Antidiarrheal Agent - Explore the Science & Experts | ideXlab

Scan Science and Technology

Contact Leading Edge Experts & Companies

Antidiarrheal Agent

The Experts below are selected from a list of 1020 Experts worldwide ranked by ideXlab platform

Antidiarrheal Agent – Free Register to Access Experts & Abstracts

Seewaboon Sireeratawong – One of the best experts on this subject based on the ideXlab platform.

  • Effect of Tri-sa-maw recipe on gastrointestinal regulation and motility. .
    Journal of the Medical Association of Thailand Chotmaihet thangphaet, 2015
    Co-Authors: Supaporn Wannasiri, Kanjana Jaijoy, Natthakarn Chiranthanut, Noppamas Soonthornchareonnon, Seewaboon Sireeratawong
    Abstract:

    Background: Tri-sa-maw recipe is comprised of equal proportions of three herbal fruits, including Terminalia chebula Retz., Terminalia sp. and Terminalia bellirica Roxb. The traditional use of this recipe has been reported as a medication for fever, expectorant, relief of tightness in the stomach, laxative and Antidiarrheal Agent. Objective: To study the effects of Tri-sa-maw recipe extract on gastrointestinal tract in both in vitro and in vivo. Material and Method: Gastrointestinal effect of Tri-sa-maw recipe was studied by using two in vivo models (gastric emptying, gastrointestinal transit) and in vitro isolated guinea pig ileum experiment. Results: Tri-sa-maw recipe showed both stimulatory and inhibitory effects on the stomach function. Not only did the extract at the dose of 1,000 mg/kg inhibit the gastric emptying time, but also stimulate the movement of the digestive tract by increasing the mobility of charcoal. In the isolated guinea pig ileum experiment, the extract at low concentration (0.1 ng/mL) induced the contraction of isolated guinea pig ileum. However, the stimulation effect on contractions of isolated guinea pig ileum was very much decreased at the high concentration (0.2-1 ng/mL) of the extract. Conclusion: The findings of this study support to traditional uses of Tri-sa-maw recipe as a laxative and Antidiarrheal Agent. Keywords: Tri-sa-maw recipe, Gastric emptying, Intestinal transit

  • Effect of Tri-sa-maw recipe on gastrointestinal regulation and motility. .
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015
    Co-Authors: Supaporn Wannasiri, Kanjana Jaijoy, Natthakarn Chiranthanut, Noppamas Soonthornchareonnon, Seewaboon Sireeratawong
    Abstract:

    Tri-sa-maw recipe is comprised ofequal proportions of three herbal fruits, including Terminalia chebula Retz., Terminalia sp. and Terminalia bellirica Roxb. The traditional use of this recipe has been reported as a medication for fever; expectorant, relief of tightness in the stomach, laxative and Antidiarrheal Agent. To study the effects of Tri-sa-maw recipe extract on gastrointestinal tract in both in vitro and in vivo. Gastrointestinal effect of Tri-sa-maw recipe was studied by using two in vivo models (gastric emptying, gastrointestinal transit) and in vitro isolated guinea pig ileum experiment. Tri-sa-maw recipe showed both stimulatory and inhibitory effects on the stomach function. Not only did the extract at the dose of 1,000 mg/kg inhibit the gastric emptying time, but also stimulate the movement of the digestive tract by increasing the mobility of charcoal. In the isolated guinea pig ileum experiment, the extract at low concentration (0.1 ng/mL) induced the contraction of isolated guinea pig ileum. However the stimulation effect on contractions of isolated guineapig ileum was very much decreased at the high concentration (0.2-1 ng/mL) of the extract. The findings of this study support to traditional uses of Tri-sa-maw recipe as a laxative and Antidiarrheal Agent.

Dwi Febiyanti – One of the best experts on this subject based on the ideXlab platform.

  • POTENSI BAKTERI ASAM LAKTAT PROBIOTIK INDIGENUS SEBAGAI ANTIDIARE DAN IMUNOMODULATOR [Potency of Indigenous Probiotic Lactic Acid Bacteria as Antidiarrheal Agent and Immunomodulator]
    Jurnal Teknologi dan Industri Pangan, 2011
    Co-Authors: Made Astawan, Tutik Wresdiyati, Irma Isnafia Arief, Dwi Febiyanti
    Abstract:

    The aim of the study was to observe the ability of indigenous probiotic lactic acid bacteria (LAB) Lactobacillus plantarum 2C12 and Lactobacillus fermentum 2B4 as Antidiarrheal Agent in rats infected by Enteropathogenic Escherichia coli (EPEC), and also to observe their effect as immunomodulator (malonaldehyde level and proliferation of lymphocyte cell). A total of 90 male Sprague Dawley rats were used for this study and divided into 6 groups i.e.: (1) Negative Control (not infected with of EPEC), (2) LAB L. plantarum 2C12, (3) LAB L. fermentum 2B4, (4) LAB L. plantarum 2C12 + EPEC, (5) LAB L. fermentum 2B4 + EPEC, and (6) Positive Control (infected with EPEC). The treatment of LAB was undertaken from 1 st -21 st day, while infection of EPEC using 10 6 cfu/ml per day was undertaken during 8 th -14 th day. Groups administered with LAB L. plantarum 2C12 + EPEC, LAB L. fermentum 2B4 + EPEC, and positive control, showed decreased body weight during 12 th -21 st day. At the 21 st day, positive control group underwent acute diarrhea (fecal water content was 68.2 % b/b). Statistical analysis with Duncan Test showed that the treatment given to six groups of rats gave significant effect (p

  • potensi bakteri asam laktat probiotik indigenus sebagai antidiare dan imunomodulator potency of indigenous probiotic lactic acid bacteria as Antidiarrheal Agent and immunomodulator
    Jurnal Teknologi dan Industri Pangan, 2011
    Co-Authors: Made Astawan, Tutik Wresdiyati, Irma Isnafia Arief, Dwi Febiyanti
    Abstract:

    The aim of the study was to observe the ability of indigenous probiotic lactic acid bacteria (LAB) Lactobacillus plantarum 2C12 and Lactobacillus fermentum 2B4 as Antidiarrheal Agent in rats infected by Enteropathogenic Escherichia coli (EPEC), and also to observe their effect as immunomodulator (malonaldehyde level and proliferation of lymphocyte cell). A total of 90 male Sprague Dawley rats were used for this study and divided into 6 groups i.e.: (1) Negative Control (not infected with of EPEC), (2) LAB L. plantarum 2C12, (3) LAB L. fermentum 2B4, (4) LAB L. plantarum 2C12 + EPEC, (5) LAB L. fermentum 2B4 + EPEC, and (6) Positive Control (infected with EPEC). The treatment of LAB was undertaken from 1 st -21 st day, while infection of EPEC using 10 6 cfu/ml per day was undertaken during 8 th -14 th day. Groups administered with LAB L. plantarum 2C12 + EPEC, LAB L. fermentum 2B4 + EPEC, and positive control, showed decreased body weight during 12 th -21 st day. At the 21 st day, positive control group underwent acute diarrhea (fecal water content was 68.2 % b/b). Statistical analysis with Duncan Test showed that the treatment given to six groups of rats gave significant effect (p<0.05) toward PER value, number of lymphocyte cells and malonaldehyde level in liver and kidney of the rats.

Supaporn Wannasiri – One of the best experts on this subject based on the ideXlab platform.

  • Effect of Tri-sa-maw recipe on gastrointestinal regulation and motility. .
    Journal of the Medical Association of Thailand Chotmaihet thangphaet, 2015
    Co-Authors: Supaporn Wannasiri, Kanjana Jaijoy, Natthakarn Chiranthanut, Noppamas Soonthornchareonnon, Seewaboon Sireeratawong
    Abstract:

    Background: Tri-sa-maw recipe is comprised of equal proportions of three herbal fruits, including Terminalia chebula Retz., Terminalia sp. and Terminalia bellirica Roxb. The traditional use of this recipe has been reported as a medication for fever, expectorant, relief of tightness in the stomach, laxative and Antidiarrheal Agent. Objective: To study the effects of Tri-sa-maw recipe extract on gastrointestinal tract in both in vitro and in vivo. Material and Method: Gastrointestinal effect of Tri-sa-maw recipe was studied by using two in vivo models (gastric emptying, gastrointestinal transit) and in vitro isolated guinea pig ileum experiment. Results: Tri-sa-maw recipe showed both stimulatory and inhibitory effects on the stomach function. Not only did the extract at the dose of 1,000 mg/kg inhibit the gastric emptying time, but also stimulate the movement of the digestive tract by increasing the mobility of charcoal. In the isolated guinea pig ileum experiment, the extract at low concentration (0.1 ng/mL) induced the contraction of isolated guinea pig ileum. However, the stimulation effect on contractions of isolated guinea pig ileum was very much decreased at the high concentration (0.2-1 ng/mL) of the extract. Conclusion: The findings of this study support to traditional uses of Tri-sa-maw recipe as a laxative and Antidiarrheal Agent. Keywords: Tri-sa-maw recipe, Gastric emptying, Intestinal transit

  • Effect of Tri-sa-maw recipe on gastrointestinal regulation and motility. .
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015
    Co-Authors: Supaporn Wannasiri, Kanjana Jaijoy, Natthakarn Chiranthanut, Noppamas Soonthornchareonnon, Seewaboon Sireeratawong
    Abstract:

    Tri-sa-maw recipe is comprised ofequal proportions of three herbal fruits, including Terminalia chebula Retz., Terminalia sp. and Terminalia bellirica Roxb. The traditional use of this recipe has been reported as a medication for fever; expectorant, relief of tightness in the stomach, laxative and Antidiarrheal Agent. To study the effects of Tri-sa-maw recipe extract on gastrointestinal tract in both in vitro and in vivo. Gastrointestinal effect of Tri-sa-maw recipe was studied by using two in vivo models (gastric emptying, gastrointestinal transit) and in vitro isolated guinea pig ileum experiment. Tri-sa-maw recipe showed both stimulatory and inhibitory effects on the stomach function. Not only did the extract at the dose of 1,000 mg/kg inhibit the gastric emptying time, but also stimulate the movement of the digestive tract by increasing the mobility of charcoal. In the isolated guinea pig ileum experiment, the extract at low concentration (0.1 ng/mL) induced the contraction of isolated guinea pig ileum. However the stimulation effect on contractions of isolated guineapig ileum was very much decreased at the high concentration (0.2-1 ng/mL) of the extract. The findings of this study support to traditional uses of Tri-sa-maw recipe as a laxative and Antidiarrheal Agent.

Beverley Greenwood-van Meerveld – One of the best experts on this subject based on the ideXlab platform.

  • Effects of Seirogan (Wood Creosote) on Propulsive Colonic Motility and Stool Characteristics in Ambulatory Mini-Pigs
    Digestive Diseases and Sciences, 2002
    Co-Authors: T. Kuge, K. Venkova, Beverley Greenwood-van Meerveld
    Abstract:

    Our goal was to determine whether Seirogan, an herbal medicine used as an Antidiarrheal Agent, modifies colonic function, including motility. Experiments were performed on four female Yucatan mini-pigs with established permanent cecal fistulas providing direct access to the colon. Long-term recordings of proximal colonic motility were accomplished by a solid-state probe (six pressure ports 10 cm apart), and a motility index was calculated. Stool viscosity was also measured. The laxative bisacodyl (15 mg/kg) was used to induce colonic motility (increase in motility index) and stool softening, prior to investigating the effect of Seirogan (2–15 mg/kg per os twice a day) or a vehicle control. Seirogan (15 mg/kg), but not the placebo, reversed the bisacodyl-induced stool softening and restored the motility index to normal values by reducing the number of propagating contractions. Taken together the results suggest that inhibition of proximal colonic motility by Seirogan may contribute to its Antidiarrheal action.

Made Astawan – One of the best experts on this subject based on the ideXlab platform.

  • POTENSI BAKTERI ASAM LAKTAT PROBIOTIK INDIGENUS SEBAGAI ANTIDIARE DAN IMUNOMODULATOR [Potency of Indigenous Probiotic Lactic Acid Bacteria as Antidiarrheal Agent and Immunomodulator]
    Jurnal Teknologi dan Industri Pangan, 2011
    Co-Authors: Made Astawan, Tutik Wresdiyati, Irma Isnafia Arief, Dwi Febiyanti
    Abstract:

    The aim of the study was to observe the ability of indigenous probiotic lactic acid bacteria (LAB) Lactobacillus plantarum 2C12 and Lactobacillus fermentum 2B4 as Antidiarrheal Agent in rats infected by Enteropathogenic Escherichia coli (EPEC), and also to observe their effect as immunomodulator (malonaldehyde level and proliferation of lymphocyte cell). A total of 90 male Sprague Dawley rats were used for this study and divided into 6 groups i.e.: (1) Negative Control (not infected with of EPEC), (2) LAB L. plantarum 2C12, (3) LAB L. fermentum 2B4, (4) LAB L. plantarum 2C12 + EPEC, (5) LAB L. fermentum 2B4 + EPEC, and (6) Positive Control (infected with EPEC). The treatment of LAB was undertaken from 1 st -21 st day, while infection of EPEC using 10 6 cfu/ml per day was undertaken during 8 th -14 th day. Groups administered with LAB L. plantarum 2C12 + EPEC, LAB L. fermentum 2B4 + EPEC, and positive control, showed decreased body weight during 12 th -21 st day. At the 21 st day, positive control group underwent acute diarrhea (fecal water content was 68.2 % b/b). Statistical analysis with Duncan Test showed that the treatment given to six groups of rats gave significant effect (p

  • potensi bakteri asam laktat probiotik indigenus sebagai antidiare dan imunomodulator potency of indigenous probiotic lactic acid bacteria as Antidiarrheal Agent and immunomodulator
    Jurnal Teknologi dan Industri Pangan, 2011
    Co-Authors: Made Astawan, Tutik Wresdiyati, Irma Isnafia Arief, Dwi Febiyanti
    Abstract:

    The aim of the study was to observe the ability of indigenous probiotic lactic acid bacteria (LAB) Lactobacillus plantarum 2C12 and Lactobacillus fermentum 2B4 as Antidiarrheal Agent in rats infected by Enteropathogenic Escherichia coli (EPEC), and also to observe their effect as immunomodulator (malonaldehyde level and proliferation of lymphocyte cell). A total of 90 male Sprague Dawley rats were used for this study and divided into 6 groups i.e.: (1) Negative Control (not infected with of EPEC), (2) LAB L. plantarum 2C12, (3) LAB L. fermentum 2B4, (4) LAB L. plantarum 2C12 + EPEC, (5) LAB L. fermentum 2B4 + EPEC, and (6) Positive Control (infected with EPEC). The treatment of LAB was undertaken from 1 st -21 st day, while infection of EPEC using 10 6 cfu/ml per day was undertaken during 8 th -14 th day. Groups administered with LAB L. plantarum 2C12 + EPEC, LAB L. fermentum 2B4 + EPEC, and positive control, showed decreased body weight during 12 th -21 st day. At the 21 st day, positive control group underwent acute diarrhea (fecal water content was 68.2 % b/b). Statistical analysis with Duncan Test showed that the treatment given to six groups of rats gave significant effect (p<0.05) toward PER value, number of lymphocyte cells and malonaldehyde level in liver and kidney of the rats.