The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Danny Bluestein - One of the best experts on this subject based on the ideXlab platform.
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flow induced platelet Activation in a st jude mechanical heart valve a trileaflet polymeric heart valve and a st jude tissue valve
Artificial Organs, 2005Co-Authors: Wei Yin, Siobhain Lynn Gallocher, Leonard Pinchuk, Richard T Schoephoerster, Jolyon Jesty, Danny BluesteinAbstract:Polymer heart valves have been under investigation since the 1960s, but their success has been hampered by an overall lack of durability mainly due to calcification of the leaflets and a relatively high rate of thromboembolic complications. A new polymer (Quatromer) trileaflet design was tested for its thrombogenic potential and was compared to that of existing prosthetic heart valves routinely implanted in patients: a St. Jude Medical bileaflet mechanical heart valve (MHV) and a St. Jude porcine bioprosthetic tissue valve. The valves were mounted in a left ventricular assist device and the procoagulant activity of the platelets was measured using a platelet Activation state (PAS) assay. The PAS measurements indicated that the platelet Activation Level induced by the polymeric valve was very similar to that induced by the St. Jude Medical MHV and the St. Jude tissue valve. No significant difference was observed between the three valves, indicating that they have a comparable thrombogenic potential.
Wei Yin - One of the best experts on this subject based on the ideXlab platform.
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flow induced platelet Activation in a st jude mechanical heart valve a trileaflet polymeric heart valve and a st jude tissue valve
Artificial Organs, 2005Co-Authors: Wei Yin, Siobhain Lynn Gallocher, Leonard Pinchuk, Richard T Schoephoerster, Jolyon Jesty, Danny BluesteinAbstract:Polymer heart valves have been under investigation since the 1960s, but their success has been hampered by an overall lack of durability mainly due to calcification of the leaflets and a relatively high rate of thromboembolic complications. A new polymer (Quatromer) trileaflet design was tested for its thrombogenic potential and was compared to that of existing prosthetic heart valves routinely implanted in patients: a St. Jude Medical bileaflet mechanical heart valve (MHV) and a St. Jude porcine bioprosthetic tissue valve. The valves were mounted in a left ventricular assist device and the procoagulant activity of the platelets was measured using a platelet Activation state (PAS) assay. The PAS measurements indicated that the platelet Activation Level induced by the polymeric valve was very similar to that induced by the St. Jude Medical MHV and the St. Jude tissue valve. No significant difference was observed between the three valves, indicating that they have a comparable thrombogenic potential.
Marcus J. Schultz - One of the best experts on this subject based on the ideXlab platform.
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usefulness of supar as a biological marker in patients with systemic inflammation or infection a systematic review
Intensive Care Medicine, 2012Co-Authors: David P Mackie, Koenraad F. Van Der Sluijs, Yara Backes, Jyrki Tenhunen, Frank Tacke, Alexander Koch, Marcus J. SchultzAbstract:Purpose Systemic Levels of soluble urokinase-type plasminogen activator receptor (suPAR) positively correlate with the Activation Level of the immune system. We reviewed the usefulness of systemic Levels of suPAR in the care of critically ill patients with sepsis, SIRS, and bacteremia, focusing on its diagnostic and prognostic value.
Richard T Schoephoerster - One of the best experts on this subject based on the ideXlab platform.
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flow induced platelet Activation in a st jude mechanical heart valve a trileaflet polymeric heart valve and a st jude tissue valve
Artificial Organs, 2005Co-Authors: Wei Yin, Siobhain Lynn Gallocher, Leonard Pinchuk, Richard T Schoephoerster, Jolyon Jesty, Danny BluesteinAbstract:Polymer heart valves have been under investigation since the 1960s, but their success has been hampered by an overall lack of durability mainly due to calcification of the leaflets and a relatively high rate of thromboembolic complications. A new polymer (Quatromer) trileaflet design was tested for its thrombogenic potential and was compared to that of existing prosthetic heart valves routinely implanted in patients: a St. Jude Medical bileaflet mechanical heart valve (MHV) and a St. Jude porcine bioprosthetic tissue valve. The valves were mounted in a left ventricular assist device and the procoagulant activity of the platelets was measured using a platelet Activation state (PAS) assay. The PAS measurements indicated that the platelet Activation Level induced by the polymeric valve was very similar to that induced by the St. Jude Medical MHV and the St. Jude tissue valve. No significant difference was observed between the three valves, indicating that they have a comparable thrombogenic potential.
Siobhain Lynn Gallocher - One of the best experts on this subject based on the ideXlab platform.
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flow induced platelet Activation in a st jude mechanical heart valve a trileaflet polymeric heart valve and a st jude tissue valve
Artificial Organs, 2005Co-Authors: Wei Yin, Siobhain Lynn Gallocher, Leonard Pinchuk, Richard T Schoephoerster, Jolyon Jesty, Danny BluesteinAbstract:Polymer heart valves have been under investigation since the 1960s, but their success has been hampered by an overall lack of durability mainly due to calcification of the leaflets and a relatively high rate of thromboembolic complications. A new polymer (Quatromer) trileaflet design was tested for its thrombogenic potential and was compared to that of existing prosthetic heart valves routinely implanted in patients: a St. Jude Medical bileaflet mechanical heart valve (MHV) and a St. Jude porcine bioprosthetic tissue valve. The valves were mounted in a left ventricular assist device and the procoagulant activity of the platelets was measured using a platelet Activation state (PAS) assay. The PAS measurements indicated that the platelet Activation Level induced by the polymeric valve was very similar to that induced by the St. Jude Medical MHV and the St. Jude tissue valve. No significant difference was observed between the three valves, indicating that they have a comparable thrombogenic potential.
