The Experts below are selected from a list of 1854 Experts worldwide ranked by ideXlab platform
Michael C. Willis - One of the best experts on this subject based on the ideXlab platform.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron-asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:Abstract The combination of Mg(ClO 4 ) 2 , 2,2′-bipyridine and N -methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N -Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α- iso -propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti -configured Mannich products dominate.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron: Asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:The combination of Mg(ClO4)2, 2,2′-bipyridine and N-methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N-Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α-iso-propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti-configured Mannich products dominate. © 2009 Elsevier Ltd. All rights reserved
Nikki E. Stainforth - One of the best experts on this subject based on the ideXlab platform.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected alpha-hydroxy-beta-Aminoketones
'Elsevier BV', 2009Co-Authors: Nikki E. Stainforth, Ga Cutting, Mp John, Mc WillisAbstract:The combination of Mg(ClO4)2, 2,2′-bipyridine and N-methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N-Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α-iso-propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti-configured Mannich products dominate. © 2009 Elsevier Ltd. All rights reserved
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron-asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:Abstract The combination of Mg(ClO 4 ) 2 , 2,2′-bipyridine and N -methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N -Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α- iso -propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti -configured Mannich products dominate.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron: Asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:The combination of Mg(ClO4)2, 2,2′-bipyridine and N-methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N-Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α-iso-propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti-configured Mannich products dominate. © 2009 Elsevier Ltd. All rights reserved
Adinath Majee - One of the best experts on this subject based on the ideXlab platform.
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Self-Catalyzed Rapid Synthesis of N-Acylated/N-Formylated α-Aminoketones and N-Hydroxymethylated Formamides from 3-Aryl-2H-Azirines and 2-Me/Ph-3-Aryl-2H-Azirines
Organic letters, 2020Co-Authors: Sougata Santra, Grigory V. Zyryanov, Adinath MajeeAbstract:A rapid and effective method has been established for the synthesis of N-acylated α-Aminoketone derivatives by the reaction of 3-aryl-2H-azirines and highly substituted 2-Me/Ph-3-aryl-2H-azirines w...
Sougata Santra - One of the best experts on this subject based on the ideXlab platform.
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Self-Catalyzed Rapid Synthesis of N-Acylated/N-Formylated α-Aminoketones and N-Hydroxymethylated Formamides from 3-Aryl-2H-Azirines and 2-Me/Ph-3-Aryl-2H-Azirines
Organic letters, 2020Co-Authors: Sougata Santra, Grigory V. Zyryanov, Adinath MajeeAbstract:A rapid and effective method has been established for the synthesis of N-acylated α-Aminoketone derivatives by the reaction of 3-aryl-2H-azirines and highly substituted 2-Me/Ph-3-aryl-2H-azirines w...
Matthew P. John - One of the best experts on this subject based on the ideXlab platform.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron-asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:Abstract The combination of Mg(ClO 4 ) 2 , 2,2′-bipyridine and N -methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N -Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α- iso -propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti -configured Mannich products dominate.
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Direct catalytic diastereoselective Mannich reactions: the synthesis of protected α-hydroxy-β-Aminoketones
Tetrahedron: Asymmetry, 2009Co-Authors: Nikki E. Stainforth, Gary A. Cutting, Matthew P. John, Michael C. WillisAbstract:The combination of Mg(ClO4)2, 2,2′-bipyridine and N-methylmorpholine generates an effective catalyst system for the direct addition of α-carbonate-substituted ketones to aryl N-Ts imines. Methyl-carbonate-substituted ketones deliver acyclic α-hydroxy-β-Aminoketone derivates, while ketones substituted with α-iso-propenyl-carbonates furnish cyclic carbamate adducts. In both cases the anti-configured Mannich products dominate. © 2009 Elsevier Ltd. All rights reserved