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Antimicrobial Agent

The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform

Berhanu Andualem – 1st expert on this subject based on the ideXlab platform

  • The role of spices and lactic acid bacteria as Antimicrobial Agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)
    Journal of Food Science and Technology, 2015
    Co-Authors: Tsehayneh Geremew, Ameha Kebede, Berhanu Andualem


    Spices and lactic acid bacteria have natural Antimicrobial substances and organic compounds having antagonistic activity against microorganisms. The objective of this study was to investigate the role of spices and lactic acid bacteria as Antimicrobial Agent to extend the shelf life of metata ayib . Antimicrobial activities of spices and lactic acid bacteria (LAB) filtrates were determined by agar well diffusion method against E. coli , S. aureus , S. flexneri and S. peumoniae . AAntimicrobial activity of garlic was found to be the most effective against all the tested pathogens. Inhibition zones of garlic extract against all pathogens was significantly ( P  ≤ 0.05) greater than the remaining spice extracts. Inhibition zones (12.50 ± 1.00 to 15.50 ± 1.00 mm) of ginger and R. graveolens ethanol extracts against all tested pathogens were significantly ( P  ≤ 0.05) greater than the remaining solvent extracts. Inhibition zone of O. basilicum ethanol extract against all pathogenic bacteria was significantly ( p  ≤ 0.05) greater than hexane and acetone extracts. Lactobacillus isolates were shown the highest Antimicrobial activity than the other LAB isolates against all pathogens. The synergistic effect of spices together with LAB might be contributed a lot to preserve and extend shelf life of metata ayib. Their Antimicrobial activity can reduce the risk of spoilage and pathogenesis. The possible reason of LAB isolates was may be due to production of lactic acid, acetic acid and secondary metabolites like bacteriocins. Aseptic processing of traditional cottage cheese ( ayib ) is by far needed to minimize risks associated during consumption of metata ayib .

Adam J Friedman – 2nd expert on this subject based on the ideXlab platform

  • nitric oxide nanoparticle technology a novel Antimicrobial Agent in the context of current treatment of skin and soft tissue infection
    The Journal of clinical and aesthetic dermatology, 2010
    Co-Authors: Laura Englander, Adam J Friedman


    Staphylococcus aureus infections account for the majority of skin and soft tissue infections in the United States. Staphylococcus aureus is rapidly evolving resistance to contemporary topical as well as systemic antibiotics. Alternatives to current treatment options for skin and soft tissue infections are needed for more effective treatment now and in the future. Nitric oxide’s proven roles in both wound repair and as an Antimicrobial Agent make it an excellent candidate for the treatment of skin infections. Recent attempts at novel nitric oxide therapies, in the form of nitric oxide donors, have shown limited potential in treating cutaneous infection. However, more recent developments in nitric oxide delivery, using nitric oxide nanoparticle technology, demonstrate substantial promise in the promotion of wound repair and eradication of skin and soft tissue infections.

Michael Wilson – 3rd expert on this subject based on the ideXlab platform

  • in vivo killing of staphylococcus aureus using a light activated Antimicrobial Agent
    BMC Microbiology, 2009
    Co-Authors: Parjam S Zolfaghari, Samantha Packer, Mervyn Singer, Sean P Nair, J H Bennett, Cale Street, Michael Wilson


    The widespread problem of antibiotic resistance in pathogens such as Staphylococcus aureus has prompted the search for new Antimicrobial approaches. In this study we report for the first time the use of a light-activated Antimicrobial Agent, methylene blue, to kill an epidemic methicillin-resistant Staphylococcus aureus (EMRSA-16) strain in two mouse wound models.