The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Glenn C Cockerham - One of the best experts on this subject based on the ideXlab platform.
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Abiotrophia defectiva causing infectious crystalline keratopathy and corneal ulcer after penetrating keratoplasty a case report
Journal of Ophthalmic Inflammation and Infection, 2013Co-Authors: Yannis M Paulus, Glenn C CockerhamAbstract:Infectious crystalline keratopathy is commonly caused by Streptococcus viridans and other gram positive organisms. We present the first case of infectious crystalline keratopathy that developed into a corneal ulcer and grew Abiotrophia defectiva which responded well to topical and systemic antimicrobial therapy and did not require re-grafting. A 78-year-old man underwent penetrating keratoplasty for pseudophakic bullous keratopathy. He presented 1.5 years later with infectious crystalline keratopathy which progressed to a corneal ulcer. The patient received topical fortified vancomycin and moxifloxacin, as well as oral moxifloxacin. The corneal ulcer base was cultured and grew A. defectiva, or nutritionally deficient streptococcus. Complete resolution of the corneal infiltrates was obtained within three months. Nutritionally deficient streptococcus has been implicated in numerous human diseases, including endocarditis, and is increasingly being recognized as an important pathogen. This represents the second reported case of A. defectiva causing infectious crystalline keratopathy in humans and the first case of A. defectiva successfully treated with antibiotics. This case shows that aggressive antibiotic therapy can be effective in A. defectiva-associated infectious crystalline keratopathy.
M. Russlies - One of the best experts on this subject based on the ideXlab platform.
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CASE REPORT Total knee arthroplasty infection due to Abiotrophia defectiva
2015Co-Authors: A. Ince, B. Tiemer, J. Gille, C. Boos, M. RussliesAbstract:The first documented case of knee alloarthroplasty infection due to Abiotrophia defectiva, formerly known as nutritionally variant streptococci (NVS) and Streptococcus defectivus, is presented. The microbiology of this bacterium is discussed and clinical features of previously reported cases of infections by NVS are reviewed briefly
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Total knee arthroplasty infection due to Abiotrophia defectiva.
Journal of medical microbiology, 2002Co-Authors: A. Ince, B. Tiemer, J. Gille, C. Boos, M. RussliesAbstract:The first documented case of knee alloarthroplasty infection due to Abiotrophia defectiva, formerly known as nutritionally variant streptococci (NVS) and Streptococcus defectivus, is presented. The microbiology of this bacterium is discussed and clinical features of previously reported cases of infections by NVS are reviewed briefly.
Wim Ang - One of the best experts on this subject based on the ideXlab platform.
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Abiotrophia defectiva infection of a total hip arthroplasty diagnosed by 16S rRNA gene sequencing
Diagnostic microbiology and infectious disease, 2011Co-Authors: Wouter Rozemeijer, Timothy U. Jiya, Martine C. Rijnsburger, Edou R. Heddema, Paul H. M. Savelkoul, Wim AngAbstract:We describe a case of a total hip arthroplasty infection caused by Abiotrophia defectiva, identified by 16S rRNA gene sequencing. Removal of the prosthesis followed by antibiotic treatment resulted in a good clinical outcome. 16S rRNA gene sequencing can be a useful tool in diagnosing infection with this fastidious microorganism that can easily be misidentified using phenotypic identification methods.
Kwokyung Yuen - One of the best experts on this subject based on the ideXlab platform.
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granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16s rrna gene sequencing
Journal of Medical Microbiology, 2003Co-Authors: Patrick C Y Woo, Ami Meiyuk Fung, Susanna K P Lau, Benedict Yinleung Chan, Siukau Chiu, Jade Leelee Teng, T L Que, Raymond W H Yung, Kwokyung YuenAbstract:Traditionally, the identification, epidemiology and spectrum of clinical diseases caused by Granulicatella adiacens and Abiotrophia defectiva are dependent upon their phenotypic characterization. During a 6-year period (July 1995-June 2001), seven and two alpha-haemolytic streptococci were identified as G. adiacens and A. defectiva, respectively, by 16S rRNA gene sequencing. Three patients with haematological malignancies and neutropenic fever had primary bacteraemia. Three patients with valvular problems or congenital heart disease had infective endocarditis. A patient with ischemic heart disease and cerebrovascular accident had infected aortic atheroma with dissection. A patient with recurrent pyogenic cholangitis had acute cholangitis and a patient with polypoid cystitis and benign prostatic hypertrophy had acute prostatitis. Four of the nine patients died, including all three with G. adiacens infective endocarditis or infected atheroma. For the seven G. adiacens isolates, the API 20 STREP system successfully identified one and five isolates as G. adiacens with >95 % and 80-90 % confidence, respectively, whereas the Vitek System (GPI) and ATB Expression system (ID32 STREP) successfully identified none and one isolate as G. adiacens. Of the two A. defectiva isolates, none of the three systems successfully identified either of them as A. defectiva. 16S rRNA gene sequencing is the technique of choice for identifying G. adiacens and A. defectiva, and early surgical intervention should be considered when G. adiacens endocarditis is diagnosed.
A. Ince - One of the best experts on this subject based on the ideXlab platform.
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CASE REPORT Total knee arthroplasty infection due to Abiotrophia defectiva
2015Co-Authors: A. Ince, B. Tiemer, J. Gille, C. Boos, M. RussliesAbstract:The first documented case of knee alloarthroplasty infection due to Abiotrophia defectiva, formerly known as nutritionally variant streptococci (NVS) and Streptococcus defectivus, is presented. The microbiology of this bacterium is discussed and clinical features of previously reported cases of infections by NVS are reviewed briefly
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Total knee arthroplasty infection due to Abiotrophia defectiva.
Journal of medical microbiology, 2002Co-Authors: A. Ince, B. Tiemer, J. Gille, C. Boos, M. RussliesAbstract:The first documented case of knee alloarthroplasty infection due to Abiotrophia defectiva, formerly known as nutritionally variant streptococci (NVS) and Streptococcus defectivus, is presented. The microbiology of this bacterium is discussed and clinical features of previously reported cases of infections by NVS are reviewed briefly.
