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Lacaz, Carlos Da Silva - One of the best experts on this subject based on the ideXlab platform.

  • Aspergilosis cerebral causada por Aspergillus fumigatus en paciente con SIDA: primer reporte de caso demostrado por cultivo en Brasil
    Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo, 2005
    Co-Authors: Vidal, José E., Augusto Penalva C. De Oliveira, Dauar, Rafi F., Melhem, Marcia S.c., Szeszs Walderez, Pukinskas, Sandra R.b.s., Coelho, João F.g.s., Lins, Diogo L.m., Costa, Silvia F., Lacaz, Carlos Da Silva
    Abstract:

    Cerebral aspergillosis is a rare cause of brain expansive lesion in AIDS patients. We report the first culture-proven case of brain Abscess due to Aspergillus fumigatus in a Brazilian AIDS patient. The patient, a 26 year-old male with human immunodeficiency virus (HIV) infection and history of pulmonary tuberculosis and cerebral toxoplasmosis, had fever, cough, dyspnea, and two episodes of seizures. The brain computerized tomography (CT) showed a bi-parietal and parasagittal hypodense lesion with peripheral enhancement, and significant mass effect. There was started anti-Toxoplasma treatment. Three weeks later, the patient presented mental confusion, and a new brain CT evidenced increase in the lesion. He underwent brain biopsy, draining 10 mL of purulent material. The direct mycological examination revealed septated and hyaline hyphae. There was started amphotericin B deoxycholate. The culture of the material demonstrated presence of the Aspergillus fumigatus. The following two months, the patient was submitted to three surgeries, with insertion of drainage catheter and administration of amphotericin B intralesional. Three months after hospital admission, his neurological condition suffered discrete changes. However, he died due to intrahospital pneumonia. Brain Abscess caused by Aspergillus fumigatus must be considered in the differential diagnosis of the brain expansive lesions in AIDS patients in Brazil.La aspergilosis cerebral es una causa rara de lesión expansiva cerebral en pacientes con SIDA. Presentamos el primer reporte de un absceso cerebral causado por Aspergillus fumigatus en un paciente brasileño con SIDA. El paciente, de 26 años de edad, presentaba antecedentes de infección por el virus de la inmunodeficiencia humana (VIH), tuberculosis pulmonar y toxoplasmosis cerebral. Manifestó fiebre, tos, disnea y dos episódios de convulsiones. La tomografía computadorizada (TC) demostró una lesión hipodensa parasagital y bi-parietal con realce periférico e importante efecto de masa. Se inició tratamiento anti-Toxoplasma. Tres semanas después, el paciente evidenció confusión mental y una nueva TC de cráneo mostró aumento de la lesión. Se realizó biopsia cerebral con drenaje de 10 mL de material purulento. El examen micológico directo reveló hifas hialinas septadas. Se inició anfotericina B deoxicolato. La cultura del material demostró presencia de Aspergillus fumigatus. En los siguientes dos meses el paciente fue sometido a otras tres cirugías, insertándose un catéter de drenaje y administrándose anfotericina B intralesional. Tres meses después de la admisión hospitalaria, la condición neurológica del paciente sufrió discretos cambios. Sin embargo, falleció debido a neumonia intrahospitalaria. Aunque muy raros, los abscesos cerebrales causados por Aspergillus fumigatus deben ser considerados en el diagnóstico diferencial de las lesiones expansivas cerebrales en pacientes con SIDA

Carlos Da Silva Lacaz - One of the best experts on this subject based on the ideXlab platform.

  • Cerebral aspergillosis due to Aspergillus fumigatus in AIDS patient: first culture - proven case reported in Brazil Aspergilosis cerebral causada por Aspergillus fumigatus en paciente con SIDA: primer reporte de caso demostrado por cultivo en Brasil
    Universidade de São Paulo, 2005
    Co-Authors: José E. Vidal, Rafi F. Dauar, Marcia S.c. Melhem, Walderez Szeszs, Sandra R.b.s. Pukinskas, João F.g.s. Coelho, Diogo L.m. Lins, Silvia F. Costa, Augusto Penalva C. De Oliveira, Carlos Da Silva Lacaz
    Abstract:

    Cerebral aspergillosis is a rare cause of brain expansive lesion in AIDS patients. We report the first culture-proven case of brain Abscess due to Aspergillus fumigatus in a Brazilian AIDS patient. The patient, a 26 year-old male with human immunodeficiency virus (HIV) infection and history of pulmonary tuberculosis and cerebral toxoplasmosis, had fever, cough, dyspnea, and two episodes of seizures. The brain computerized tomography (CT) showed a bi-parietal and parasagittal hypodense lesion with peripheral enhancement, and significant mass effect. There was started anti-Toxoplasma treatment. Three weeks later, the patient presented mental confusion, and a new brain CT evidenced increase in the lesion. He underwent brain biopsy, draining 10 mL of purulent material. The direct mycological examination revealed septated and hyaline hyphae. There was started amphotericin B deoxycholate. The culture of the material demonstrated presence of the Aspergillus fumigatus. The following two months, the patient was submitted to three surgeries, with insertion of drainage catheter and administration of amphotericin B intralesional. Three months after hospital admission, his neurological condition suffered discrete changes. However, he died due to intrahospital pneumonia. Brain Abscess caused by Aspergillus fumigatus must be considered in the differential diagnosis of the brain expansive lesions in AIDS patients in Brazil.La aspergilosis cerebral es una causa rara de lesión expansiva cerebral en pacientes con SIDA. Presentamos el primer reporte de un absceso cerebral causado por Aspergillus fumigatus en un paciente brasileño con SIDA. El paciente, de 26 años de edad, presentaba antecedentes de infección por el virus de la inmunodeficiencia humana (VIH), tuberculosis pulmonar y toxoplasmosis cerebral. Manifestó fiebre, tos, disnea y dos episódios de convulsiones. La tomografía computadorizada (TC) demostró una lesión hipodensa parasagital y bi-parietal con realce periférico e importante efecto de masa. Se inició tratamiento anti-Toxoplasma. Tres semanas después, el paciente evidenció confusión mental y una nueva TC de cráneo mostró aumento de la lesión. Se realizó biopsia cerebral con drenaje de 10 mL de material purulento. El examen micológico directo reveló hifas hialinas septadas. Se inició anfotericina B deoxicolato. La cultura del material demostró presencia de Aspergillus fumigatus. En los siguientes dos meses el paciente fue sometido a otras tres cirugías, insertándose un catéter de drenaje y administrándose anfotericina B intralesional. Tres meses después de la admisión hospitalaria, la condición neurológica del paciente sufrió discretos cambios. Sin embargo, falleció debido a neumonia intrahospitalaria. Aunque muy raros, los abscesos cerebrales causados por Aspergillus fumigatus deben ser considerados en el diagnóstico diferencial de las lesiones expansivas cerebrales en pacientes con SIDA

Augusto Penalva C. De Oliveira - One of the best experts on this subject based on the ideXlab platform.

  • Cerebral aspergillosis due to Aspergillus fumigatus in AIDS patient: first culture - proven case reported in Brazil Aspergilosis cerebral causada por Aspergillus fumigatus en paciente con SIDA: primer reporte de caso demostrado por cultivo en Brasil
    Universidade de São Paulo, 2005
    Co-Authors: José E. Vidal, Rafi F. Dauar, Marcia S.c. Melhem, Walderez Szeszs, Sandra R.b.s. Pukinskas, João F.g.s. Coelho, Diogo L.m. Lins, Silvia F. Costa, Augusto Penalva C. De Oliveira, Carlos Da Silva Lacaz
    Abstract:

    Cerebral aspergillosis is a rare cause of brain expansive lesion in AIDS patients. We report the first culture-proven case of brain Abscess due to Aspergillus fumigatus in a Brazilian AIDS patient. The patient, a 26 year-old male with human immunodeficiency virus (HIV) infection and history of pulmonary tuberculosis and cerebral toxoplasmosis, had fever, cough, dyspnea, and two episodes of seizures. The brain computerized tomography (CT) showed a bi-parietal and parasagittal hypodense lesion with peripheral enhancement, and significant mass effect. There was started anti-Toxoplasma treatment. Three weeks later, the patient presented mental confusion, and a new brain CT evidenced increase in the lesion. He underwent brain biopsy, draining 10 mL of purulent material. The direct mycological examination revealed septated and hyaline hyphae. There was started amphotericin B deoxycholate. The culture of the material demonstrated presence of the Aspergillus fumigatus. The following two months, the patient was submitted to three surgeries, with insertion of drainage catheter and administration of amphotericin B intralesional. Three months after hospital admission, his neurological condition suffered discrete changes. However, he died due to intrahospital pneumonia. Brain Abscess caused by Aspergillus fumigatus must be considered in the differential diagnosis of the brain expansive lesions in AIDS patients in Brazil.La aspergilosis cerebral es una causa rara de lesión expansiva cerebral en pacientes con SIDA. Presentamos el primer reporte de un absceso cerebral causado por Aspergillus fumigatus en un paciente brasileño con SIDA. El paciente, de 26 años de edad, presentaba antecedentes de infección por el virus de la inmunodeficiencia humana (VIH), tuberculosis pulmonar y toxoplasmosis cerebral. Manifestó fiebre, tos, disnea y dos episódios de convulsiones. La tomografía computadorizada (TC) demostró una lesión hipodensa parasagital y bi-parietal con realce periférico e importante efecto de masa. Se inició tratamiento anti-Toxoplasma. Tres semanas después, el paciente evidenció confusión mental y una nueva TC de cráneo mostró aumento de la lesión. Se realizó biopsia cerebral con drenaje de 10 mL de material purulento. El examen micológico directo reveló hifas hialinas septadas. Se inició anfotericina B deoxicolato. La cultura del material demostró presencia de Aspergillus fumigatus. En los siguientes dos meses el paciente fue sometido a otras tres cirugías, insertándose un catéter de drenaje y administrándose anfotericina B intralesional. Tres meses después de la admisión hospitalaria, la condición neurológica del paciente sufrió discretos cambios. Sin embargo, falleció debido a neumonia intrahospitalaria. Aunque muy raros, los abscesos cerebrales causados por Aspergillus fumigatus deben ser considerados en el diagnóstico diferencial de las lesiones expansivas cerebrales en pacientes con SIDA

  • Aspergilosis cerebral causada por Aspergillus fumigatus en paciente con SIDA: primer reporte de caso demostrado por cultivo en Brasil
    Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo, 2005
    Co-Authors: Vidal, José E., Augusto Penalva C. De Oliveira, Dauar, Rafi F., Melhem, Marcia S.c., Szeszs Walderez, Pukinskas, Sandra R.b.s., Coelho, João F.g.s., Lins, Diogo L.m., Costa, Silvia F., Lacaz, Carlos Da Silva
    Abstract:

    Cerebral aspergillosis is a rare cause of brain expansive lesion in AIDS patients. We report the first culture-proven case of brain Abscess due to Aspergillus fumigatus in a Brazilian AIDS patient. The patient, a 26 year-old male with human immunodeficiency virus (HIV) infection and history of pulmonary tuberculosis and cerebral toxoplasmosis, had fever, cough, dyspnea, and two episodes of seizures. The brain computerized tomography (CT) showed a bi-parietal and parasagittal hypodense lesion with peripheral enhancement, and significant mass effect. There was started anti-Toxoplasma treatment. Three weeks later, the patient presented mental confusion, and a new brain CT evidenced increase in the lesion. He underwent brain biopsy, draining 10 mL of purulent material. The direct mycological examination revealed septated and hyaline hyphae. There was started amphotericin B deoxycholate. The culture of the material demonstrated presence of the Aspergillus fumigatus. The following two months, the patient was submitted to three surgeries, with insertion of drainage catheter and administration of amphotericin B intralesional. Three months after hospital admission, his neurological condition suffered discrete changes. However, he died due to intrahospital pneumonia. Brain Abscess caused by Aspergillus fumigatus must be considered in the differential diagnosis of the brain expansive lesions in AIDS patients in Brazil.La aspergilosis cerebral es una causa rara de lesión expansiva cerebral en pacientes con SIDA. Presentamos el primer reporte de un absceso cerebral causado por Aspergillus fumigatus en un paciente brasileño con SIDA. El paciente, de 26 años de edad, presentaba antecedentes de infección por el virus de la inmunodeficiencia humana (VIH), tuberculosis pulmonar y toxoplasmosis cerebral. Manifestó fiebre, tos, disnea y dos episódios de convulsiones. La tomografía computadorizada (TC) demostró una lesión hipodensa parasagital y bi-parietal con realce periférico e importante efecto de masa. Se inició tratamiento anti-Toxoplasma. Tres semanas después, el paciente evidenció confusión mental y una nueva TC de cráneo mostró aumento de la lesión. Se realizó biopsia cerebral con drenaje de 10 mL de material purulento. El examen micológico directo reveló hifas hialinas septadas. Se inició anfotericina B deoxicolato. La cultura del material demostró presencia de Aspergillus fumigatus. En los siguientes dos meses el paciente fue sometido a otras tres cirugías, insertándose un catéter de drenaje y administrándose anfotericina B intralesional. Tres meses después de la admisión hospitalaria, la condición neurológica del paciente sufrió discretos cambios. Sin embargo, falleció debido a neumonia intrahospitalaria. Aunque muy raros, los abscesos cerebrales causados por Aspergillus fumigatus deben ser considerados en el diagnóstico diferencial de las lesiones expansivas cerebrales en pacientes con SIDA

Toro, Ivan Felizardo Contrera - One of the best experts on this subject based on the ideXlab platform.

  • Negative-pressure pulmonary edema and hemorrhage associated with upper airway obstruction
    'FapUNIFESP (SciELO)', 2015
    Co-Authors: Mussi, Ricardo Kalaf, Toro, Ivan Felizardo Contrera
    Abstract:

    Negative-pressure pulmonary edema accompanied by hemorrhage as a manifestation of upper airway obstruction is an uncommon problem that is potentially life-threatening. The principal pathophysiological mechanism involved is the generation of markedly negative intrathoracic pressure, which leads to an increase in pulmonary vascular volume and pulmonary capillary transmural pressure, creating a risk of disruption of the alveolar-capillary membrane. We report the case of an adult male with diffuse alveolar hemorrhage following acute upper airway obstruction caused by the formation of a cervical and mediastinal Abscess resulting from the insertion of a metallic tracheal stent. The patient was treated through drainage of the Abscess, antibiotic therapy, and positive pressure mechanical ventilation. This article emphasizes the importance of including this entity in the differential diagnosis of acute lung injury after procedures involving upper airway instrumentation.O edema pulmonar por pressão negativa associado à hemorragia como manifestação de obstrução das vias aéreas superiores é um problema incomum com potencial risco de morte. O principal mecanismo fisiopatológico envolvido é a geração de uma acentuada pressão negativa intratorácica que eleva tanto o volume vascular como a pressão transmural capilar pulmonar, causando risco de ruptura da membrana alvéolo-capilar. Relatamos o caso de um paciente do sexo masculino com hemorragia alveolar difusa após obstrução aguda das vias aéreas superiores causada pela formação de um Abscesso cervical e mediastinal decorrente do implante de uma órtese traqueal metálica. O paciente foi tratado com drenagem do Abscesso, antibioticoterapia e ventilação mecânica com pressão positiva. Este artigo enfatiza a importância de incluir essa entidade no diagnóstico diferencial da lesão pulmonar aguda após procedimentos que envolvam a manipulação das vias aéreas superiores346420424Negative-pressure pulmonary edema accompanied by hemorrhage as a manifestation of upper airway obstruction is an uncommon problem that is potentially life-threatening. The principal pathophysiological mechanism involved is the generation of markedly negative intrathoracic pressure, which leads to an increase in pulmonary vascular volume and pulmonary capillary transmural pressure, creating a risk of disruption of the alveolar-capillary membrane. We report the case of an adult male with diffuse alveolar hemorrhage following acute upper airway obstruction caused by the formation of a cervical and mediastinal Abscess resulting from the insertion of a metallic tracheal stent. The patient was treated through drainage of the Abscess, antibiotic therapy, and positive pressure mechanical ventilation. This article emphasizes the importance of including this entity in the differential diagnosis of acute lung injury after procedures involving upper airway instrumentatio

  • Negative-pressure pulmonary edema and hemorrhage associated with upper airway obstruction
    Sociedade Brasileira de Pneumologia e Tisiologia, 2015
    Co-Authors: Mussi, Ricardo Kalaf, Toro, Ivan Felizardo Contrera
    Abstract:

    Negative-pressure pulmonary edema accompanied by hemorrhage as a manifestation of upper airway obstruction is an uncommon problem that is potentially life-threatening. The principal pathophysiological mechanism involved is the generation of markedly negative intrathoracic pressure, which leads to an increase in pulmonary vascular volume and pulmonary capillary transmural pressure, creating a risk of disruption of the alveolar-capillary membrane. We report the case of an adult male with diffuse alveolar hemorrhage following acute upper airway obstruction caused by the formation of a cervical and mediastinal Abscess resulting from the insertion of a metallic tracheal stent. The patient was treated through drainage of the Abscess, antibiotic therapy, and positive pressure mechanical ventilation. This article emphasizes the importance of including this entity in the differential diagnosis of acute lung injury after procedures involving upper airway instrumentation.O edema pulmonar por pressão negativa associado à hemorragia como manifestação de obstrução das vias aéreas superiores é um problema incomum com potencial risco de morte. O principal mecanismo fisiopatológico envolvido é a geração de uma acentuada pressão negativa intratorácica que eleva tanto o volume vascular como a pressão transmural capilar pulmonar, causando risco de ruptura da membrana alvéolo-capilar. Relatamos o caso de um paciente do sexo masculino com hemorragia alveolar difusa após obstrução aguda das vias aéreas superiores causada pela formação de um Abscesso cervical e mediastinal decorrente do implante de uma órtese traqueal metálica. O paciente foi tratado com drenagem do Abscesso, antibioticoterapia e ventilação mecânica com pressão positiva. Este artigo enfatiza a importância de incluir essa entidade no diagnóstico diferencial da lesão pulmonar aguda após procedimentos que envolvam a manipulação das vias aéreas superiores

Dave Wehdekinghernandez - One of the best experts on this subject based on the ideXlab platform.

  • osteomyelitis and periosteal reaction in a red brocket deer mazama americana
    Revista Colombiana De Ciencias Pecuarias, 2013
    Co-Authors: Ana M Henaoduque, Juliana Penastadlin, Dave Wehdekinghernandez
    Abstract:

    Summary Anamnesis and treatment approach: a female red brocket deer (Mazama americana , Erxleben 1777 ) presented a post-traumatic Abscess in the left-carpometacarpal joint. The deer was treated with enrofloxacin (5 mg/kg) and ivermectin (0.2 mg/kg) with no response. The animal underwent two surgical procedures to remove purulent material and perform adequate antisepsis as well as several antimicrobial therapies, with satisfactory results in a period of 68 days. Clinical and laboratory findings: according to the radiological and laboratory tests the animal developed a metacarpal bone osteomyelitis with periosteal reaction due to a beta-hemolytic Streptococcus Abscess. Conclusion: to our knowledge, this is the first report of medical procedures in this species. The most relevant findings and treatment schedule are discussed.  Key words: antimicrobial therapy, cervid, post-traumatic Abscess. Resumen Anamnesis y aproximacion terapeutica: una hembra de venado soche (Mazama americana), que presento un absceso postraumatico en la articulacion carpo-metacarpiana del miembro anterior izquierdo fue tratada con enrofloxacina (5 mg/kg) e ivermectina (0,2 mg/kg), sin responder al tratamiento. Se sometio a dos procedimientos quirurgicos con el fin de extraer el material purulento y realizar una antisepsia adecuada, ademas de varias terapias antibioticas, con resultados satisfactorios en un termino de 68 dias . Hallazgos clinicos y de laboratorio: de acuerdo a los resultados radiologicos y de laboratorio el animal desarrollo osteomielitis con reaccion periostica metacarpiana, debido a un absceso por Streptococcus beta-hemolitico. Conclusion: este es el primer reporte sobre procedimientos medicos en esta especie, se discuten los hallazgos clinicos y el esquema de tratamiento mas relevante.  Palabras clave: absceso postraumatico, cervido, terapia antimicrobiana. Resumo Historia e tratamento : uma femea de veado ( Mazama americana ) apresentou um Abscesso postraumatico na articulacao do carpo-metacarpo do membro esquerdo. Foi tratada com enrofloxacino (5 mg/kg) e ivermectina (0,2 mg/kg), sem responder ao tratamento. Logo foi submetida a dois procedimentos cirurgicos para remover o pus e fazer limpeza com antisseptico apropriado, alem de varias terapias antibioticas, com resultados satisfatorios em um periodo de 68 dias. Resultados clinicos e laboratoriais : de acordo com os resultados dos exames radiologicos e de laboratorio, o animal desenvolveu osteomielite no metacarpo com reacao periosteal devido a um Abscesso por Streptococcus beta-hemolitico. Conclusao: este e o primeiro relatorio sobre procedimentos medicos nesta especie, discutimos os achados clinicos e o sistema de tratamento adequado.  Palavras chave: Abscesso pos-traumatico, cervideo, terapia antimicrobiana.

  • osteomyelitis and periosteal reaction in a red brocket deer mazama americana
    Revista Colombiana De Ciencias Pecuarias, 2013
    Co-Authors: Ana M Henaoduque, Juliana Penastadlin, Dave Wehdekinghernandez
    Abstract:

    Summary Anamnesis and treatment approach: a female red brocket deer (Mazama americana , Erxleben 1777 ) presented a post-traumatic Abscess in the left-carpometacarpal joint. The deer was treated with enrofloxacin (5 mg/kg) and ivermectin (0.2 mg/kg) with no response. The animal underwent two surgical procedures to remove purulent material and perform adequate antisepsis as well as several antimicrobial therapies, with satisfactory results in a period of 68 days. Clinical and laboratory findings: according to the radiological and laboratory tests the animal developed a metacarpal bone osteomyelitis with periosteal reaction due to a beta-hemolytic Streptococcus Abscess. Conclusion: to our knowledge, this is the first report of medical procedures in this species. The most relevant findings and treatment schedule are discussed.  Key words: antimicrobial therapy, cervid, post-traumatic Abscess. Resumen Anamnesis y aproximacion terapeutica: una hembra de venado soche (Mazama americana), que presento un absceso postraumatico en la articulacion carpo-metacarpiana del miembro anterior izquierdo fue tratada con enrofloxacina (5 mg/kg) e ivermectina (0,2 mg/kg), sin responder al tratamiento. Se sometio a dos procedimientos quirurgicos con el fin de extraer el material purulento y realizar una antisepsia adecuada, ademas de varias terapias antibioticas, con resultados satisfactorios en un termino de 68 dias . Hallazgos clinicos y de laboratorio: de acuerdo a los resultados radiologicos y de laboratorio el animal desarrollo osteomielitis con reaccion periostica metacarpiana, debido a un absceso por Streptococcus beta-hemolitico. Conclusion: este es el primer reporte sobre procedimientos medicos en esta especie, se discuten los hallazgos clinicos y el esquema de tratamiento mas relevante.  Palabras clave: absceso postraumatico, cervido, terapia antimicrobiana. Resumo Historia e tratamento : uma femea de veado ( Mazama americana ) apresentou um Abscesso postraumatico na articulacao do carpo-metacarpo do membro esquerdo. Foi tratada com enrofloxacino (5 mg/kg) e ivermectina (0,2 mg/kg), sem responder ao tratamento. Logo foi submetida a dois procedimentos cirurgicos para remover o pus e fazer limpeza com antisseptico apropriado, alem de varias terapias antibioticas, com resultados satisfatorios em um periodo de 68 dias. Resultados clinicos e laboratoriais : de acordo com os resultados dos exames radiologicos e de laboratorio, o animal desenvolveu osteomielite no metacarpo com reacao periosteal devido a um Abscesso por Streptococcus beta-hemolitico. Conclusao: este e o primeiro relatorio sobre procedimentos medicos nesta especie, discutimos os achados clinicos e o sistema de tratamento adequado.  Palavras chave: Abscesso pos-traumatico, cervideo, terapia antimicrobiana.