The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
Hl Sithole - One of the best experts on this subject based on the ideXlab platform.
-
The ocular complications of an envenomous snakebite
Medpharm Publications Pty Ltd, 2013Co-Authors: Hl SitholeAbstract:An envenomous snakebite is an important public health problem that can lead to irreversible loss of vision. Snake venom neurotoxins mainly act on the peripheral nervous system at the neuromuscular junction, and result in the implication of the cranial nerves. Consequently, mild neurological symptoms that relate to cephalic muscle Paralysis, including exotropia, ptosis, diplopia and ophthalmoplegia, can occur. This happens because the extraocular muscles are especially susceptible to neurological muscular blockage. Other neurological complications of snake venom include Accommodation Paralysis, optic neuritis, globe necrosis, keratomalacia, uveitis, and loss of vision due to cortical infarction. Haemostatic complications may include subconjuctival haemorrhage, hyphema, and vitreous and retinal haemorrhages. Another rare complication of a snakebite is ocular injury. Snakebite injuries are often accompanied by facial swelling, periorbital ecchymosis, massive subconjuctival haemorrhage, severe corneal oedema and exophthalmos in the affected eye. Unfortunately, such injuries result in permanent loss of vision, as early evisceration is deemed necessary to reduce the amount and effect of the venom in the affected eye. With such a variety of ocular complications as a result of a venomous snakebite, it is important for primary care physicians to have some basic knowledge of the management of these complications, as they may prove to be vital where patients present with a snakebite and possible venom injection in the eye.Keywords: snakebite, venom, ocular complications, public healt
Michael Wolzt - One of the best experts on this subject based on the ideXlab platform.
-
a comparison between laser interferometric measurement of fundus pulsation and pneumotonometric measurement of pulsatile ocular blood flow 1 baseline considerations
Eye, 2000Co-Authors: Leopold Schmetterer, Susanne Dallinger, Oliver Findl, Hansgeorg Eichler, Michael WolztAbstract:PURPOSE Several methods have been proposed for the investigation of the human choroidal circulation. The aim of the present study was to compare laser interferometric measurements of cardiac synchronous fundus pulsations with pneumotonometric measurements of intraocular pressure pulse and pulsatile ocular blood flow in humans. METHODS The association between fundus pulsation amplitude as assessed with laser interferometry and pulse amplitude (PA) and pulsatile ocular blood flow (POBF) as assessed with pneumotonometry was investigated in 28 healthy subjects. Additionally, we investigated the distribution of fundus pulsation amplitude (FPA) in a region of -15 degrees to +15 degrees around the macula (n = 18) and the influence of Accommodation Paralysis with cyclopentolate on FPA (n = 10). RESULTS There was a high association between FPA and PA (r = 0.86, p < 0.001) and FPA and POBF (r = 0.70, p < 0.001). Fundus pulsations in the macula were significantly smaller than in the optic disc, but significantly larger than those in peripheral regions of the retina. Administration of cyclopentolate did not influence FPA. CONCLUSIONS On the basis of the strong correlation between laser interferometric measurements of FPA and pneumotonometric measurements of PA and POBF, we conclude that the FPA is a valid index of pulsatile choroidal perfusion in humans.
F. Nilüfer Yalçındağ - One of the best experts on this subject based on the ideXlab platform.
-
Accommodation Paralysis after Pheniramine Maleate Injection: A Case Report.
Neuro-Ophthalmology, 2013Co-Authors: Pınar Bingöl Kızıltunç, Huban Atilla, F. Nilüfer YalçındağAbstract:We present a case in which Gilbert syndrome was diagnosed following a neuro-ophthalmic complaint. Adverse effects of drugs as well as various systemic, neurological, and local ocular pathologies can cause accommodative insufficiency and loss of Accommodation. A 29-year-old man was admitted to an ophthalmology department with blurred vision and diagnosed as suffering from acute Accommodation Paralysis. He had a history of being given a pheniramine maleate injection for pruritus 20 days previously. Symptoms began immediately following the injection. After systemic evaluation and laboratory tests, he was diagnosed as having Gilbert syndrome. His complaints and symptoms recovered in approximately a further 10 days. Metabolism of pheniramine maleate can be impaired in Gilbert syndrome and anticholinergic effects can cause Accommodation Paralysis.
University Of Lausanne - One of the best experts on this subject based on the ideXlab platform.
-
Walsh & Hoyt: Accommodation Insufficiency and Paralysis
Spencer S. Eccles Health Sciences Library University of Utah, 2005Co-Authors: Aki Kawasaki, Faculty Of Biology And Medicine, University Of LausanneAbstract:Congenital and hereditary Accommodation. Insufficiency and Paralysis. Congenital defects are a rare cause of isolated Accommodation insufficiency. The ciliary body is defective in a number of congenital ocular anomalies, but in most cases vision is so defective that an inability to accommodate is never noted by either the patient or the physician. Aniridia and choroidal coloboma cause obvious defects of the ciliary body. Ciliary aplasia can occur in well-formed eyes in which the iris is intact and reacts normally to light. Acquired Accommodation paresis. Isolated Accommodation insufficiency. Accommodation insufficiency associated with primary ocular disease. Accommodation insufficiency associated with neuromuscular disorders. Accommodation insufficiency associated with focal or generalized neurologic disease. Accommodation insufficiency associated with systemic disease. Accommodation insufficiency associated with trauma to the head and neck. Accommodation insufficiency and Paralysis from pharmacologic agents. Accommodation Paralysis for distance: sympathetic Paralysis
Leopold Schmetterer - One of the best experts on this subject based on the ideXlab platform.
-
a comparison between laser interferometric measurement of fundus pulsation and pneumotonometric measurement of pulsatile ocular blood flow 1 baseline considerations
Eye, 2000Co-Authors: Leopold Schmetterer, Susanne Dallinger, Oliver Findl, Hansgeorg Eichler, Michael WolztAbstract:PURPOSE Several methods have been proposed for the investigation of the human choroidal circulation. The aim of the present study was to compare laser interferometric measurements of cardiac synchronous fundus pulsations with pneumotonometric measurements of intraocular pressure pulse and pulsatile ocular blood flow in humans. METHODS The association between fundus pulsation amplitude as assessed with laser interferometry and pulse amplitude (PA) and pulsatile ocular blood flow (POBF) as assessed with pneumotonometry was investigated in 28 healthy subjects. Additionally, we investigated the distribution of fundus pulsation amplitude (FPA) in a region of -15 degrees to +15 degrees around the macula (n = 18) and the influence of Accommodation Paralysis with cyclopentolate on FPA (n = 10). RESULTS There was a high association between FPA and PA (r = 0.86, p < 0.001) and FPA and POBF (r = 0.70, p < 0.001). Fundus pulsations in the macula were significantly smaller than in the optic disc, but significantly larger than those in peripheral regions of the retina. Administration of cyclopentolate did not influence FPA. CONCLUSIONS On the basis of the strong correlation between laser interferometric measurements of FPA and pneumotonometric measurements of PA and POBF, we conclude that the FPA is a valid index of pulsatile choroidal perfusion in humans.
