The Experts below are selected from a list of 15420 Experts worldwide ranked by ideXlab platform

Loren Cordain - One of the best experts on this subject based on the ideXlab platform.

  • cardiovascular disease resulting from a diet and lifestyle at odds with our paleolithic genome how to become a 21st century hunter gatherer
    Mayo Clinic Proceedings, 2004
    Co-Authors: James H Okeefe, Loren Cordain
    Abstract:

    Our genetic make-up, shaped through millions of years of evolution, determines our nutritional and activity needs. Although the human genome has remained primarily unchanged since the Agricultural Revolution 10,000 years ago, our diet and lifestyle have become progressively more divergent from those of our ancient ancestors. Accumulating evidence suggests that this mismatch between our modern diet and lifestyle and our Paleolithic genome is playing a substantial role in the ongoing epidemics of obesity, hypertension, diabetes, and atherosclerotic cardiovascular disease. Until 500 generations ago, all humans consumed only wild and unprocessed food foraged and hunted from their environment. These circumstances provided a diet high in lean protein, polyunsaturated fats (especially omega-3 [ω-3] fatty acids), monounsaturated fats, fiber, vitamins, minerals, antioxidants, and other beneficial phytochemicals. Historical and anthropological studies show hunter-gatherers generally to be healthy, fit, and largely free of the degenerative cardiovascular diseases common in modern societies. This review outlines the essence of our hunter-gatherer genetic legacy and suggests practical steps to realign our modern milieu with our ancient genome in an effort to improve cardiovascular health.

  • cardiovascular disease resulting from a diet and lifestyle at odds with our paleolithic genome how to become a 21st century hunter gatherer
    Mayo Clinic Proceedings, 2004
    Co-Authors: James H Okeefe, Loren Cordain
    Abstract:

    Our genetic make-up, shaped through millions of years of evolution, determines our nutritional and activity needs. Although the human genome has remained primarily unchanged since the Agricultural Revolution 10,000 years ago, our diet and lifestyle have become progressively more divergent from those of our ancient ancestors. Accumulating evidence suggests that this mismatch between our modern diet and lifestyle and our Paleolithic genome is playing a substantial role in the ongoing epidemics of obesity, hypertension, diabetes, and atherosclerotic cardiovascular disease. Until 500 generations ago, all humans consumed only wild and unprocessed food foraged and hunted from their environment. These circumstances provided a diet high in lean protein, polyunsaturated fats (especially omega-3 HDL = high-density lipoprotein; LDL = low-density lipoprotein [ω-3] fatty acids), monounsaturated fats, fiber, vitamins, minerals, antioxidants, and other beneficial phytochemicals. Historical and anthropological studies show huntergatherers generally to be healthy, fit, and largely free of the degenerative cardiovascular diseases common in modern societies. This review outlines the essence of our huntergatherer genetic legacy and suggests practical steps to realign our modern milieu with our ancient genome in an effort to improve cardiovascular health. Mayo Clin Proc. 2004;79:101-108

James H Okeefe - One of the best experts on this subject based on the ideXlab platform.

  • cardiovascular disease resulting from a diet and lifestyle at odds with our paleolithic genome how to become a 21st century hunter gatherer
    Mayo Clinic Proceedings, 2004
    Co-Authors: James H Okeefe, Loren Cordain
    Abstract:

    Our genetic make-up, shaped through millions of years of evolution, determines our nutritional and activity needs. Although the human genome has remained primarily unchanged since the Agricultural Revolution 10,000 years ago, our diet and lifestyle have become progressively more divergent from those of our ancient ancestors. Accumulating evidence suggests that this mismatch between our modern diet and lifestyle and our Paleolithic genome is playing a substantial role in the ongoing epidemics of obesity, hypertension, diabetes, and atherosclerotic cardiovascular disease. Until 500 generations ago, all humans consumed only wild and unprocessed food foraged and hunted from their environment. These circumstances provided a diet high in lean protein, polyunsaturated fats (especially omega-3 [ω-3] fatty acids), monounsaturated fats, fiber, vitamins, minerals, antioxidants, and other beneficial phytochemicals. Historical and anthropological studies show hunter-gatherers generally to be healthy, fit, and largely free of the degenerative cardiovascular diseases common in modern societies. This review outlines the essence of our hunter-gatherer genetic legacy and suggests practical steps to realign our modern milieu with our ancient genome in an effort to improve cardiovascular health.

  • cardiovascular disease resulting from a diet and lifestyle at odds with our paleolithic genome how to become a 21st century hunter gatherer
    Mayo Clinic Proceedings, 2004
    Co-Authors: James H Okeefe, Loren Cordain
    Abstract:

    Our genetic make-up, shaped through millions of years of evolution, determines our nutritional and activity needs. Although the human genome has remained primarily unchanged since the Agricultural Revolution 10,000 years ago, our diet and lifestyle have become progressively more divergent from those of our ancient ancestors. Accumulating evidence suggests that this mismatch between our modern diet and lifestyle and our Paleolithic genome is playing a substantial role in the ongoing epidemics of obesity, hypertension, diabetes, and atherosclerotic cardiovascular disease. Until 500 generations ago, all humans consumed only wild and unprocessed food foraged and hunted from their environment. These circumstances provided a diet high in lean protein, polyunsaturated fats (especially omega-3 HDL = high-density lipoprotein; LDL = low-density lipoprotein [ω-3] fatty acids), monounsaturated fats, fiber, vitamins, minerals, antioxidants, and other beneficial phytochemicals. Historical and anthropological studies show huntergatherers generally to be healthy, fit, and largely free of the degenerative cardiovascular diseases common in modern societies. This review outlines the essence of our huntergatherer genetic legacy and suggests practical steps to realign our modern milieu with our ancient genome in an effort to improve cardiovascular health. Mayo Clin Proc. 2004;79:101-108

Fedacko J. - One of the best experts on this subject based on the ideXlab platform.

  • Nutrition in transition from homo sapiens to homo economicus
    Bentham Science Publishers B.V., 2020
    Co-Authors: Singh R.b., Takahashi T., Nakaoka T., Otsuka K., Toda E., Shi H.h., Lee M.-k., Hristova K., Fedacko J.
    Abstract:

    The food and nutrient intake among Paleolithic Homo sapiens, hunter-gatherers and among Asian and Homo economicus Western populations shows marked variations. Economic development and affluence may be associated with a decrease in the consumption of omega-3 fatty acids, vitamins, antioxidants and amino acids and significant increase in the intakes of carbohydrates, (mainly refined), fat (saturated, trans fat and linoleic acid) and salt compared to the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet Homo sapiens compared to modern Western diet consumed by Homo economicus populations. Approximately 10,000 years ago, prior to the Agricultural Revolution, our diet was based on an enormous variety of wild plants. However, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced by fertilizer based on rapidly grown crops which may result in a decrease in nutrient density and increase in energy. Wheat, corn and rice account for three fourths of the world's grain production on which humans are dependent for their food supply. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. It has been estimated that diet of Homo sapiens was characterized by higher intakes by essential and nonessential amino acids, calcium, potassium, magnesium, flavonoids and w-3 fatty acids whereas modern Western diet of Homo economicus has excess of energy-rich refined carbohydrates, w-6, trans fat and saturated fat and low in protective nutrients. The consumption of such diets in wealthy countries in conjunction with sedentary behavior is associated with increased prevalence of morbidity and mortality due to noncommunicable diseases (NCDs). © Singh et al

  • Nutrition in transition from Homo erectus to Homo modestis
    2020
    Co-Authors: Takahashi T., Singh R.b., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D., Wilson D.w.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © Nova Science Publishers, Inc

  • Nutrition in Transition from Homo erectus to Homo modestis
    Nova Science Publishers Inc., 2020
    Co-Authors: Meester F.d., Singh R.b., Takahashi T., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © 2015 Nova Science Publishers, Inc. All rights reserved

Singh R.b. - One of the best experts on this subject based on the ideXlab platform.

  • Nutrition in transition from homo sapiens to homo economicus
    Bentham Science Publishers B.V., 2020
    Co-Authors: Singh R.b., Takahashi T., Nakaoka T., Otsuka K., Toda E., Shi H.h., Lee M.-k., Hristova K., Fedacko J.
    Abstract:

    The food and nutrient intake among Paleolithic Homo sapiens, hunter-gatherers and among Asian and Homo economicus Western populations shows marked variations. Economic development and affluence may be associated with a decrease in the consumption of omega-3 fatty acids, vitamins, antioxidants and amino acids and significant increase in the intakes of carbohydrates, (mainly refined), fat (saturated, trans fat and linoleic acid) and salt compared to the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet Homo sapiens compared to modern Western diet consumed by Homo economicus populations. Approximately 10,000 years ago, prior to the Agricultural Revolution, our diet was based on an enormous variety of wild plants. However, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced by fertilizer based on rapidly grown crops which may result in a decrease in nutrient density and increase in energy. Wheat, corn and rice account for three fourths of the world's grain production on which humans are dependent for their food supply. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. It has been estimated that diet of Homo sapiens was characterized by higher intakes by essential and nonessential amino acids, calcium, potassium, magnesium, flavonoids and w-3 fatty acids whereas modern Western diet of Homo economicus has excess of energy-rich refined carbohydrates, w-6, trans fat and saturated fat and low in protective nutrients. The consumption of such diets in wealthy countries in conjunction with sedentary behavior is associated with increased prevalence of morbidity and mortality due to noncommunicable diseases (NCDs). © Singh et al

  • Nutrition in transition from Homo erectus to Homo modestis
    2020
    Co-Authors: Takahashi T., Singh R.b., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D., Wilson D.w.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © Nova Science Publishers, Inc

  • Nutrition in Transition from Homo erectus to Homo modestis
    Nova Science Publishers Inc., 2020
    Co-Authors: Meester F.d., Singh R.b., Takahashi T., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © 2015 Nova Science Publishers, Inc. All rights reserved

Takahashi T. - One of the best experts on this subject based on the ideXlab platform.

  • Nutrition in transition from homo sapiens to homo economicus
    Bentham Science Publishers B.V., 2020
    Co-Authors: Singh R.b., Takahashi T., Nakaoka T., Otsuka K., Toda E., Shi H.h., Lee M.-k., Hristova K., Fedacko J.
    Abstract:

    The food and nutrient intake among Paleolithic Homo sapiens, hunter-gatherers and among Asian and Homo economicus Western populations shows marked variations. Economic development and affluence may be associated with a decrease in the consumption of omega-3 fatty acids, vitamins, antioxidants and amino acids and significant increase in the intakes of carbohydrates, (mainly refined), fat (saturated, trans fat and linoleic acid) and salt compared to the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet Homo sapiens compared to modern Western diet consumed by Homo economicus populations. Approximately 10,000 years ago, prior to the Agricultural Revolution, our diet was based on an enormous variety of wild plants. However, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced by fertilizer based on rapidly grown crops which may result in a decrease in nutrient density and increase in energy. Wheat, corn and rice account for three fourths of the world's grain production on which humans are dependent for their food supply. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. It has been estimated that diet of Homo sapiens was characterized by higher intakes by essential and nonessential amino acids, calcium, potassium, magnesium, flavonoids and w-3 fatty acids whereas modern Western diet of Homo economicus has excess of energy-rich refined carbohydrates, w-6, trans fat and saturated fat and low in protective nutrients. The consumption of such diets in wealthy countries in conjunction with sedentary behavior is associated with increased prevalence of morbidity and mortality due to noncommunicable diseases (NCDs). © Singh et al

  • Nutrition in transition from Homo erectus to Homo modestis
    2020
    Co-Authors: Takahashi T., Singh R.b., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D., Wilson D.w.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © Nova Science Publishers, Inc

  • Nutrition in Transition from Homo erectus to Homo modestis
    Nova Science Publishers Inc., 2020
    Co-Authors: Meester F.d., Singh R.b., Takahashi T., Toda E., Lee M.-k., Hristova K., Fedacko J., Shin H.h., Pella D.
    Abstract:

    The food and nutrient intake of Paleolithic hunter-gatherers (Homo erectus) and of Western populations (Homo economicus) show marked variations. With increase in wealth and affluence there is a decrease in the intake of omega-3 fatty acids, vitamins, antioxidants and amino acids and a significant increase in the intake of refined carbohydrates, fats (saturated & trans fats, omega-6 fatty acids) and salt in comparison with those of the Paleolithic period. The protein or amino acid intake was 2.5 fold greater (33 vs. 13%) in the Paleolithic diet of Homo erectus compared to that of the modern Western diet. Prior to the Agricultural Revolution, man's diet was based on an enormous variety of wild plants, eggs, fish and seeds. In comparison, today about 17% of plant species provide 90% of the world's food supply which is mainly contributed by grains produced from fertilizer-based rapidly grown crops potentially lower in nutrient density and higher in energy. Grains are high in omega-6 fatty acids and carbohydrates and low in omega-3 fatty acids and antioxidants compared to leafy green vegetables. The appropriate diet for Homo sapiens is characterized by high levels of protective essential nutrients; amino acids, minerals, vitamins, flavonoids, omega-6/3 fatty acids. Whereas the average diet of Homo erectus did comply with this evolutionary pattern, the modern Western dietary pattern of Homo economicus has excess of energy-rich refined carbohydrates, omega-6, trans and saturated fats. The consumption of such foods in wealthy countries in conjunction with sedentary behavior are associated with increased risk of deaths due to cardiovascular (CVDs) and other non-communicable diseases (NCDs). © 2015 Nova Science Publishers, Inc. All rights reserved