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D I Xueqin – One of the best experts on this subject based on the ideXlab platform.
clinical investigation of heparin for prevention children s renal damage caused by Anaphylactoid PurpuraJournal of Hainan Medical University, 2011Co-Authors: D I XueqinAbstract:
Objective: To investigate the clinical effects of heparin for prevention of children′s renal damage caused by allergic Purpura.Methods: Sixty-eight children with allergic Purpura were randomly divided into treatment group and control group with 34 cases in each group.Both groups were treated with routine therapy,while the treatment group was also given injection of heparin at 100 u/Kg·d once per day for 2 consecutive weeks.Renal damage caused by Anaphylactoid Purpura was observed.Results: According to 3-month follow up,2(5.9%) and 7(20.6%) cases of nephritis caused by Anaphylactoid Purpura was observed in the treatment and control group,respectively,showing significant difference between the two groups(χ2=6.635,P0.05).Whereas,there were no significant differences between two groups in the degree of renal damage(χ2=4.605,P0.05).Conclusions: Heparin can effectively reduce the incidence of renal damage among children with allergic Purpura,indicating its renal protection.
Fang Bao-xi – One of the best experts on this subject based on the ideXlab platform.
A meta-analysis on curative effect of montelukast sodium in the treatment of Anaphylactoid Purpura in childrenOccupation and Health, 2013Co-Authors: Fang Bao-xiAbstract:
[Objective]To evaluate the efficacy and safety of montelukast sodium in the treatment of Anaphylactoid Purpura in children.[Methods]The clinical trials of montelukast sodium for Anaphylactoid Purpura in children were collected by retrieving domestic and foreign medical databases.The meta-analysis was performed by RevMan 5.0 software.[Results]11 clinical trials were searched,and a total of 882 patients were involved.The meta-analysis showed that the montelukast sodium had better curative effect for Anaphylactoid Purpura in children as compared with the conventional therapy.RR(95% CI) of the obvious effective rate and effective rate was 1.38(1.20-1.59) and 1.21(1.13-1.28) respectively.[Conclusion]According to the available data,montelukast sodium has definite clinical effect in the treatment of Anaphylactoid Purpura in children.However,due to poor quality and small sample size of included studies,it is necessary to carry out more high-quality clinical trials to verify this result.
Jin Shun – One of the best experts on this subject based on the ideXlab platform.
Determination of serum specific IgE measurement in Anaphylactoid PurpuraJournal of Medical Science Yanbian University, 2004Co-Authors: Jin ShunAbstract:
OBJECTIVE?To analyse the significance of diagnosing the pathogenies for the serum specific IgE level in the Anaphylactoid Purpura patients.?METHODS?Using the IgE allergen external assay(702), the specific IgE level was detected in the serum of 92 cases of Anaphylactoid Purpura.?RESULTS?Total positive rate of serum IgE in the ingestive group was 94%, total positive rate of allergen’s IgE was 68%, in witch 20 cases(22%) were sensitive to over 2 kinds of ingestants and 8 cases(9%) over 3 kinds of ingestants. The common foods for inducing allergy were milk, fish, cab, shrimps, soybeans, peanuts, egg white and yolk, pork, beef and mutton in turn.?CONCLUSION?The serum specific IgE level has important reference significance for diagnosing the pathogenies in the Anaphylactoid Purpura.