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Muhammad Wahizul Haswan Abdul Aziz – One of the best experts on this subject based on the ideXlab platform.

  • Anticariogenic properties of solanum ferox l ethanol extract
    Annals of dentistry, 2019
    Co-Authors: Siti Zaleha Raduan, Khairah Nasrin Abdul Khalid, Mark Fitchell Ak Jihek, Sivagami Ganasan, Umi Syazana Salim, Muhammad Wahizul Haswan Abdul Aziz

    Abstract:

    Solanum ferox L. is a plant species which belongs to the Sola-naceae family and the genus Solanum. The Solanum genus was found to exhibit Anticariogenic activity and was tradition-ally used to treat oral diseases. However there are no scien-tific studies done specifically for Solanum ferox L. Hence the aim of the study is to determine the Anticariogenic properties of flesh and leaf of ethanolic extract of Solanum ferox L. Alka-loids, flavonoids and tannins were detected in the leaf etha-nolic extract via preliminary phytochemical screening. The presence of these phytochemicals may contribute to the Anticariogenic activity. Treatment with different concentra-tions of flesh and leaf of ethanolic extract were used against Streptococcus pyogenes and Staphylococcus aureus via the
    method of agar well diffusion to indicate zones of inhibition. The antibiofilm activity of the flesh and leaf ethanolic extracts was tested. The flesh and leaf ethanolic extracts possess sig-nificant (p<0.05) dose-dependent on antimicrobial activity and positive antibiofilm activity against respective pathogens. Flesh ethanolic extract has stronger Anticariogenic activity compared to leaf ethanolic extract against Staphylococcus aureus. Streptococcus pyogenes exhibited higher susceptibil-ity as compared to Staphylococcus aureus. In conclusion, it has been shown that the ethanolic extract of Solanum ferox L. exhibit Anticariogenic properties against Streptococus py-ogenes and Staphylococcus aureus

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  • Anticariogenic properties of Solanum ferox L. ethanol extract
    Annals of Dentistry, 2019
    Co-Authors: Siti Zaleha Raduan, Khairah Nasrin Abdul Khalid, Mark Fitchell Ak Jihek, Sivagami Ganasan, Umi Syazana Salim, Muhammad Wahizul Haswan Abdul Aziz

    Abstract:

    Solanum ferox L. is a plant species which belongs to the Sola-naceae family and the genus Solanum. The Solanum genus was found to exhibit Anticariogenic activity and was tradition-ally used to treat oral diseases. However there are no scien-tific studies done specifically for Solanum ferox L. Hence the aim of the study is to determine the Anticariogenic properties of flesh and leaf of ethanolic extract of Solanum ferox L. Alka-loids, flavonoids and tannins were detected in the leaf etha-nolic extract via preliminary phytochemical screening. The presence of these phytochemicals may contribute to the Anticariogenic activity. Treatment with different concentra-tions of flesh and leaf of ethanolic extract were used against Streptococcus pyogenes and Staphylococcus aureus via the
    method of agar well diffusion to indicate zones of inhibition. The antibiofilm activity of the flesh and leaf ethanolic extracts was tested. The flesh and leaf ethanolic extracts possess sig-nificant (p

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Siti Zaleha Raduan – One of the best experts on this subject based on the ideXlab platform.

  • Anticariogenic properties of solanum ferox l ethanol extract
    Annals of dentistry, 2019
    Co-Authors: Siti Zaleha Raduan, Khairah Nasrin Abdul Khalid, Mark Fitchell Ak Jihek, Sivagami Ganasan, Umi Syazana Salim, Muhammad Wahizul Haswan Abdul Aziz

    Abstract:

    Solanum ferox L. is a plant species which belongs to the Sola-naceae family and the genus Solanum. The Solanum genus was found to exhibit Anticariogenic activity and was tradition-ally used to treat oral diseases. However there are no scien-tific studies done specifically for Solanum ferox L. Hence the aim of the study is to determine the Anticariogenic properties of flesh and leaf of ethanolic extract of Solanum ferox L. Alka-loids, flavonoids and tannins were detected in the leaf etha-nolic extract via preliminary phytochemical screening. The presence of these phytochemicals may contribute to the Anticariogenic activity. Treatment with different concentra-tions of flesh and leaf of ethanolic extract were used against Streptococcus pyogenes and Staphylococcus aureus via the
    method of agar well diffusion to indicate zones of inhibition. The antibiofilm activity of the flesh and leaf ethanolic extracts was tested. The flesh and leaf ethanolic extracts possess sig-nificant (p<0.05) dose-dependent on antimicrobial activity and positive antibiofilm activity against respective pathogens. Flesh ethanolic extract has stronger Anticariogenic activity compared to leaf ethanolic extract against Staphylococcus aureus. Streptococcus pyogenes exhibited higher susceptibil-ity as compared to Staphylococcus aureus. In conclusion, it has been shown that the ethanolic extract of Solanum ferox L. exhibit Anticariogenic properties against Streptococus py-ogenes and Staphylococcus aureus

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  • Anticariogenic properties of Solanum ferox L. ethanol extract
    Annals of Dentistry, 2019
    Co-Authors: Siti Zaleha Raduan, Khairah Nasrin Abdul Khalid, Mark Fitchell Ak Jihek, Sivagami Ganasan, Umi Syazana Salim, Muhammad Wahizul Haswan Abdul Aziz

    Abstract:

    Solanum ferox L. is a plant species which belongs to the Sola-naceae family and the genus Solanum. The Solanum genus was found to exhibit Anticariogenic activity and was tradition-ally used to treat oral diseases. However there are no scien-tific studies done specifically for Solanum ferox L. Hence the aim of the study is to determine the Anticariogenic properties of flesh and leaf of ethanolic extract of Solanum ferox L. Alka-loids, flavonoids and tannins were detected in the leaf etha-nolic extract via preliminary phytochemical screening. The presence of these phytochemicals may contribute to the Anticariogenic activity. Treatment with different concentra-tions of flesh and leaf of ethanolic extract were used against Streptococcus pyogenes and Staphylococcus aureus via the
    method of agar well diffusion to indicate zones of inhibition. The antibiofilm activity of the flesh and leaf ethanolic extracts was tested. The flesh and leaf ethanolic extracts possess sig-nificant (p

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Jaekwan Hwang – One of the best experts on this subject based on the ideXlab platform.

  • Anticariogenic activity of macelignan isolated from myristica fragrans nutmeg against streptococcus mutans
    Phytomedicine, 2006
    Co-Authors: J Y Chung, J H Choo, Moonhyoung Lee, Jaekwan Hwang

    Abstract:

    Abstract The occurrence of dental caries is mainly associated with oral pathogens, especially cariogenic Streptococcus mutans. Preliminary antibacterial screening revealed that the extract of Myristica fragrans, widely cultivated for the spice and flavor of foods, possessed strong inhibitory activity against S. mutans. The Anticariogenic compound was successfully isolated from the methanol extract of M. fragrans by repeated silica gel chromatography, and its structure was identified as macelignan by instrumental analysis using 1D-NMR, 2D-NMR and EI-MS. The minimum inhibitory concentration (MIC) of macelignan against S. mutans was 3.9 μg/ml, which was much lower than those of other natural Anticariogenic agents such as 15.6 μg/ml of sanguinarine, 250 μg/ml of eucalyptol, 500 μg/ml of menthol and thymol, and 1000 μg/ml of methyl salicylate. Macelignan also possessed preferential activity against other oral microorganisms such as Streptococcus sobrinus, Streptococcus salivarius, Streptococcus sanguis, Lactobacillus acidophilus and Lactobacillus casei in the MIC range of 2–31.3 μg/ml. In particular, the bactericidal test showed that macelignan, at a concentration of 20 μg/ml, completely inactivated S. mutans in 1 min. The specific activity and fast-effectiveness of macelignan against oral bacteria strongly suggest that it could be employed as a natural antibacterial agent in functional foods or oral care products.

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  • Anticariogenic activity of some tropical medicinal plants against streptococcus mutans
    Fitoterapia, 2004
    Co-Authors: Jaekwan Hwang, Jaeseok Shim, Jaeyoun Chung

    Abstract:

    Abstract The methanol extracts of five tropical plants, Baeckea frutescens , Glycyrrhiza glabra , Kaempferia pandurata , Physalis angulata and Quercus infectoria , exhibited potent antibacterial activity against the cariogenic bacterium Streptococcus mutans . In particular, G. glabra , K. pandurata and P. angulata conferred fast killing bactericidal effect against S. mutans in 2 min at 50 μg/ml of extract concentration.

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