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Hongliang Zheng – One of the best experts on this subject based on the ideXlab platform.

  • Immediate Ansa Cervicalis-to-Recurrent Laryngeal Nerve Anastomosis for the Management of Recurrent Laryngeal Nerve Infiltration by a Differentiated Thyroid Carcinoma.
    ORL, 2020
    Co-Authors: Wei Wang, Yingna Gao, Shicai Chen, Fei Liu, Caiyun Zhang, Mengjie Chen, Hongliang Zheng

    Abstract:

    OBJECTIVES The optimal surgical approach to treat recurrent laryngeal nerve (RLN) infiltration by differentiated thyroid cancer (DTC) remains a subject of debate. This study explored the feasibility and efficiency of immediate Ansa Cervicalis nerve (ACN)-to-RLN anastomosis for the management of RLN infiltration by DTC. MATERIAL AND METHODS Fifty-three patients who underwent immediate ACN-to-RLN anastomosis during DTC extirpation were enrolled in the present study. Thirty-seven cases presented with unilateral vocal cord paralysis before the operation (Group A), and another 16 patients presented with normal vocal cord mobility preoperatively (Group B). Multidimensional assessments, videostroboscopy, voice assessment, and laryngeal electromyography (LEMG) were performed preoperatively and postoperatively. RESULTS All videostroboscopy, voice assessment and LEMG parameters in Group A deteriorated 1 month after the operation and improved 1 year after the operation compared with preoperative data. In Group B, all parameters 1 year after the operation improved significantly compared with the corresponding parameters 1 month after the operation. LEMG in Group A and B provided substantial evidence for the maturation of neural regeneration from ACN and demonstrated that the laryngeal muscles were reinnervated successfully by this procedure. CONCLUSIONS If the RLN is infiltrated by DTC, immediate ACN-to-RLN anastomosis during complete excision of DTC could restore satisfactory phonatory function and does not compromise oncological radicality.

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  • the efficacy of Ansa Cervicalis anterior root for unilateral recurrent laryngeal nerve injury
    Chinese journal of otorhinolaryngology head and neck surgery, 2018
    Co-Authors: Yingna Gao, Shicai Chen, Donghui Chen, Wei Wang, Fei Liu, Minhui Zhu, Hongliang Zheng

    Abstract:

    Objective
    To discuss the long-term efficacy of laryngeal reinnervation using the anterior root of the Ansa Cervicalis in the treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery.

    Method
    From January 2010 to January 2016, a total of 39 UVFP patients who underwent Ansa Cervicalis anterior root-to-recurrent laryngeal nerve (RLN) anastomosis and who had suffered nerve disfunction for 6 to 24 months were enrolled as UVFP group.Another 39 age and gender matched normal subjects served as control group. Videostroboscopy, vocal function assessment (acoustic analysis, perceptual evaluation and maximum phonation time), and laryngeal electromyography were performed preoperatively and postoperatively for assessing surgery efficacy. Paired sample t test was used for statistical analysis.

    Result
    Videostroboscopic reports indicated that the glottic closure, vocal fold edge, vocal fold position, phase symmetry and regularity were significantly improved in the UVFP group (P 0.05, respectively). Both the postoperative GRBAS assessment and acoustic parameters were also significantly improved in the UVFP group, Pre-operative acoustic parameters/Post-operative acoustic parameters were 1.68±0.82/0.39±0.27, 10.08±2.56/4.58±2.96, 0.203±0.216/0.018±0.038, 5.96±1.92/17.42±4.11(P 0.05, respectively).

    Conclusion
    Delayed laryngeal reinnervation with the anterior root of Ansa Cervicalis, it can restore the physiological laryngeal phonatory function to the normal or a nearly normal voice quality, which is a feasible and effective approach for the treatment of thyroid surgery-related UVFP.

    Key words:
    Recurrent laryngeal nerve; Vocal cord paralysis; Ansa Cervicalis ventral root; Nerve repair

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  • Bridging gaps between the recurrent laryngeal nerve and Ansa Cervicalis using autologous nerve grafts.
    Journal of Voice, 2013
    Co-Authors: Fei Liu, Donghui Chen, Shicai Chen, Song Shi, Hongliang Zheng

    Abstract:

    Summary Objectives/Hypothesis We investigated the clinical efficacy of free nerve grafts in bridging gaps between the recurrent laryngeal nerve (RLN) and Ansa Cervicalis in patients with unilateral RLN injury. Study Design We retrospectively reviewed the charts of 14 patients who underwent relevant free nerve grafting and assessed the clinical outcomes of this procedure. Methods Between January 2000 and January 2010, 14 patients with unilateral vocal fold paralysis were enrolled in this study. In all patients, the RLN was resected and free nerve grafts were applied to bridge the gap between the distal stump of the RLN and the anterior root of Ansa Cervicalis during surgery. Videostroboscopy, acoustic analysis, perceptual evaluation, maximum phonation time (MPT), and laryngeal electromyography (EMG) were performed both preoperatively and postoperatively to assess the clinical outcomes. Results Videostroboscopic findings showed that glottic closure, vocal fold edge, vocal fold position, phase symmetry, and phase regularity were significantly improved postoperatively ( P P P P Conclusions Free nerve grafting is an effective procedure in bridging the gap between the RLN and Ansa Cervicalis in patients with unilateral RLN injury, as well as a safe procedure without obvious morbidity. A satisfactory vocal outcome can be obtained.

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Shicai Chen – One of the best experts on this subject based on the ideXlab platform.

  • Immediate Ansa Cervicalis-to-Recurrent Laryngeal Nerve Anastomosis for the Management of Recurrent Laryngeal Nerve Infiltration by a Differentiated Thyroid Carcinoma.
    ORL, 2020
    Co-Authors: Wei Wang, Yingna Gao, Shicai Chen, Fei Liu, Caiyun Zhang, Mengjie Chen, Hongliang Zheng

    Abstract:

    OBJECTIVES The optimal surgical approach to treat recurrent laryngeal nerve (RLN) infiltration by differentiated thyroid cancer (DTC) remains a subject of debate. This study explored the feasibility and efficiency of immediate Ansa Cervicalis nerve (ACN)-to-RLN anastomosis for the management of RLN infiltration by DTC. MATERIAL AND METHODS Fifty-three patients who underwent immediate ACN-to-RLN anastomosis during DTC extirpation were enrolled in the present study. Thirty-seven cases presented with unilateral vocal cord paralysis before the operation (Group A), and another 16 patients presented with normal vocal cord mobility preoperatively (Group B). Multidimensional assessments, videostroboscopy, voice assessment, and laryngeal electromyography (LEMG) were performed preoperatively and postoperatively. RESULTS All videostroboscopy, voice assessment and LEMG parameters in Group A deteriorated 1 month after the operation and improved 1 year after the operation compared with preoperative data. In Group B, all parameters 1 year after the operation improved significantly compared with the corresponding parameters 1 month after the operation. LEMG in Group A and B provided substantial evidence for the maturation of neural regeneration from ACN and demonstrated that the laryngeal muscles were reinnervated successfully by this procedure. CONCLUSIONS If the RLN is infiltrated by DTC, immediate ACN-to-RLN anastomosis during complete excision of DTC could restore satisfactory phonatory function and does not compromise oncological radicality.

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  • the efficacy of Ansa Cervicalis anterior root for unilateral recurrent laryngeal nerve injury
    Chinese journal of otorhinolaryngology head and neck surgery, 2018
    Co-Authors: Yingna Gao, Shicai Chen, Donghui Chen, Wei Wang, Fei Liu, Minhui Zhu, Hongliang Zheng

    Abstract:

    Objective
    To discuss the long-term efficacy of laryngeal reinnervation using the anterior root of the Ansa Cervicalis in the treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery.

    Method
    From January 2010 to January 2016, a total of 39 UVFP patients who underwent Ansa Cervicalis anterior root-to-recurrent laryngeal nerve (RLN) anastomosis and who had suffered nerve disfunction for 6 to 24 months were enrolled as UVFP group.Another 39 age and gender matched normal subjects served as control group. Videostroboscopy, vocal function assessment (acoustic analysis, perceptual evaluation and maximum phonation time), and laryngeal electromyography were performed preoperatively and postoperatively for assessing surgery efficacy. Paired sample t test was used for statistical analysis.

    Result
    Videostroboscopic reports indicated that the glottic closure, vocal fold edge, vocal fold position, phase symmetry and regularity were significantly improved in the UVFP group (P 0.05, respectively). Both the postoperative GRBAS assessment and acoustic parameters were also significantly improved in the UVFP group, Pre-operative acoustic parameters/Post-operative acoustic parameters were 1.68±0.82/0.39±0.27, 10.08±2.56/4.58±2.96, 0.203±0.216/0.018±0.038, 5.96±1.92/17.42±4.11(P 0.05, respectively).

    Conclusion
    Delayed laryngeal reinnervation with the anterior root of Ansa Cervicalis, it can restore the physiological laryngeal phonatory function to the normal or a nearly normal voice quality, which is a feasible and effective approach for the treatment of thyroid surgery-related UVFP.

    Key words:
    Recurrent laryngeal nerve; Vocal cord paralysis; Ansa Cervicalis ventral root; Nerve repair

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  • Bridging gaps between the recurrent laryngeal nerve and Ansa Cervicalis using autologous nerve grafts.
    Journal of Voice, 2013
    Co-Authors: Fei Liu, Donghui Chen, Shicai Chen, Song Shi, Hongliang Zheng

    Abstract:

    Summary Objectives/Hypothesis We investigated the clinical efficacy of free nerve grafts in bridging gaps between the recurrent laryngeal nerve (RLN) and Ansa Cervicalis in patients with unilateral RLN injury. Study Design We retrospectively reviewed the charts of 14 patients who underwent relevant free nerve grafting and assessed the clinical outcomes of this procedure. Methods Between January 2000 and January 2010, 14 patients with unilateral vocal fold paralysis were enrolled in this study. In all patients, the RLN was resected and free nerve grafts were applied to bridge the gap between the distal stump of the RLN and the anterior root of Ansa Cervicalis during surgery. Videostroboscopy, acoustic analysis, perceptual evaluation, maximum phonation time (MPT), and laryngeal electromyography (EMG) were performed both preoperatively and postoperatively to assess the clinical outcomes. Results Videostroboscopic findings showed that glottic closure, vocal fold edge, vocal fold position, phase symmetry, and phase regularity were significantly improved postoperatively ( P P P P Conclusions Free nerve grafting is an effective procedure in bridging the gap between the RLN and Ansa Cervicalis in patients with unilateral RLN injury, as well as a safe procedure without obvious morbidity. A satisfactory vocal outcome can be obtained.

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Wei Wang – One of the best experts on this subject based on the ideXlab platform.

  • Immediate Ansa Cervicalis-to-Recurrent Laryngeal Nerve Anastomosis for the Management of Recurrent Laryngeal Nerve Infiltration by a Differentiated Thyroid Carcinoma.
    ORL, 2020
    Co-Authors: Wei Wang, Yingna Gao, Shicai Chen, Fei Liu, Caiyun Zhang, Mengjie Chen, Hongliang Zheng

    Abstract:

    OBJECTIVES The optimal surgical approach to treat recurrent laryngeal nerve (RLN) infiltration by differentiated thyroid cancer (DTC) remains a subject of debate. This study explored the feasibility and efficiency of immediate Ansa Cervicalis nerve (ACN)-to-RLN anastomosis for the management of RLN infiltration by DTC. MATERIAL AND METHODS Fifty-three patients who underwent immediate ACN-to-RLN anastomosis during DTC extirpation were enrolled in the present study. Thirty-seven cases presented with unilateral vocal cord paralysis before the operation (Group A), and another 16 patients presented with normal vocal cord mobility preoperatively (Group B). Multidimensional assessments, videostroboscopy, voice assessment, and laryngeal electromyography (LEMG) were performed preoperatively and postoperatively. RESULTS All videostroboscopy, voice assessment and LEMG parameters in Group A deteriorated 1 month after the operation and improved 1 year after the operation compared with preoperative data. In Group B, all parameters 1 year after the operation improved significantly compared with the corresponding parameters 1 month after the operation. LEMG in Group A and B provided substantial evidence for the maturation of neural regeneration from ACN and demonstrated that the laryngeal muscles were reinnervated successfully by this procedure. CONCLUSIONS If the RLN is infiltrated by DTC, immediate ACN-to-RLN anastomosis during complete excision of DTC could restore satisfactory phonatory function and does not compromise oncological radicality.

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  • the efficacy of Ansa Cervicalis anterior root for unilateral recurrent laryngeal nerve injury
    Chinese journal of otorhinolaryngology head and neck surgery, 2018
    Co-Authors: Yingna Gao, Shicai Chen, Donghui Chen, Wei Wang, Fei Liu, Minhui Zhu, Hongliang Zheng

    Abstract:

    Objective
    To discuss the long-term efficacy of laryngeal reinnervation using the anterior root of the Ansa Cervicalis in the treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery.

    Method
    From January 2010 to January 2016, a total of 39 UVFP patients who underwent Ansa Cervicalis anterior root-to-recurrent laryngeal nerve (RLN) anastomosis and who had suffered nerve disfunction for 6 to 24 months were enrolled as UVFP group.Another 39 age and gender matched normal subjects served as control group. Videostroboscopy, vocal function assessment (acoustic analysis, perceptual evaluation and maximum phonation time), and laryngeal electromyography were performed preoperatively and postoperatively for assessing surgery efficacy. Paired sample t test was used for statistical analysis.

    Result
    Videostroboscopic reports indicated that the glottic closure, vocal fold edge, vocal fold position, phase symmetry and regularity were significantly improved in the UVFP group (P 0.05, respectively). Both the postoperative GRBAS assessment and acoustic parameters were also significantly improved in the UVFP group, Pre-operative acoustic parameters/Post-operative acoustic parameters were 1.68±0.82/0.39±0.27, 10.08±2.56/4.58±2.96, 0.203±0.216/0.018±0.038, 5.96±1.92/17.42±4.11(P 0.05, respectively).

    Conclusion
    Delayed laryngeal reinnervation with the anterior root of Ansa Cervicalis, it can restore the physiological laryngeal phonatory function to the normal or a nearly normal voice quality, which is a feasible and effective approach for the treatment of thyroid surgery-related UVFP.

    Key words:
    Recurrent laryngeal nerve; Vocal cord paralysis; Ansa Cervicalis ventral root; Nerve repair

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  • Laryngeal reinnervation using Ansa Cervicalis for iatrogenic unilateral vocal fold paralysis
    Chinese Journal of General Surgery, 2012
    Co-Authors: Wei Wang, Donghui Chen, Shicai Chen, Hongliang Zheng

    Abstract:

    Objective To evaluate long-term outcome of laryngeal reinnervation using the main branch of the Ansa Cervicalis for the treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery. Methods From Oct.1990 to Jan.2010,a total of 325 UVFP patients who underwent main branch of Ansa Cervicalis-to-recurrent laryngeal nerve (RLN) anastomosis were enrolled in the study.We retrospectively analyzed the efficacy of the reinnervation surgery using videostroboscopy,vocal function assessment (acoustic analysis,perceptual evaluation and maximum phonation time ),and laryngeal electromyography. Results Videostroboscopy showed that the glottic closure,vocal fold edge,vocal fold position,phase symmetry and regularity were significantly improved postoperatively. The vocal function parameters (GRBAS scale,jitter,shimmer,noise to harmonics ratio and maximum phonation time) were also significantly improved postoperatively ( P < 0.01 ),as compared to corresponding preoperative values.Voice recovered to a normal level in 93.5% (304/325)patients,and the effective rate was 98.8% (321/325). Postoperative laryngeal electromyography confirmed successful reinnervation of laryngeal muscle. Condusions Laryngeal reinnervation using the main branch of Ansa Cervicalis is a feasible and effective approach for treatment of UVFP patients caused by thyroid surgery,with satisfactory long-term results.

    Key words:
    Recurrent laryngeal nerve; Vocal cord paralysis; Thyroidectomy; Reinnervation

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