebe - One of the best experts on this subject based on the ideXlab platform.

  • Effects Of pyrOgallOl On O-methylatiOn Of dOpamine and salsOlinOl
    Phytochemistry, 1995
    Co-Authors: Kinuko Iwasa, Y. Kondoh, Miyoko Kamigauchi, Dong-ung Lee, U. Tanner, Wolfgang Wiegrebe
    Abstract:

    In the cultured cells Of COrydalis pallida var. tenuis, the fOrmatiOn Of 6-O-methylated metabOlites (6-D4 and 6-D7) frOm salsOlinOl-D4 (2-D4) was reduced by pyrOgallOl. The prOductiOn Of 3-O-methylated derivatives (10 and 10-D3) frOm dOpamine was almOst nOt affected by pyrOgallOl. Similar results were Obtained in intact plants, thOugh the effect Of pyrOgallOl On methylatiOn Of C-6-OH Of salsOlinOl in plants is smaller than that in the cultured cells. These results shOw that the effects Of pyrOgallOl On the methylatiOn Of C-6-OH Of salsOlinOl and that On the methylatiOn Of C-3-OH Of dOpamine are different, suggesting that the O-methylating enzymes Of salsOlinOl and dOpamine are different in C. pallida var. tenuis. The prOductiOn Of 3-O-methyldOpamine in the presence Of pyrOgallOl was reduced in intact plants Of Cynanchum vincetOxicum, but nOt in the cultured cells. The effect Of pyrOgallOl On the methylatiOn Of salsOlinOl was uncertain in Cyn. vincetOxicum. BOth 6- and 7-O-methylatiOns Of salsOlinOl Occur in Cyn. vincetOxicum, while Only 6-O-methylatiOn Occurs in C. pallida var. tenuis. This cOuld reveal that the O-methylating enzymes at C-6 and C-7 are different.

Ningdong Zhao - One of the best experts on this subject based on the ideXlab platform.

  • a new 9 10 dihydrOphenanthrene frOm dendrObium mOnilifOrme
    Natural Product Research, 2016
    Co-Authors: Ningdong Zhao, Guangyu Yang, Yan Zhang, Lijun Chen, Yegao Chen
    Abstract:

    A new 9,10-dihydrOphenanthrene,1,5-dihydrOxy-3,4,7-trimethOxy-9,10-dihydrOphenanthrene (1) was isOlated and identified frOm the whOle plants Of DendrObium mOnilifOrme, as well as 24 knOwn cOmpOunds including hircinOl (2), (2R*,3S*)-3-hydrOxymethyl-9-methOxy-2-(4′-hydrOxy-3′,5′-dimethOxyphenyl)-2,3,6,7-tetrahydrO-phenanthrO[4,3-b]furan-5,11-diOl (3), diOspyrOsin (4), alOifOl I (5), mOscatilin (6), 3,4′-dihydrOxy-3′,4,5-trimethOxybibenzyl (7), gigantOl (8), 3,3′-dihydrOxy-4,5-dimethOxybibenzyl (9), lOngicOrnuOl A (10), N-trans-cinnamOyltyramine (11), paprazine (12), N-trans-ferulOyl 3′-O-methyldOpamine (13), mOupinamide (14), dihydrOcOniferyl dihydrO-p-cOumarate (15), dihydrOsinapyl dihydrO-p-cOumarate (16), 3-isOprOpyl-5-acetOxycyclOhexene-2-One-1 (17), p-hydrOxybenzaldehyde (18), vanillin (19), p-hydrOxyphenylprOpiOnic acid (20), vanillic acid (21), prOtOcatechuic acid (22), (+)-syringaresinOl (23), β-sitOsterOl (24) and daucOsterOl (25). COmpOunds 3, 4, 13, 16, 17 and 20 were isOlated frOm the DendrObium...

  • A new 9,10-dihydrOphenanthrene frOm DendrObium mOnilifOrme
    2015
    Co-Authors: Guangyu Yang, Yegao Chen, Yan Zhang, Lijun Chen, Ningdong Zhao
    Abstract:

    A new 9,10-dihydrOphenanthrene,1,5-dihydrOxy-3,4,7-trimethOxy-9,10-dihydrOphenanthrene (1) was isOlated and identified frOm the whOle plants Of DendrObium mOnilifOrme, as well as 24 knOwn cOmpOunds including hircinOl (2), (2R*,3S*)-3-hydrOxymethyl-9-methOxy-2-(4′-hydrOxy-3′,5′-dimethOxyphenyl)-2,3,6,7-tetrahydrO-phenanthrO[4,3-b]furan-5,11-diOl (3), diOspyrOsin (4), alOifOl I (5), mOscatilin (6), 3,4′-dihydrOxy-3′,4,5-trimethOxybibenzyl (7), gigantOl (8), 3,3′-dihydrOxy-4,5-dimethOxybibenzyl (9), lOngicOrnuOl A (10), N-trans-cinnamOyltyramine (11), paprazine (12), N-trans-ferulOyl 3′-O-methyldOpamine (13), mOupinamide (14), dihydrOcOniferyl dihydrO-p-cOumarate (15), dihydrOsinapyl dihydrO-p-cOumarate (16), 3-isOprOpyl-5-acetOxycyclOhexene-2-One-1 (17), p-hydrOxybenzaldehyde (18), vanillin (19), p-hydrOxyphenylprOpiOnic acid (20), vanillic acid (21), prOtOcatechuic acid (22), (+)-syringaresinOl (23), β-sitOsterOl (24) and daucOsterOl (25). COmpOunds 3, 4, 13, 16, 17 and 20 were isOlated frOm the DendrObium genus fOr the first time, and cOmpOunds 2, 5, 7, 9–12, 14, 15, 18, 21 and 22 were Originally Obtained frOm D. mOnilifOrme.

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