The Experts below are selected from a list of 48624 Experts worldwide ranked by ideXlab platform

Jennifer L. Roizen - One of the best experts on this subject based on the ideXlab platform.

Zhaoyin Wang - One of the best experts on this subject based on the ideXlab platform.

David Milstein - One of the best experts on this subject based on the ideXlab platform.

  • General Synthesis of Amino Acid Salts from Amino Alcohols and Basic Water Liberating H2
    Journal of the American Chemical Society, 2016
    Co-Authors: Yehoshoa Ben-david, David Milstein
    Abstract:

    An atom-economical and environmentally friendly method to transform amino alcohols to amino Acid Salts using just basic water, without the need of pre-protection or added oxidant, catalyzed by a ruthenium pincer complex, is developed. Water is the solvent, the source of the oxygen atom of the carboxylic Acid group, and the actual oxidant, with liberation of dihydrogen. Many important and useful natural and unnatural amino Acid Salts can be produced in excellent yields by applying this new method.

  • catalytic transformation of alcohols to carboxylic Acid Salts and h2 using water as the oxygen atom source
    Nature Chemistry, 2013
    Co-Authors: Eugene Khaskin, Ekambaram Balaraman, Gregory Leitus, David Milstein
    Abstract:

    The development of a catalytic, mild and atom-economical transformation of alcohols to carboxylic Acid Salts and hydrogen gas is described. The reaction uses water as a source of oxygen, with a homogenous Ru catalyst at low (0.2 mol%) catalyst loadings in basic aqueous solution.

  • Catalytic transformation of alcohols to carboxylic Acid Salts and H_2 using water as the oxygen atom source
    Nature Chemistry, 2013
    Co-Authors: Ekambaram Balaraman, Eugene Khaskin, Gregory Leitus, David Milstein
    Abstract:

    The oxidation of alcohols to carboxylic Acids is an important industrial reaction used in the synthesis of bulk and fine chemicals. Most current processes are performed by making use of either stoichiometric amounts of toxic oxidizing agents or the use of pressurized dioxygen. Here, we describe an alternative dehydrogenative pathway effected by water and base with the concomitant generation of hydrogen gas. A homogeneous ruthenium complex catalyses the transformation of primary alcohols to carboxylic Acid Salts at low catalyst loadings (0.2 mol%) in basic aqueous solution. A consequence of this finding could be a safer and cleaner process for the synthesis of carboxylic Acids and their derivatives at both laboratory and industrial scales. The development of a catalytic, mild and atom-economical transformation of alcohols to carboxylic Acid Salts and hydrogen gas is described. The reaction uses water as a source of oxygen, with a homogenous Ru catalyst at low (0.2 mol%) catalyst loadings in basic aqueous solution.

J. Miles Blackburn - One of the best experts on this subject based on the ideXlab platform.

Melanie A. Short - One of the best experts on this subject based on the ideXlab platform.