The Experts below are selected from a list of 1314 Experts worldwide ranked by ideXlab platform
Gurudutt Tiwari - One of the best experts on this subject based on the ideXlab platform.
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Esophageal Complications Following Aluminium Phosphide Ingestion: An Emerging Issue Among Survivors of Poisoning
Dysphagia, 2010Co-Authors: Rajendra K. Jain, Narendra B. Gouda, Virendra K. Sharma, Tribhuvan N. Dubey, Atul Shende, Rajesh Malik, Gurudutt TiwariAbstract:Aluminium Phosphide ingestion is the most common agricultural poisoning in suburban and rural India and with a high mortality rate. Among survivors of acute poisoning there are recent sporadic reports of esophageal complications such as esophageal strictures and tracheo-esophageal fistula. The present study was carried out to determine the incidence, natural history, and treatment outcome of local esophageal complications in survivors of Aluminium Phosphide poisoning with complaints of dysphagia. All confirmed cases of poisoning with Aluminium Phosphide ingestion were admitted in Hamidia Hospital, Gandhi Medical College, Bhopal, Madhya Pradesh, India, from October 2007 to October 2008. Survivors with complaints of dysphagia underwent a barium study and upper gastrointestinal endoscopy to determine site and nature of esophageal complications. All cases of strictures were treated with fluoroscopy-guided Savary–Gilliard bougie dilation, and patients with tracheo-esophageal fistula underwent surgery. Of 104 confirmed cases, 31 survived. Ten survivors with dysphagia were found to have single short-segment esophageal stricture and two patients with odynophagia and swallow–cough sequence had tracheo-esophageal fistula. All cases of esophageal strictures responded successfully to Savary–Gilliard dilation in six to ten sessions without any major complications. Patients with tracheo-esophageal fistula were treated successfully via surgery. Nearly one-third of survivors of Aluminium Phosphide ingestion developed esophageal complications. Hence, we conclude that all survivors of Aluminium Phosphide poisoning must undergo barium swallow and endoscopic examination for early detection of esophageal complications. Prevention of esophageal complications after Aluminium Phosphide ingestion needs to be given adequate attention because tracheo-esophageal fistula and esophageal stricture are associated with high morbidity. When one finds esophageal stricture or fistula, the possibility of Aluminium Phosphide ingestion should always be considered.
Banwari L. Meel - One of the best experts on this subject based on the ideXlab platform.
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Aluminium Phosphide (tank pill) poisoning in the Transkei region of South Africa: a case report
2016Co-Authors: Banwari L. Meel, Md MphilAbstract:About half a million people die each year as a result of various kinds of poisoning. The incidence of pesticide poisoning, which is high in developing countries, has doubled over the past 10 years. Aluminium Phosphide is a deadly fumigant pesticide. A 21-year-old man committed suicide by ingesting Aluminium Phosphide, which he had available in his home. He had been charged with rape, and was to appear in court. Soon after ingestion, he told his grandmother about the suicide attempt. He was taken to a nearby hospital, where he was dead within an hour of arriving. The mechanism of action, symptoms and signs will be discussed in this report. The purpose of this case report is to highlight the problem of Aluminium Phosphide poisoning in the Transkei region of South Africa. Med Sci Law 2011; 51: 116–118. DOI: 10.1258/msl.2010.01020
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Aluminium Phosphide (tank pill) poisoning in the Transkei region of South Africa: a case report
Medicine Science and the Law, 2011Co-Authors: Banwari L. MeelAbstract:About half a million people die each year as a result of various kinds of poisoning. The incidence of pesticide poisoning, which is high in developing countries, has doubled over the past 10 years. Aluminium Phosphide is a deadly fumigant pesticide. A 21-year-old man committed suicide by ingesting Aluminium Phosphide, which he had available in his home. He had been charged with rape, and was to appear in court. Soon after ingestion, he told his grandmother about the suicide attempt. He was taken to a nearby hospital, where he was dead within an hour of arriving. The mechanism of action, symptoms and signs will be discussed in this report. The purpose of this case report is to highlight the problem of Aluminium Phosphide poisoning in the Transkei region of South Africa. Language: en
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Aluminium Phosphide tank pill poisoning in the transkei region of south africa a case report
Medicine Science and The Law, 2011Co-Authors: Banwari L. MeelAbstract:About half a million people die each year as a result of various kinds of poisoning. The incidence of pesticide poisoning, which is high in developing countries, has doubled over the past 10 years. Aluminium Phosphide is a deadly fumigant pesticide. A 21-year-old man committed suicide by ingesting Aluminium Phosphide, which he had available in his home. He had been charged with rape, and was to appear in court. Soon after ingestion, he told his grandmother about the suicide attempt. He was taken to a nearby hospital, where he was dead within an hour of arriving. The mechanism of action, symptoms and signs will be discussed in this report. The purpose of this case report is to highlight the problem of Aluminium Phosphide poisoning in the Transkei region of South Africa.
Sanjay Kumar Somani - One of the best experts on this subject based on the ideXlab platform.
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Aluminium Phosphide-Induced Esophageal Stricture Palliation with Polyflex Stent
Dysphagia, 2008Co-Authors: Sanjay Kumar SomaniAbstract:A 21-year-old woman developed midesophageal stricture two weeks after ingestion of Aluminium Phosphide (AlP) tablets. Aluminium Phosphide is a lethal protoplasmic toxin and is also the most common cause of suicidal poisoning in northern India. Upper gastrointestinal endoscopy (UGIE) showed a tight esophageal stricture 29 cm from the incisors with a circumferential ulcer. Dilatation up to 17 mm was done using Savary-Gilliard dilators. She had repeated dilatations three times at nearly two-week intervals. In view of the resistant stricture, a silicone Polyflex stent was placed across the stricture and removed after 3 months; there was no recurrence of stricture even after three months of follow-up. Patients with recurrent esophageal stricture and those with fistula may benefit from silicone expandable stents.
Samah F Ibrahim - One of the best experts on this subject based on the ideXlab platform.
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moringa oleifera extract lam attenuates Aluminium Phosphide induced acute cardiac toxicity in rats
Toxicology reports, 2018Co-Authors: Ahmed S Gouda, Nagla A Elnabarawy, Samah F IbrahimAbstract:Abstract Background Moringa oleifera extract (Lam) has many antioxidant and protective properties. Objective: to investigate the antioxidant activities of Lam in counteracting the high oxidative stress caused by acute sub-lethal Aluminium Phosphide (AlP) intoxication in rat heart. These activities will be detected by histopathological examination and some oxidative stress biomarkers. Methods a single sub-lethal dose of Alp (2 mg/kg body weight) was administered orally, and Lam was given orally at a dose (100 mg/kg body weight) one hour after receiving AlP to rats. Results Aluminium Phosphide caused significant cardiac histopathological changes with a significant increase in malondialdehyde (MDA); lipid peroxidation marker; and a significant depletion of antioxidant enzymes (catalase and glutathione reductase). However, treatment with Lam protected efficiently the cardiac tissue of intoxicated rats by increasing antioxidants levels with slight decreasing in MDA production compared to untreated group. Conclusions This study suggested that Moringa oleifera extract could possibly restore the altered cardiac histopathology and some antioxidant power in AlP intoxicated rats, and it could even be used as adjuvant therapy against AlP-induced cardiotoxicity.
Rajendra K. Jain - One of the best experts on this subject based on the ideXlab platform.
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Esophageal Complications Following Aluminium Phosphide Ingestion: An Emerging Issue Among Survivors of Poisoning
Dysphagia, 2010Co-Authors: Rajendra K. Jain, Narendra B. Gouda, Virendra K. Sharma, Tribhuvan N. Dubey, Atul Shende, Rajesh Malik, Gurudutt TiwariAbstract:Aluminium Phosphide ingestion is the most common agricultural poisoning in suburban and rural India and with a high mortality rate. Among survivors of acute poisoning there are recent sporadic reports of esophageal complications such as esophageal strictures and tracheo-esophageal fistula. The present study was carried out to determine the incidence, natural history, and treatment outcome of local esophageal complications in survivors of Aluminium Phosphide poisoning with complaints of dysphagia. All confirmed cases of poisoning with Aluminium Phosphide ingestion were admitted in Hamidia Hospital, Gandhi Medical College, Bhopal, Madhya Pradesh, India, from October 2007 to October 2008. Survivors with complaints of dysphagia underwent a barium study and upper gastrointestinal endoscopy to determine site and nature of esophageal complications. All cases of strictures were treated with fluoroscopy-guided Savary–Gilliard bougie dilation, and patients with tracheo-esophageal fistula underwent surgery. Of 104 confirmed cases, 31 survived. Ten survivors with dysphagia were found to have single short-segment esophageal stricture and two patients with odynophagia and swallow–cough sequence had tracheo-esophageal fistula. All cases of esophageal strictures responded successfully to Savary–Gilliard dilation in six to ten sessions without any major complications. Patients with tracheo-esophageal fistula were treated successfully via surgery. Nearly one-third of survivors of Aluminium Phosphide ingestion developed esophageal complications. Hence, we conclude that all survivors of Aluminium Phosphide poisoning must undergo barium swallow and endoscopic examination for early detection of esophageal complications. Prevention of esophageal complications after Aluminium Phosphide ingestion needs to be given adequate attention because tracheo-esophageal fistula and esophageal stricture are associated with high morbidity. When one finds esophageal stricture or fistula, the possibility of Aluminium Phosphide ingestion should always be considered.
