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Uchechukwu C Megwalu - One of the best experts on this subject based on the ideXlab platform.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2021Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:OBJECTIVES To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. METHODS This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. RESULTS The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. CONCLUSION Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. LEVEL OF EVIDENCE 3 Laryngoscope, 131:E1125-E1129, 2021.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2020Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:Objectives To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. Methods This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. Results The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. Conclusion Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. Level of evidence 3 Laryngoscope, 2020.
Peter Moon - One of the best experts on this subject based on the ideXlab platform.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2021Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:OBJECTIVES To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. METHODS This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. RESULTS The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. CONCLUSION Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. LEVEL OF EVIDENCE 3 Laryngoscope, 131:E1125-E1129, 2021.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2020Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:Objectives To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. Methods This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. Results The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. Conclusion Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. Level of evidence 3 Laryngoscope, 2020.
Mahbuba Tusty - One of the best experts on this subject based on the ideXlab platform.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2021Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:OBJECTIVES To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. METHODS This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. RESULTS The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. CONCLUSION Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. LEVEL OF EVIDENCE 3 Laryngoscope, 131:E1125-E1129, 2021.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2020Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:Objectives To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. Methods This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. Results The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. Conclusion Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. Level of evidence 3 Laryngoscope, 2020.
Vasu Divi - One of the best experts on this subject based on the ideXlab platform.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2021Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:OBJECTIVES To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. METHODS This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. RESULTS The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. CONCLUSION Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. LEVEL OF EVIDENCE 3 Laryngoscope, 131:E1125-E1129, 2021.
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significance of nodal metastasis in parotid gland Acinar Cell Carcinoma
Laryngoscope, 2020Co-Authors: Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C MegwaluAbstract:Objectives To evaluate the rate of lymph node metastasis in parotid gland Acinar Cell Carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. Methods This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) 18 database. The study cohort included patients with parotid gland Acinar Cell Carcinoma diagnosed between 2000 and 2015. Results The overall rate of lymph node metastasis was 6.8%. T3/T4 (OR 6.17, 95% CI, 3.03 to 13.16) disease along with High Grade (OR 15.95) disease were associated with increased risk of nodal metastasis. Non-white, non-Black race was associated with decreased risk. Age and sex were not associated with nodal metastasis. Nodal metastasis was associated with worse OS (HR 6.27, 95% CI, 3.85 to 10.20) and DSS (HR 6.96, 95% CI, 3.81 to 12.73) after adjusting for covariates. Conclusion Parotid gland Acinar Cell Carcinoma carries a low risk of nodal metastasis. Both advanced T stage and high grade are associated with increased risk of nodal metastasis. Nodal metastasis is associated with decreased overall survival. Level of evidence 3 Laryngoscope, 2020.
Shoki Takahashi - One of the best experts on this subject based on the ideXlab platform.
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two cases of 18 f fdg pet ct findings in Acinar Cell Carcinoma of the pancreas
Clinical Nuclear Medicine, 2009Co-Authors: Kentaro Takanami, Keiko Abe, Atsushi Mitamura, Shukichi Miyazaki, Kazuyuki Ishida, Shogo Yamada, Shoki TakahashiAbstract:The patients consisted of a 60-year-old woman and a 72-year-old man with no significant symptoms, who were both referred to the hospital due to the presence of large pancreatic tumors. They underwent F-18 FDG PET/CT and subsequently a pancreaticoduodenectomy and Acinar Cell Carcinoma in the pancreas was proven histopathologically. In one case, the tumor consisted of a solid component presenting intense FDG uptake and necrotic tissue. In another case, the tumor consisted of cystic and papillary components presenting with weak FDG uptake. This report thus documents 2 cases of Acinar Cell Carcinoma that showed contrasting histopathologic and F-18 FDG PET/CT findings.
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Two cases of 18 F-FDG PET/CT findings in Acinar Cell Carcinoma of the pancreas.
Clinical nuclear medicine, 2009Co-Authors: Kentaro Takanami, Keiko Abe, Atsushi Mitamura, Shukichi Miyazaki, Kazuyuki Ishida, Shogo Yamada, Shoki TakahashiAbstract:The patients consisted of a 60-year-old woman and a 72-year-old man with no significant symptoms, who were both referred to the hospital due to the presence of large pancreatic tumors. They underwent F-18 FDG PET/CT and subsequently a pancreaticoduodenectomy and Acinar Cell Carcinoma in the pancreas was proven histopathologically. In one case, the tumor consisted of a solid component presenting intense FDG uptake and necrotic tissue. In another case, the tumor consisted of cystic and papillary components presenting with weak FDG uptake. This report thus documents 2 cases of Acinar Cell Carcinoma that showed contrasting histopathologic and F-18 FDG PET/CT findings.
