Animal Diarrhea - Explore the Science & Experts | ideXlab

Scan Science and Technology

Contact Leading Edge Experts & Companies

Animal Diarrhea

The Experts below are selected from a list of 9939 Experts worldwide ranked by ideXlab platform

Animal Diarrhea – Free Register to Access Experts & Abstracts

Joseph L Derisi – One of the best experts on this subject based on the ideXlab platform.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Thomas D. Haggerty, Julie Parsonnet, Don Ganem, Joseph L Derisi

    Abstract:

    Background
    Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Julie Parsonnet, Don Ganem, Thomas Haggerty, Joseph L Derisi

    Abstract:

    Background Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease. Results A pool of 141 pediatric gastroenteritis samples that were previously found to be negative for known Diarrheal viruses was subjected to pyrosequencing. From a total of 937,935 sequence reads, a collection of 849 reads distantly related to Aichi virus were assembled and found to comprise 75% of a novel picornavirus genome. The complete genome was subsequently cloned and found to share 52.3% nucleotide pairwise identity and 38.9% amino acid identity to Aichi virus. The low level of sequence identity suggests a novel picornavirus genus which we have designated klassevirus. Blinded screening of 751 stool specimens from both symptomatic and asymptomatic individuals revealed a second positive case of klassevirus infection, which was subsequently found to be from the index case’s 11-month old twin. Conclusion We report the discovery of human klassevirus 1, a member of a novel picornavirus genus, in stool from two infants from Northern California. Further characterization and epidemiological studies will be required to establish whether klasseviruses are significant causes of human infection.

Alexander L. Greninger – One of the best experts on this subject based on the ideXlab platform.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Thomas D. Haggerty, Julie Parsonnet, Don Ganem, Joseph L Derisi

    Abstract:

    Background
    Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Julie Parsonnet, Don Ganem, Thomas Haggerty, Joseph L Derisi

    Abstract:

    Background Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease. Results A pool of 141 pediatric gastroenteritis samples that were previously found to be negative for known Diarrheal viruses was subjected to pyrosequencing. From a total of 937,935 sequence reads, a collection of 849 reads distantly related to Aichi virus were assembled and found to comprise 75% of a novel picornavirus genome. The complete genome was subsequently cloned and found to share 52.3% nucleotide pairwise identity and 38.9% amino acid identity to Aichi virus. The low level of sequence identity suggests a novel picornavirus genus which we have designated klassevirus. Blinded screening of 751 stool specimens from both symptomatic and asymptomatic individuals revealed a second positive case of klassevirus infection, which was subsequently found to be from the index case’s 11-month old twin. Conclusion We report the discovery of human klassevirus 1, a member of a novel picornavirus genus, in stool from two infants from Northern California. Further characterization and epidemiological studies will be required to establish whether klasseviruses are significant causes of human infection.

Charles Y Chiu – One of the best experts on this subject based on the ideXlab platform.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Thomas D. Haggerty, Julie Parsonnet, Don Ganem, Joseph L Derisi

    Abstract:

    Background
    Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease.

  • The complete genome of klassevirus – a novel picornavirus in pediatric stool
    Virology Journal, 2009
    Co-Authors: Alexander L. Greninger, Charles Runckel, Charles Y Chiu, Julie Parsonnet, Don Ganem, Thomas Haggerty, Joseph L Derisi

    Abstract:

    Background Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and Animal Diarrhea. Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease. Results A pool of 141 pediatric gastroenteritis samples that were previously found to be negative for known Diarrheal viruses was subjected to pyrosequencing. From a total of 937,935 sequence reads, a collection of 849 reads distantly related to Aichi virus were assembled and found to comprise 75% of a novel picornavirus genome. The complete genome was subsequently cloned and found to share 52.3% nucleotide pairwise identity and 38.9% amino acid identity to Aichi virus. The low level of sequence identity suggests a novel picornavirus genus which we have designated klassevirus. Blinded screening of 751 stool specimens from both symptomatic and asymptomatic individuals revealed a second positive case of klassevirus infection, which was subsequently found to be from the index case’s 11-month old twin. Conclusion We report the discovery of human klassevirus 1, a member of a novel picornavirus genus, in stool from two infants from Northern California. Further characterization and epidemiological studies will be required to establish whether klasseviruses are significant causes of human infection.