The Experts below are selected from a list of 12 Experts worldwide ranked by ideXlab platform

G Frutos - One of the best experts on this subject based on the ideXlab platform.

  • effectiveness of rosmarinus officinalis essential oil as Antihypotensive Agent in primary hypotensive patients and its influence on health related quality of life
    Journal of Ethnopharmacology, 2014
    Co-Authors: L F Fernandez, O M Palomino, G Frutos
    Abstract:

    Abstract Ethnopharmacological relevance To study Rosmarinus officinalis (Rosemary) essential oil effect on primary hypotension and its influence on both physical and psychological aspects responsible for health-related quality of life (HRQOL) of patients. Methodology Thirty-two patients with diagnosed hypotension were recruited between March 2007 and September 2008 for a prospective study for 72 weeks in a Spanish pharmacy. Clinical evaluation was carried out through the control of systolic and diastolic blood pressure levels (SBP and DBP, respectively) according to the International Standards from the American Society of Hypertension. HRQOL data were recorded within the SF-36 Health Survey ® questionnaire throughout the study. Statistical methods were used as the essential tools to evaluate the effectiveness of Rosemary essential oil and to assess the relationship between the two quantitative variables (SBP and DBP) and scores from physical and mental summary components (PSC and MSC) obtained from the SF-36 Health Survey. Results Both blood pressure variables of SBP and DBP reflect the clinically significant Antihypotensive effect of Rosemary essential oil that was maintained throughout the treatment period. After validation of the use of the questionnaire (Cronbach's alpha coefficient>0.82), statistically significant differences have been found between pre-treatment and post-treatment values of PSC and MSC, which indicate an improvement in these parameters that is directly related to the variation in blood pressure values. Conclusions The increase achieved in blood pressure values after administration of Rosemary essential oil is clinically significant. The results obtained from this prospective clinical trial prove the effectiveness of statistical methodology as a new approach to explain the Antihypotensive effect of rosemary essential oil and its relationship with the improvement in patients' quality of life.

L F Fernandez - One of the best experts on this subject based on the ideXlab platform.

  • effectiveness of rosmarinus officinalis essential oil as Antihypotensive Agent in primary hypotensive patients and its influence on health related quality of life
    Journal of Ethnopharmacology, 2014
    Co-Authors: L F Fernandez, O M Palomino, G Frutos
    Abstract:

    Abstract Ethnopharmacological relevance To study Rosmarinus officinalis (Rosemary) essential oil effect on primary hypotension and its influence on both physical and psychological aspects responsible for health-related quality of life (HRQOL) of patients. Methodology Thirty-two patients with diagnosed hypotension were recruited between March 2007 and September 2008 for a prospective study for 72 weeks in a Spanish pharmacy. Clinical evaluation was carried out through the control of systolic and diastolic blood pressure levels (SBP and DBP, respectively) according to the International Standards from the American Society of Hypertension. HRQOL data were recorded within the SF-36 Health Survey ® questionnaire throughout the study. Statistical methods were used as the essential tools to evaluate the effectiveness of Rosemary essential oil and to assess the relationship between the two quantitative variables (SBP and DBP) and scores from physical and mental summary components (PSC and MSC) obtained from the SF-36 Health Survey. Results Both blood pressure variables of SBP and DBP reflect the clinically significant Antihypotensive effect of Rosemary essential oil that was maintained throughout the treatment period. After validation of the use of the questionnaire (Cronbach's alpha coefficient>0.82), statistically significant differences have been found between pre-treatment and post-treatment values of PSC and MSC, which indicate an improvement in these parameters that is directly related to the variation in blood pressure values. Conclusions The increase achieved in blood pressure values after administration of Rosemary essential oil is clinically significant. The results obtained from this prospective clinical trial prove the effectiveness of statistical methodology as a new approach to explain the Antihypotensive effect of rosemary essential oil and its relationship with the improvement in patients' quality of life.

Ming Yie Liu - One of the best experts on this subject based on the ideXlab platform.

  • the elucidation of epinephrine as an Antihypotensive Agent in abamectin intoxication
    Human & Experimental Toxicology, 2003
    Co-Authors: Dur Zong Hsu, Po Jung Chiang, Ching Hung Hsu, Bu Miin Huang, Jou Fang Deng, Ming Yie Liu
    Abstract:

    Abamectin (ABM) has been used in some suicidal attempt cases in recent years. ABM-intoxicated patients demonstrate low mean arterial pressure (MAP) and commonly treated with catecholamine to burst MAPs in their intensive cares. This investigation examined roles of epinephrine on MAP, heart rate (HR), and therein baroreflex sensitivity (BRS-HR/MAP) during ABM intoxication in rats. Oral application of ABM (20 mg/kg) induced an increase in HR and BRS accompanied by a decrease in MAP. These effects, except for on BRS, were abolished by concomitant epinephrine injection [100 mg/ kg, subcutaneously (s.c.)]. ABM also induced an increase in serum nitric oxide levels, which was partly antagonized by epinephrine. In summary, oral application of ABM induced a decrease in MAP. Administration of epinephrine sustained the normal range of MAP via nitric oxide regulation, but it has no effect on BRS due to the synchronous changes of MAP and HR in ABMintoxicated rats.

O M Palomino - One of the best experts on this subject based on the ideXlab platform.

  • effectiveness of rosmarinus officinalis essential oil as Antihypotensive Agent in primary hypotensive patients and its influence on health related quality of life
    Journal of Ethnopharmacology, 2014
    Co-Authors: L F Fernandez, O M Palomino, G Frutos
    Abstract:

    Abstract Ethnopharmacological relevance To study Rosmarinus officinalis (Rosemary) essential oil effect on primary hypotension and its influence on both physical and psychological aspects responsible for health-related quality of life (HRQOL) of patients. Methodology Thirty-two patients with diagnosed hypotension were recruited between March 2007 and September 2008 for a prospective study for 72 weeks in a Spanish pharmacy. Clinical evaluation was carried out through the control of systolic and diastolic blood pressure levels (SBP and DBP, respectively) according to the International Standards from the American Society of Hypertension. HRQOL data were recorded within the SF-36 Health Survey ® questionnaire throughout the study. Statistical methods were used as the essential tools to evaluate the effectiveness of Rosemary essential oil and to assess the relationship between the two quantitative variables (SBP and DBP) and scores from physical and mental summary components (PSC and MSC) obtained from the SF-36 Health Survey. Results Both blood pressure variables of SBP and DBP reflect the clinically significant Antihypotensive effect of Rosemary essential oil that was maintained throughout the treatment period. After validation of the use of the questionnaire (Cronbach's alpha coefficient>0.82), statistically significant differences have been found between pre-treatment and post-treatment values of PSC and MSC, which indicate an improvement in these parameters that is directly related to the variation in blood pressure values. Conclusions The increase achieved in blood pressure values after administration of Rosemary essential oil is clinically significant. The results obtained from this prospective clinical trial prove the effectiveness of statistical methodology as a new approach to explain the Antihypotensive effect of rosemary essential oil and its relationship with the improvement in patients' quality of life.

Dur Zong Hsu - One of the best experts on this subject based on the ideXlab platform.

  • the elucidation of epinephrine as an Antihypotensive Agent in abamectin intoxication
    Human & Experimental Toxicology, 2003
    Co-Authors: Dur Zong Hsu, Po Jung Chiang, Ching Hung Hsu, Bu Miin Huang, Jou Fang Deng, Ming Yie Liu
    Abstract:

    Abamectin (ABM) has been used in some suicidal attempt cases in recent years. ABM-intoxicated patients demonstrate low mean arterial pressure (MAP) and commonly treated with catecholamine to burst MAPs in their intensive cares. This investigation examined roles of epinephrine on MAP, heart rate (HR), and therein baroreflex sensitivity (BRS-HR/MAP) during ABM intoxication in rats. Oral application of ABM (20 mg/kg) induced an increase in HR and BRS accompanied by a decrease in MAP. These effects, except for on BRS, were abolished by concomitant epinephrine injection [100 mg/ kg, subcutaneously (s.c.)]. ABM also induced an increase in serum nitric oxide levels, which was partly antagonized by epinephrine. In summary, oral application of ABM induced a decrease in MAP. Administration of epinephrine sustained the normal range of MAP via nitric oxide regulation, but it has no effect on BRS due to the synchronous changes of MAP and HR in ABMintoxicated rats.