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Emmanuel Akosung - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive constituents from Manilkara obovata (Sabine & G.Don) J.H.Hemsl.
    Natural product research, 2020
    Co-Authors: Emmanuel Akosung, Flavien A. A. Toze, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Hans-georg Stammler
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

  • bioactive constituents from manilkara obovata sabine g don j h hemsl
    Natural Product Research, 2020
    Co-Authors: Emmanuel Akosung, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Flavien A. A. Toze
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

Flavien A. A. Toze - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive constituents from Manilkara obovata (Sabine & G.Don) J.H.Hemsl.
    Natural product research, 2020
    Co-Authors: Emmanuel Akosung, Flavien A. A. Toze, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Hans-georg Stammler
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

  • bioactive constituents from manilkara obovata sabine g don j h hemsl
    Natural Product Research, 2020
    Co-Authors: Emmanuel Akosung, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Flavien A. A. Toze
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

Hans-georg Stammler - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive constituents from Manilkara obovata (Sabine & G.Don) J.H.Hemsl.
    Natural product research, 2020
    Co-Authors: Emmanuel Akosung, Flavien A. A. Toze, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Hans-georg Stammler
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

Sidonie Beactrice Kenmogne - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive constituents from Manilkara obovata (Sabine & G.Don) J.H.Hemsl.
    Natural product research, 2020
    Co-Authors: Emmanuel Akosung, Flavien A. A. Toze, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Hans-georg Stammler
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

  • bioactive constituents from manilkara obovata sabine g don j h hemsl
    Natural Product Research, 2020
    Co-Authors: Emmanuel Akosung, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Flavien A. A. Toze
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

Georges Bellier Tabekoueng - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive constituents from Manilkara obovata (Sabine & G.Don) J.H.Hemsl.
    Natural product research, 2020
    Co-Authors: Emmanuel Akosung, Flavien A. A. Toze, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Hans-georg Stammler
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.

  • bioactive constituents from manilkara obovata sabine g don j h hemsl
    Natural Product Research, 2020
    Co-Authors: Emmanuel Akosung, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses K. Langat, Georges Bellier Tabekoueng, Flavien A. A. Toze
    Abstract:

    The phytochemical investigation of the methanolic extracts of roots, stem bark, leaves and twigs of Manilkara obovata has led to the isolation of one new friedelane triterpene, lacefriedelic acid or 3β,23-dihydroxy D:A-friedooleanan-28-oic acid (1) and one new prenylated xanthone, lacexanthone or 4,7-dihydroxy-2,3,3,9,9-pentamethyl-2,2-dihydrofurano[2,3-a]pyrano[2,3-i]xanthen-13(9H)-one (2) alongside twenty-four known compounds. Compounds 1-11 are reported here for the first time from the genus Manilkara. The structures of all compounds were determined by spectroscopic analyses and X-ray crystallography. The methanolic extracts of twigs and leaves showed anti-oxidant activity of 93.2 and 91.1%, respectively, at 100 µg/mL when measured by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate), while the twig extract displayed 86.3% at 100 µg/mL against the urease inhibition assay. Some isolated compounds (1-4, 15 and 20) showed significant to moderate anti-oxidant activity and urease inhibition assay. It is estimated that significantly active Anti-Oxidants and urease inhibitors metabolized by the plant may find future application in food industry.