The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
Melanie S Sanford - One of the best experts on this subject based on the ideXlab platform.
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palladium catalyzed c h bond Acetoxylation via electrochemical oxidation
Organic Letters, 2018Co-Authors: Anuska Shrestha, Anna L Dunn, Melanie S SanfordAbstract:Here we describe the development of a method for the Pd-catalyzed electrochemical Acetoxylation of C–H bonds. The oxidation step of the catalytic cycle is probed through cyclic voltammetry and bulk electrolysis studies of a preformed palladacycle of 8-methylquinoline. A catalytic system for C–H Acetoxylation is then developed and optimized with respect to the cell configuration, rate of oxidation, and chemistry at the counter electrode. This transformation is then applied to substrates containing various directing groups and to the Acetoxylation of both C(sp2)–H and C(sp3)–H bonds.
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steric control of site selectivity in the pd catalyzed c h Acetoxylation of simple arenes
ChemInform, 2014Co-Authors: Amanda K Cook, Marion H Emmert, Melanie S SanfordAbstract:Pd-catalyzed oxidative Acetoxylation of benzenes is studied using hypervalent iodine acetates.
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Steric Control of Site Selectivity in the Pd‐Catalyzed C—H Acetoxylation of Simple Arenes.
ChemInform, 2014Co-Authors: Amanda K Cook, Marion H Emmert, Melanie S SanfordAbstract:Pd-catalyzed oxidative Acetoxylation of benzenes is studied using hypervalent iodine acetates.
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steric control of site selectivity in the pd catalyzed c h Acetoxylation of simple arenes
Organic Letters, 2013Co-Authors: Amanda K Cook, Marion H Emmert, Melanie S SanfordAbstract:This report describes the use of an oxidant and a ligand to control site selectivity in the Pd(OAc)2-catalyzed C–H Acetoxylation of simple arenes. The use of MesI(OAc)2 as the terminal oxidant in combination with acridine as the ligand results in primarily sterically controlled selectivity. In contrast, with Pd(OAc)2 as the catalyst and PhI(OAc)2 as the oxidant, electronic effects dominate the selectivity of arene C–H Acetoxylation.
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mechanistic comparison between pd catalyzed ligand directed c h chlorination and c h Acetoxylation
Organic Letters, 2009Co-Authors: Kara J Stowers, Melanie S SanfordAbstract:This communication describes detailed investigations of the mechanism of the Pd-catalyzed C−H chlorination and Acetoxylation of 2-o-tolylpyridine. Under the conditions examined, both reactions proceed via rate-limiting cyclopalladation. However, substrate and catalyst order as well as Hammett data indicate that the intimate mechanism of cyclopalladation differs significantly between PdCl2-catalyzed chlorination and Pd(OAc)2-catalyzed Acetoxylation.
J S Yadav - One of the best experts on this subject based on the ideXlab platform.
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quinazolinone directed c h activation a novel strategy for the Acetoxylation methoxylation of the arenes
Synlett, 2012Co-Authors: B Subba V Reddy, G Narasimhulu, N Umadevi, J S YadavAbstract:2-Aryl-4-quinazolinones undergo smooth Acetoxylation in the presence of 5 mol% Pd(OAc)2 and a stoichiometric amount of PhI(OAc)2 via C–H activation to produce the corresponding acetoxy-substituted 4(3H)-quinazolinone derivatives in good yields with high regioselectivity.
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first example of quinoxaline directed c h activation a novel method for Acetoxylation of arenes
Synlett, 2011Co-Authors: B V S Reddy, K. Ramesh, J S YadavAbstract:2-Aryl- and 2,3-diarylquinoxalines undergo smooth Acetoxylation in the presence of 5 mol% Pd(OAc) 2 and a stoichiometric amount of PhI(OAc) 2 via C―H activation to produce the corresponding acetoxy-susbstituted quinoxaline derivatives in excellent yields with high regioselectivity.
Bing Zhou - One of the best experts on this subject based on the ideXlab platform.
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rhodium iii catalyzed selective c h Acetoxylation and hydroxylation reactions
Organic Letters, 2017Co-Authors: Yunxiang Wu, Bing ZhouAbstract:An efficient Cp*Rh(III)-catalyzed, chelation-assisted C(sp2)–H Acetoxylation and hydroxylation reaction has been developed for the first time. The reaction proceeds under mild conditions and allows for selective preparation of C–H Acetoxylation and hydroxylation products, thus providing a good complement to previous C–H oxygenation reactions and expanding the field of Cp*Rh(III)-catalyzed C–H functionalizations.
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Rhodium(III)-Catalyzed Selective C–H Acetoxylation and Hydroxylation Reactions
Organic Letters, 2017Co-Authors: Yunxiang Wu, Bing ZhouAbstract:An efficient Cp*Rh(III)-catalyzed, chelation-assisted C(sp2)–H Acetoxylation and hydroxylation reaction has been developed for the first time. The reaction proceeds under mild conditions and allows for selective preparation of C–H Acetoxylation and hydroxylation products, thus providing a good complement to previous C–H oxygenation reactions and expanding the field of Cp*Rh(III)-catalyzed C–H functionalizations.
Yuhong Zhang - One of the best experts on this subject based on the ideXlab platform.
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amide assisted Acetoxylation of vinyl c sp2 h bonds by rhodium catalysis
ChemInform, 2015Co-Authors: Wenlong Yu, Jia Chen, Yuhong ZhangAbstract:The first rhodium-catalyzed Acetoxylation of an olefinic C—H bond in enamides proceeds with high regio- and stereoselectivity to give Z-configurated products.
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amide assisted Acetoxylation of vinyl c sp2 h bonds by rhodium catalysis
Organic Letters, 2014Co-Authors: Wenlong Yu, Jia Chen, Yuhong ZhangAbstract:A direct regioselective Acetoxylation of enamides has been accomplished using a combination of Cu(OAc)2 and rhodium catalyst. Cu(OAc)2 is served as the oxidant and also provides the source of acetate in the reaction.
Yunxiang Wu - One of the best experts on this subject based on the ideXlab platform.
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rhodium iii catalyzed selective c h Acetoxylation and hydroxylation reactions
Organic Letters, 2017Co-Authors: Yunxiang Wu, Bing ZhouAbstract:An efficient Cp*Rh(III)-catalyzed, chelation-assisted C(sp2)–H Acetoxylation and hydroxylation reaction has been developed for the first time. The reaction proceeds under mild conditions and allows for selective preparation of C–H Acetoxylation and hydroxylation products, thus providing a good complement to previous C–H oxygenation reactions and expanding the field of Cp*Rh(III)-catalyzed C–H functionalizations.
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Rhodium(III)-Catalyzed Selective C–H Acetoxylation and Hydroxylation Reactions
Organic Letters, 2017Co-Authors: Yunxiang Wu, Bing ZhouAbstract:An efficient Cp*Rh(III)-catalyzed, chelation-assisted C(sp2)–H Acetoxylation and hydroxylation reaction has been developed for the first time. The reaction proceeds under mild conditions and allows for selective preparation of C–H Acetoxylation and hydroxylation products, thus providing a good complement to previous C–H oxygenation reactions and expanding the field of Cp*Rh(III)-catalyzed C–H functionalizations.