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Albino Rat

The Experts below are selected from a list of 120 Experts worldwide ranked by ideXlab platform

Hala Gabr Metwally – 1st expert on this subject based on the ideXlab platform

  • Effect of Stem Cell Therapy on Induced Diabetic KeRatopathy in Albino Rat
    International journal of stem cells, 2012
    Co-Authors: Maha Baligh Zickri, Nagwa Abdel Wahab Ahmad, Zeinab Mohamad El Maadawi, Yasmin Kamal Mohamady, Hala Gabr Metwally

    Abstract:

    Background and Objectives:
    Type 2 diabetes mellitus (DM) is a prevalent disorder. Diabetic keRatopathy is a well-known ocular complication secondary to type 2 DM. Topical insulin application did not affect apoptosis and necrosis levels in corneal epithelium. Autologous cell transplantation is not a viable option for diabetic patients with bilateral limbal stem cell deficiency. The present study aimed at assessing the possible effect of hemopoeitic stem cell (HSC) therapy on induced diabetic keRatopathy in Albino Rat.

  • effect of stem cell therapy on amiodarone induced fibrosing interstitial lung disease in Albino Rat
    International journal of stem cells, 2011
    Co-Authors: Somaya Saad Zaglool, Maha Baligh Zickri, Dalia Hussein Abd El Aziz, Doaa Mabrouk, Hala Gabr Metwally

    Abstract:

    Background and Objectives:
    The fibrosing forms of interstitial lung disease (ILD) are associated with significant morbidity and mortality. ILD may be idiopathic, secondary to occupational, infection, complicate rheumatic diseases or drug induced. Efficacy of antifibrotic agents is as far as, limited and uncertain. No effective treatment was confirmed for pulmonary fibrosis except lung transplantation. The present study aimed at investigating the possible effect of human cord blood mesenchymal stem cell (MSC) therapy on fibrosing ILD. This was accomplished by using amiodarone as a model of induced lung damage in Albino Rat.

Zhiling Dong – 2nd expert on this subject based on the ideXlab platform

  • impact of acute and chronic stress hormone on male Albino Rat brain
    International Journal of Clinical and Experimental Pathology, 2015
    Co-Authors: Ling Chen, Zhiling Dong

    Abstract:

    The present investigation aimed to evaluate the acute and chronic effect of stress (stress hormone) in male Albino Rat brain. Nor-epinephrine was used for the treatment and saline used for the control. Nor-epinephrine was dissolved in the saline and administered orally to the Rats. Following nor-epinephrine administRation, the brain was removed surgically at 6 h, 12 h and 45 days. Alanine tansaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) were significantly altered in the Rats. Lipid peroxidation was measured as malondialdehyde (MDA), showed altered lipid peroxidation. Hematological markers such as packed cell volume (PCV), white blood cells (WBC), neutrophil, lymphocytes and hemoglobin were significantly altered compared to controls. Altered serum biochemical and hematological markers, lipid peroxidation and enzyme activities leads to adverse effect in the cellular metabolism and physiological activities of Rats.

Maha Baligh Zickri – 3rd expert on this subject based on the ideXlab platform

  • Effect of Stem Cell Therapy on Induced Diabetic KeRatopathy in Albino Rat
    International journal of stem cells, 2012
    Co-Authors: Maha Baligh Zickri, Nagwa Abdel Wahab Ahmad, Zeinab Mohamad El Maadawi, Yasmin Kamal Mohamady, Hala Gabr Metwally

    Abstract:

    Background and Objectives:
    Type 2 diabetes mellitus (DM) is a prevalent disorder. Diabetic keRatopathy is a well-known ocular complication secondary to type 2 DM. Topical insulin application did not affect apoptosis and necrosis levels in corneal epithelium. Autologous cell transplantation is not a viable option for diabetic patients with bilateral limbal stem cell deficiency. The present study aimed at assessing the possible effect of hemopoeitic stem cell (HSC) therapy on induced diabetic keRatopathy in Albino Rat.

  • effect of stem cell therapy on amiodarone induced fibrosing interstitial lung disease in Albino Rat
    International journal of stem cells, 2011
    Co-Authors: Somaya Saad Zaglool, Maha Baligh Zickri, Dalia Hussein Abd El Aziz, Doaa Mabrouk, Hala Gabr Metwally

    Abstract:

    Background and Objectives:
    The fibrosing forms of interstitial lung disease (ILD) are associated with significant morbidity and mortality. ILD may be idiopathic, secondary to occupational, infection, complicate rheumatic diseases or drug induced. Efficacy of antifibrotic agents is as far as, limited and uncertain. No effective treatment was confirmed for pulmonary fibrosis except lung transplantation. The present study aimed at investigating the possible effect of human cord blood mesenchymal stem cell (MSC) therapy on fibrosing ILD. This was accomplished by using amiodarone as a model of induced lung damage in Albino Rat.