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Timo Koivula - One of the best experts on this subject based on the ideXlab platform.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain ( Lactobacillus casei sp strain GG , Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 wellnourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG -fermented milk product, 125 g (10 10-11 colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10 10-11 colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain (Lactobacillus casei sp strain GG, Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 well-nourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG-fermented milk product, 125 g (10(10-11) colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10(10-11) colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P less than 0.001. After rehydration, each dietary group maintained a positive weight trend. The urinary lactulose-mannitol recovery ratios (means [95% confidence intervals]) on admission were 0.09 (0.03, 0.24) in group 1, 0.12 (0.07, 0.22) in group 2, and 0.08 (0.04, 0.18) in group 3; no significant alterations in intestinal permeability were observed at retesting after 2 days of realimentation. The result indicates that early nutritional repletion after rehydration causes no mucosal disruption and is beneficial for recovery from Diarrhea. It is further suggested that Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

Erika Isolauri - One of the best experts on this subject based on the ideXlab platform.

  • lactobacillus reuteri as a therapeutic agent in Acute Diarrhea in young children
    Journal of Pediatric Gastroenterology and Nutrition, 1997
    Co-Authors: Ainovieno Shornikova, Erika Isolauri, Ivan A Casas, Hannu Mykkanen, Timo Vesikari
    Abstract:

    Background: Certain strains of lactobacilli may promote recovery from Acute Diarrhea. Lactobacillus reuteri is of human origin and is a natural colonizer of gastrointestinal tract. In this trial, exogenously administered L. reuteri was studied as a therapeutic agent in Acute Diarrhea. Methods: Forty patients between 6 and 36 months of age hospitalized with Acute Diarrhea (75% rotavirus) were studied. After parental consent, the patients were randomized to one of two treatment groups to receive either 10 10 to 10 11 colony-forming units of L. reuteri or a matching placebo daily for the length of hospitalization or up to 5 days. The clinical outcome of Diarrhea and colonization of L. reuteri were evaluated. Results: The mean (SD) duration of watery Diarrhea after treatment was 1.7 (1.6) days in the L. reuteri group and 2.9 (2.3) days in the placebo group (p = 0.07). On the second day of treatment only 26% of patients receiving L. reuteri had watery Diarrhea, compared with 81% of those receving placebo (p = 0.0005). Cultures of lactobacilli from stool samples demonstrated that administration of L. reuteri resulted in colonization of the gastrointestinal tract. Lactobacillus reuteri accounted for >75% of the total lactobacilli found in children fed with this product. Conclusions: Lactobacillus reuteri is effective as a therapeutic agent in Acute rotavirus Diarrhea in children. Further studies are warranted to confirm the present finding and to explore the full therapeutic potential of L. reuteri in Acute viral Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain ( Lactobacillus casei sp strain GG , Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 wellnourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG -fermented milk product, 125 g (10 10-11 colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10 10-11 colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain (Lactobacillus casei sp strain GG, Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 well-nourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG-fermented milk product, 125 g (10(10-11) colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10(10-11) colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P less than 0.001. After rehydration, each dietary group maintained a positive weight trend. The urinary lactulose-mannitol recovery ratios (means [95% confidence intervals]) on admission were 0.09 (0.03, 0.24) in group 1, 0.12 (0.07, 0.22) in group 2, and 0.08 (0.04, 0.18) in group 3; no significant alterations in intestinal permeability were observed at retesting after 2 days of realimentation. The result indicates that early nutritional repletion after rehydration causes no mucosal disruption and is beneficial for recovery from Diarrhea. It is further suggested that Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

Marianne Juntunen - One of the best experts on this subject based on the ideXlab platform.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain ( Lactobacillus casei sp strain GG , Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 wellnourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG -fermented milk product, 125 g (10 10-11 colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10 10-11 colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain (Lactobacillus casei sp strain GG, Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 well-nourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG-fermented milk product, 125 g (10(10-11) colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10(10-11) colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P less than 0.001. After rehydration, each dietary group maintained a positive weight trend. The urinary lactulose-mannitol recovery ratios (means [95% confidence intervals]) on admission were 0.09 (0.03, 0.24) in group 1, 0.12 (0.07, 0.22) in group 2, and 0.08 (0.04, 0.18) in group 3; no significant alterations in intestinal permeability were observed at retesting after 2 days of realimentation. The result indicates that early nutritional repletion after rehydration causes no mucosal disruption and is beneficial for recovery from Diarrhea. It is further suggested that Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

Pekka Sillanaukee - One of the best experts on this subject based on the ideXlab platform.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain ( Lactobacillus casei sp strain GG , Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 wellnourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG -fermented milk product, 125 g (10 10-11 colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10 10-11 colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain (Lactobacillus casei sp strain GG, Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 well-nourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG-fermented milk product, 125 g (10(10-11) colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10(10-11) colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P less than 0.001. After rehydration, each dietary group maintained a positive weight trend. The urinary lactulose-mannitol recovery ratios (means [95% confidence intervals]) on admission were 0.09 (0.03, 0.24) in group 1, 0.12 (0.07, 0.22) in group 2, and 0.08 (0.04, 0.18) in group 3; no significant alterations in intestinal permeability were observed at retesting after 2 days of realimentation. The result indicates that early nutritional repletion after rehydration causes no mucosal disruption and is beneficial for recovery from Diarrhea. It is further suggested that Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

Tarja Rautanen - One of the best experts on this subject based on the ideXlab platform.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain ( Lactobacillus casei sp strain GG , Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 wellnourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG -fermented milk product, 125 g (10 10-11 colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10 10-11 colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.

  • a human lactobacillus strain lactobacillus casei sp strain gg promotes recovery from Acute Diarrhea in children
    Pediatrics, 1991
    Co-Authors: Erika Isolauri, Marianne Juntunen, Tarja Rautanen, Pekka Sillanaukee, Timo Koivula
    Abstract:

    To determine the effect of a human Lactobacillus strain (Lactobacillus casei sp strain GG, Gefilac) on recovery from Acute Diarrhea (82% rotavirus), 71 well-nourished children between 4 and 45 months of age were studied. After oral rehydration, the patients randomly received either Lactobacillus GG-fermented milk product, 125 g (10(10-11) colony-forming units) twice daily (group 1); Lactobacillus GG freeze-dried powder, one dose (10(10-11) colony-forming units) twice daily (group 2); or a placebo, a pasteurized yogurt (group 3) 125 g twice daily; each diet was given for 5 days, in addition to normal full diet otherwise free of fermented dairy products. The mean (SD) duration of Diarrhea after commencing the therapy was significantly shorter in group 1 (1.4 [0.8] days) and in group 2 (1.4 [0.8] days) than in group 3 (2.4 [1.1] days); F = 8.70, P less than 0.001. After rehydration, each dietary group maintained a positive weight trend. The urinary lactulose-mannitol recovery ratios (means [95% confidence intervals]) on admission were 0.09 (0.03, 0.24) in group 1, 0.12 (0.07, 0.22) in group 2, and 0.08 (0.04, 0.18) in group 3; no significant alterations in intestinal permeability were observed at retesting after 2 days of realimentation. The result indicates that early nutritional repletion after rehydration causes no mucosal disruption and is beneficial for recovery from Diarrhea. It is further suggested that Lactobacillus GG in the form of fermented milk or freeze-dried powder is effective in shortening the course of Acute Diarrhea.