Ameloblastic Fibroma - Explore the Science & Experts | ideXlab

Scan Science and Technology

Contact Leading Edge Experts & Companies

Ameloblastic Fibroma

The Experts below are selected from a list of 1197 Experts worldwide ranked by ideXlab platform

Ameloblastic Fibroma – Free Register to Access Experts & Abstracts

Akiyoshi Hirano – One of the best experts on this subject based on the ideXlab platform.

  • malignant transformation of Ameloblastic Fibroma to Ameloblastic fibrosarcoma case report and review of the literature
    Journal of Cranio-maxillofacial Surgery, 2005
    Co-Authors: Kazuo Kobayashi, Ryuichi Murakami, Tohru Fujii, Akiyoshi Hirano
    Abstract:

    Summary Introduction Ameloblastic fibrosarcoma is a rare malignant odontogenic tumour and is regarded as the malignant counterpart of the Ameloblastic Fibroma. The epithelial component remains benign, but the mesenchymal component becomes malignant. The diagnosis is made by histopathology. Patient The case of a 26-year-old man who underwent curettage of an Ameloblastic Fibroma and died of an Ameloblastic fibrosarcoma is presented, and the course of malignant transformation is analysed retrospectively. Conclusion One-third of Ameloblastic fibrosarcoma cases seem to have developed from recurrent Ameloblastic Fibromas. Knowledge of the malignant potential in the mesenchymal spindle cells of Ameloblastic Fibroma will assist in determining the management of these benign tumours, and may prevent malignant transformation to Ameloblastic fibrosarcoma.

Riya Kuklani – One of the best experts on this subject based on the ideXlab platform.

  • Ameloblastic Fibroma: A Rare Entity of the Mandible
    American Journal of Clinical Pathology, 2019
    Co-Authors: Sakshi Sakshi, Riya Kuklani
    Abstract:

    Abstract Ameloblastic Fibroma (AF) is an uncommon benign odontogenic true mixed tumor comprising neoplastic epithelial and mesenchymal tissues. It constitutes only approximately 2% of odontogenic tumors and is defined by the World Health Organization (WHO) as “neoplasm composed of proliferating odontogenic epithelium embedded in cellular ectomesenchymal tissue that resembles the dental papilla and epithelial strands and varying degrees of inductive changes and dental hard tissue formation.” The tumor is most common in the first and second decades of life with a slight male predilection. The most common site is the posterior mandible and 75% of the cases are associated with an unerupted tooth. Radiologically, it may present as a unilocular or multilocular lesion. The treatment of choice could range from aggressive curettage for a small unilocular lesion to wide local excision for a large multilocular lesion. The prognosis is usually good, with a recurrence rate of approximately 20%. Here we present a case of a 13-year-old male with a multilocular expansile cystic lesion associated with nonvital tooth 20 and tooth 21 since 2016. An incisional biopsy was performed and the microscopic examination revealed small masses of cellular fibrous and myxoid connective tissue containing long narrow cords of odontogenic epithelium. The odontogenic islands were basophilic with peripheral nuclear palisading of the basal cell layer, consistent with an Ameloblastic Fibroma. Complete curettage was performed and the patient is being followed up with no recurrence since 2 months. We reviewed the literature with regard to clinical, histopathological, and radiological findings and reached the conclusion that malignant transformation of Ameloblastic Fibroma into Ameloblastic fibrosarcoma is uncommon but well documented. AF needs to be distinguished from ameloblastoma and Ameloblastic fibrosarcoma, since these two tumors can be locally invasive and have greater potential for recurrence than Ameloblastic Fibroma.

Kazuo Kobayashi – One of the best experts on this subject based on the ideXlab platform.

  • malignant transformation of Ameloblastic Fibroma to Ameloblastic fibrosarcoma case report and review of the literature
    Journal of Cranio-maxillofacial Surgery, 2005
    Co-Authors: Kazuo Kobayashi, Ryuichi Murakami, Tohru Fujii, Akiyoshi Hirano
    Abstract:

    Summary Introduction Ameloblastic fibrosarcoma is a rare malignant odontogenic tumour and is regarded as the malignant counterpart of the Ameloblastic Fibroma. The epithelial component remains benign, but the mesenchymal component becomes malignant. The diagnosis is made by histopathology. Patient The case of a 26-year-old man who underwent curettage of an Ameloblastic Fibroma and died of an Ameloblastic fibrosarcoma is presented, and the course of malignant transformation is analysed retrospectively. Conclusion One-third of Ameloblastic fibrosarcoma cases seem to have developed from recurrent Ameloblastic Fibromas. Knowledge of the malignant potential in the mesenchymal spindle cells of Ameloblastic Fibroma will assist in determining the management of these benign tumours, and may prevent malignant transformation to Ameloblastic fibrosarcoma.