The Experts below are selected from a list of 735 Experts worldwide ranked by ideXlab platform
Fumihiko Kanai - One of the best experts on this subject based on the ideXlab platform.
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asymmetric diels alder reactions of an Acrylic Acid Derivative using a chiral titanium catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
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Asymmetric Diels–Alder Reactions of an Acrylic Acid Derivative Using a Chiral Titanium Catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
Koichi Narasaka - One of the best experts on this subject based on the ideXlab platform.
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asymmetric diels alder reactions of an Acrylic Acid Derivative using a chiral titanium catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
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Asymmetric Diels–Alder Reactions of an Acrylic Acid Derivative Using a Chiral Titanium Catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
Hiroko Tanaka - One of the best experts on this subject based on the ideXlab platform.
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asymmetric diels alder reactions of an Acrylic Acid Derivative using a chiral titanium catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
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Asymmetric Diels–Alder Reactions of an Acrylic Acid Derivative Using a Chiral Titanium Catalyst
Bulletin of the Chemical Society of Japan, 1991Co-Authors: Koichi Narasaka, Hiroko Tanaka, Fumihiko KanaiAbstract:Asymmetric Diels–Alder reactions of an Acrylic Acid Derivative using a catalytic amount of a chiral titanium reagent were performed with several dienes. The titanium catalyst was prepared by the al...
Pavel K. Mykhailiuk - One of the best experts on this subject based on the ideXlab platform.
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Photochemical In-Flow Synthesis of 2,4-Methanopyrrolidines: Pyrrolidine Analogues with Improved Water Solubility and Reduced Lipophilicity
The Journal of Organic Chemistry, 2018Co-Authors: Vadym V. Levterov, Oleg M. Michurin, Petro Borysko, Sergey Zozulya, Iryna V. Sadkova, Andrey A. Tolmachev, Pavel K. MykhailiukAbstract:A practical synthesis of 2,4-methanopyrrolidines was elaborated. The key synthetic step was an intramolecular photochemical [2 + 2]-cycloaddition of an Acrylic Acid Derivative in flow. In spite of a higher molecular weight, 2,4-methanopyrrolidines were shown to have higher solubility in water and lower lipophilicity than pyrrolidines, important characteristics of bioactive molecules in drug design.
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Photochemical In-Flow Synthesis of 2,4-Methanopyrrolidines: Pyrrolidine Analogues with Improved Water Solubility and Reduced Lipophilicity
2018Co-Authors: Vadym V. Levterov, Oleg M. Michurin, Petro Borysko, Sergey Zozulya, Iryna V. Sadkova, Andrey A. Tolmachev, Pavel K. MykhailiukAbstract:A practical synthesis of 2,4-methanopyrrolidines was elaborated. The key synthetic step was an intramolecular photochemical [2 + 2]-cycloaddition of an Acrylic Acid Derivative in flow. In spite of a higher molecular weight, 2,4-methanopyrrolidines were shown to have higher solubility in water and lower lipophilicity than pyrrolidines, important characteristics of bioactive molecules in drug design
Faruk Nome - One of the best experts on this subject based on the ideXlab platform.
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Supramolecular Polymer/Surfactant Complexes as Catalysts for Phosphate Transfer Reactions
2017Co-Authors: Adriana P. Gerola, Eduardo H. Wanderlind, Yasmin S. Gomes, Luciano A. Giusti, Luis García-río, René A. Nome, Anthony J. Kirby, Haidi D. Fiedler, Faruk NomeAbstract:Designing artificial enzymes with tailored molecular interactions between the substrate and active site is of major intellectual and practical significance. We report the improved catalytic efficiency of a supramolecular polymer/surfactant complex comprised of PAIM–, a poly(Acrylic Acid) Derivative with imidazole groups attached to the polymer by amide bonds, and the cationic surfactant cetyltrimethylammonium bromide (CTAB). Supramolecular complex formation, at concentrations below the respective CMC values, provides convenient hydrophobic pockets for the reactants close to the multiple catalytic centers, where imidazole and carboxylate groups act as nucleophiles for the degradation of a model phosphate triester, delivering the highly efficient performance of the supramolecular catalysts. Catalytic effects are on the order of thousands for nucleophilic catalysis and are higher by 2 orders of magnitude for the supramolecular polymer/surfactant complex at pH 9. The reported supramolecular catalytic complexes allow important changes in polarity and, given the presence of functional groups common to a variety of hydrolytic enzymes, could be of general applicability in such reactions
