The Experts below are selected from a list of 5814 Experts worldwide ranked by ideXlab platform
Mohammad Tabarestani - One of the best experts on this subject based on the ideXlab platform.
-
the predictive role of amylase and lipase levels on pancreas injury diagnosis in patients with Blunt Abdominal Trauma
Hormone Molecular Biology and Clinical Investigation, 2020Co-Authors: Seyed Mohammad Hosseininejad, Farzad Bozorgi, Touraj Assadi, Seyyed Hosein Montazar, Fatemeh Jahanian, Vahid Hoseini, Mahboobeh Shamsaee, Mohammad TabarestaniAbstract:Objectives Despite the low incidence of pancreatic injury in the Abdominal Blunt Trauma (BTA), its early diagnosis is very important; since pancreatic injury is associated with high rates of morbidity and mortality. However, due to the high association of pancreatic injury with injury of other Abdominal organs, its diagnosis may be delayed and complicated. The use of imaging modalities is also subject to limitations for reasons such as cost, unavailability, and harmfulness. Consequently, the present study aimed to investigate the predictive role of amylase and lipase enzyme levels in the final diagnosis of pancreatic injury in patients with BTA. Methods In a prospective diagnostic study, 384 patients with BTA referring to Imam Khomeini hospital of Sari (north of Iran) were enrolled according to the inclusion and exclusion criteria. Initial patient data including age and sex were recorded. Blood samples were analyzed in the laboratory to measure complete blood count (CBC), amylase and lipase enzyme levels. Patients were followed up during hospitalization and focal ultrasound for Abdominal Trauma (FAST), CT-Scan and laparotomy results were recorded. Finally, the data was analyzed using SPSS version 22. Results The level of amylase enzyme was significantly higher in males (p = 0.04), but the level of lipase enzyme was not significantly different between two genders (p > 0.05). The most common symptoms and signs in patients were pain, tenderness, and hematoma, respectively. The frequency of pancreatic injury in all patients with Blunt Abdominal Trauma was 7.5% based of FAST, 7% based on CT-Scan and 12.4% based on laparotomy. Comparison of laboratory findings based on FAST, CT-Scan and laparotomy results showed that the level of amylase and lipase enzymes in patients with internal organ and pancreatic damage were higher than in patients without internal organ injury (p 0.05). However, comparison of laboratory findings based on CT-Scan and laparotomy results showed a significant increase in the level of amylase and lipase enzymes in patients with pancreatic Trauma compared to patients with injury of other organs (p < 0.001). Conclusions The results of this study showed that pancreatic injury in Blunt Trauma is associated with a significant increase in levels of amylase and lipase enzymes. In addition, an increase in levels of amylase and lipase enzymes is associated with internal organ damage. Serum amylase and lipase levels can be used as useful biomarkers to decide whether to perform CT-Scan or laparotomy.
Cirillo B - One of the best experts on this subject based on the ideXlab platform.
-
Hollow viscus injuries: predictors of outcome and role of diagnostic delay
Dove Medical Press, 2017Co-Authors: Mingoli A, La Torre M, Brachini G, Costa G, Balducci G, Frezza B, Sgarzini G, Cirillo BAbstract:Andrea Mingoli,1,2 Marco La Torre,1,2 Gioia Brachini,1,2 Gianluca Costa,3 Genoveffa Balducci,3 Barbara Frezza,3 Giovanna Sgarzini,4 Bruno Cirillo1,2 1Emergency Department, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy; 2Department of Surgery P Valdoni, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy; 3Surgical Department of Clinical Sciences, Biomedical Technologies and Translational Medicine, Sant’Andrea Hospital, Sapienza University of Rome, Rome, Italy; 4Department of Surgery, S Giovanni Addolorata Hospital, Rome, Italy Introduction: Hollow viscus injuries (HVIs) are uncommon but potentially catastrophic conditions with high mortality and morbidity rates. The aim of this study was to analyze our 16-year experience with patients undergoing surgery for Blunt or penetrating bowel Trauma to identify prognostic factors with particular attention to the influence of diagnostic delay on outcome. Methods: From our multicenter Trauma registry, we selected 169 consecutive patients with an HVI, enrolled from 2000 to 2016. Preoperative, intraoperative, and postoperative data were analyzed to assess determinants of mortality, morbidity, and length of stay by univariate and multivariate analysis models. Results: Overall mortality and morbidity rates were 15.9% and 36.1%, respectively. The mean length of hospital stay was 23±7 days. Morbidity was independently related to an increase of white blood cells (P=0.01), and to delay of treatment >6 hours (P=0.033), while Injury Severity Score (ISS) (P=0.01), presence of shock (P=0.01), and a low diastolic arterial pressure registered at emergency room admission (P=0.02) significantly affected postoperative mortality. Conclusion: There is evidence that patients with clinical signs of shock, low diastolic pressure at admission, and high ISS are at increased risk of postoperative mortality. Leukocytosis and delayed treatment (>6 hours) were independent predictors of postoperative morbidity. More effort should be made to increase the preoperative detection rate of HVI and reduce the delay of treatment. Keywords: bowel injuries, hollow viscus injuries, Abdominal Blunt Trauma, Trauma, Traumatic bowel perforation, BIP
Tamara Solange Rosu - One of the best experts on this subject based on the ideXlab platform.
-
Abdominal HOLLOW VISCUS Trauma IN CHILDREN, INJURY MECHANISMS AND TREATMENT PRINCIPLES
'AMALTEA Medical Publishing House', 2019Co-Authors: Elena Tarca, Irina Ciomaga, Nicolae Nistor, Irina Criscov, Tamara Solange RosuAbstract:Abdominal hollow viscus Trauma represents an important cause of pediatric morbidity, following head, vertebral column, spinal cord and thoracic injuries, whose main mechanisms of production are road traffic accidents, falls with Abdominal impact, sports injuries, physical aggression and explosions. If there is a penetrating Abdominal Trauma, most frequently it associates hollow organ injuries, while Abdominal Blunt Trauma is associated more often with parenchymal injuries, with effects on the hemodynamic status. Imaging and paraclinical investigations used to evaluate an Abdominal Trauma consist of thoraco-Abdominal radiography in orthostatic position, Abdominal ultrasonography, diagnostic peritoneal lavage, Abdominal computed tomography and exploratory laparoscopy. Unlike penetrating injuries, when surgical exploration is obvious, in the case of young children with Abdominal contusions, the injuries involving hollow viscus can be overlooked at time of the initial assessment, because of a poor communication between doctor and patient, difficult interpretation of symptoms when there are other injuries associated, but also because of the intial lack of ultrasound signs of perforation. Delayed diagnosis and adequate treatment lead to extended duration of hospitalisation, to elevated costs and rates of morbidity. The incidence of mortality caused by Abdominal Trauma associated with hollow viscus penetration is approximately 10%, being more elevated as the digestive injuries are multiple or associated with other lesions
Juwita Nova - One of the best experts on this subject based on the ideXlab platform.
-
Diagnostic validity of Blunt Abdominal Trauma scoring system (BATSS) on Blunt adominal Trauma in Sanglah General Hospital, Denpasar, Bali
'DiscoverSys Inc.', 2019Co-Authors: Karjosukarso, Adityas Sukmadi, Wiargitha I Ketut, Mahadewa, Tjokorda Gde Bagus, Juwita NovaAbstract:Background: Abdominal Trauma is the third leading cause of death in Trauma patients and can be found in about 7-10% of the total number of Trauma cases. The Blunt Abdominal Trauma Scoring System (BATSS) provides a high-accuracy score system for diagnosing injury to intra-Abdominal organs in Blunt Abdominal Trauma patients based on clinical features, such as patient history, physical examination, and Focused Assesment with Sonography for Trauma (FAST). This study aimed to determine the validity of the diagnostic value of BATSS score in cases of Blunt Abdominal Trauma.Method: This research was conducted at Sanglah General Hospital, Denpasar with a total sample of 44 patients. The subjects were Abdominal Blunt Trauma patients who meet the inclusion and exclusion criteria. This study was a retrospective study to determined the validity of the BATSS score.Result: Of the 44 patients, BATSS score ³12 was found at 34 (77.3%) and BATTS <12 scores of 10 (22.7%). For groups with BATSS score ³12, there were 32 (94.11%) patients. As for the group with BATSS score <12, there were 3 (30%) patients with organ rupture. A validity test of BATSS score obtained showed 91.4% sensitivity, 77.77% specificity, positive predictive value 94.1%, negative predictive value 70%.Conclusion: BATSS can be a tool of early identification and stratification of patients at high risk of the occurrence of intra-Abdominal organ injury due to Blunt Abdominal Trauma
Seyed Mohammad Hosseininejad - One of the best experts on this subject based on the ideXlab platform.
-
the predictive role of amylase and lipase levels on pancreas injury diagnosis in patients with Blunt Abdominal Trauma
Hormone Molecular Biology and Clinical Investigation, 2020Co-Authors: Seyed Mohammad Hosseininejad, Farzad Bozorgi, Touraj Assadi, Seyyed Hosein Montazar, Fatemeh Jahanian, Vahid Hoseini, Mahboobeh Shamsaee, Mohammad TabarestaniAbstract:Objectives Despite the low incidence of pancreatic injury in the Abdominal Blunt Trauma (BTA), its early diagnosis is very important; since pancreatic injury is associated with high rates of morbidity and mortality. However, due to the high association of pancreatic injury with injury of other Abdominal organs, its diagnosis may be delayed and complicated. The use of imaging modalities is also subject to limitations for reasons such as cost, unavailability, and harmfulness. Consequently, the present study aimed to investigate the predictive role of amylase and lipase enzyme levels in the final diagnosis of pancreatic injury in patients with BTA. Methods In a prospective diagnostic study, 384 patients with BTA referring to Imam Khomeini hospital of Sari (north of Iran) were enrolled according to the inclusion and exclusion criteria. Initial patient data including age and sex were recorded. Blood samples were analyzed in the laboratory to measure complete blood count (CBC), amylase and lipase enzyme levels. Patients were followed up during hospitalization and focal ultrasound for Abdominal Trauma (FAST), CT-Scan and laparotomy results were recorded. Finally, the data was analyzed using SPSS version 22. Results The level of amylase enzyme was significantly higher in males (p = 0.04), but the level of lipase enzyme was not significantly different between two genders (p > 0.05). The most common symptoms and signs in patients were pain, tenderness, and hematoma, respectively. The frequency of pancreatic injury in all patients with Blunt Abdominal Trauma was 7.5% based of FAST, 7% based on CT-Scan and 12.4% based on laparotomy. Comparison of laboratory findings based on FAST, CT-Scan and laparotomy results showed that the level of amylase and lipase enzymes in patients with internal organ and pancreatic damage were higher than in patients without internal organ injury (p 0.05). However, comparison of laboratory findings based on CT-Scan and laparotomy results showed a significant increase in the level of amylase and lipase enzymes in patients with pancreatic Trauma compared to patients with injury of other organs (p < 0.001). Conclusions The results of this study showed that pancreatic injury in Blunt Trauma is associated with a significant increase in levels of amylase and lipase enzymes. In addition, an increase in levels of amylase and lipase enzymes is associated with internal organ damage. Serum amylase and lipase levels can be used as useful biomarkers to decide whether to perform CT-Scan or laparotomy.
