The Experts below are selected from a list of 807 Experts worldwide ranked by ideXlab platform
Sumith Abeygunasekara - One of the best experts on this subject based on the ideXlab platform.
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bilateral renal artery thrombosis in inherited thrombophilia a rare cause of acute kidney injury
International Journal of Nephrology and Renovascular Disease, 2014Co-Authors: Kate Wiles, Laura Hastings, Vasantha Muthu Muthuppalaniappan, Muhammad Hanif, Sumith AbeygunasekaraAbstract:We describe the case of a 47-year-old man who developed significant acute, and subsequently chronic, kidney injury due to bilateral renal infarction. This occurred in the context of a combined inherited thrombophilia including Antithrombin III Deficiency and a prothrombin gene mutation. Bilateral renal artery thrombosis developed despite prophylactic treatment for thromboembolism. Arterial thrombosis is rare in the context of inherited thrombophilia and bilateral renal infarction is an unusual cause of acute kidney injury. Bilateral renal infarction due to primary renal artery thrombosis has not been previously described in Antithrombin III Deficiency, either as an isolated defect or in combination with other hereditary thrombophilia.
Kate Wiles - One of the best experts on this subject based on the ideXlab platform.
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bilateral renal artery thrombosis in inherited thrombophilia a rare cause of acute kidney injury
International Journal of Nephrology and Renovascular Disease, 2014Co-Authors: Kate Wiles, Laura Hastings, Vasantha Muthu Muthuppalaniappan, Muhammad Hanif, Sumith AbeygunasekaraAbstract:We describe the case of a 47-year-old man who developed significant acute, and subsequently chronic, kidney injury due to bilateral renal infarction. This occurred in the context of a combined inherited thrombophilia including Antithrombin III Deficiency and a prothrombin gene mutation. Bilateral renal artery thrombosis developed despite prophylactic treatment for thromboembolism. Arterial thrombosis is rare in the context of inherited thrombophilia and bilateral renal infarction is an unusual cause of acute kidney injury. Bilateral renal infarction due to primary renal artery thrombosis has not been previously described in Antithrombin III Deficiency, either as an isolated defect or in combination with other hereditary thrombophilia.
Charles J Glueck - One of the best experts on this subject based on the ideXlab platform.
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95 heritable thrombophilia and development of thromboembolic disease following total hip arthroplasty
Journal of Investigative Medicine, 2005Co-Authors: Eduardo A Salvati, Babette B Weksler, Ping Wang, Gonzalez A Della Valle, G Westrich, A J Rang, L Specht, Charles J GlueckAbstract:We assessed whether heritable thrombophilia was more common in cases with symptomatic venous thromboembolism (VTE) after total hip replacement (THA) than among asymptomatic controls without VTE. After THA, 20 cases with deep venous thrombosis (DVT) documented by magnetic resonance venogram (MRV), and 23 with pulmonary embolism (PE) documented by ventilation/perfusion or spiral CT scan, were compared to 43 controls without VTE, matching cases to controls by age, gender, BMI, hip diagnosis, clinical predisposing factors, and VTE prophylaxis. Five of 42 cases (12%) and 0/43 controls (0%) had Antithrombin III Deficiency (ATIII) (
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heritable thrombophilia and development of thromboembolic disease after total hip arthroplasty the treatment of osteoarthritis of the hip 1920
Clinical Orthopaedics and Related Research, 2005Co-Authors: Eduardo A Salvati, Alejandro Gonzalez Della Valle, Geoffrey H Westrich, Adam J Rana, Lawrence M Specht, Babette B Weksler, Ping Wang, Charles J GlueckAbstract:We retrospectively assessed whether heritable thrombophilia-hypofibrinolysis was more common in patients developing venous thromboembolism after total hip replacement than among control patients who did not develop venous thromboembolism, as an approach to better identify causes of venous thromboembolism after total hip arthroplasty. Twenty patients with proximal deep venous thrombosis after THA and 23 patients with symptomatic pulmonary embolism were compared with 43 control patients who did not have postoperative venous thromboembolism. Five of 42 patients with venous thromboembolism (12%) and 0 of 43 control patients (0%) had Antithrombin III Deficiency (< 75%). Nine of 42 patients with venous thromboembolism (21%) and 2 of 43 control patients (4.7%) had protein C Deficiency (< 70%). Ten of 43 patients with venous thromboembolism (9 heterozygous, 1 homozygous; 23%) and 1 of 43 control patients (heterozygous; 2%) had the prothrombin gene mutation. Patients who had venous thromboembolism after total hip arthroplasty were more likely than matched control pa tients to have heritable thrombophilia with Antithrombin III or protein C Deficiency, or homo-heterozygosity for the prothrombin gene mutation. Screening for these three tests of heritable thrombophilia before total hip arthroplasty should improve the identification of patients with a reduced risk of venous thromboembolism who may need only mild thromboprophylaxis, and of those patients with heritable thrombophilia in whom prophylaxis should be more aggressive.
Vasantha Muthu Muthuppalaniappan - One of the best experts on this subject based on the ideXlab platform.
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bilateral renal artery thrombosis in inherited thrombophilia a rare cause of acute kidney injury
International Journal of Nephrology and Renovascular Disease, 2014Co-Authors: Kate Wiles, Laura Hastings, Vasantha Muthu Muthuppalaniappan, Muhammad Hanif, Sumith AbeygunasekaraAbstract:We describe the case of a 47-year-old man who developed significant acute, and subsequently chronic, kidney injury due to bilateral renal infarction. This occurred in the context of a combined inherited thrombophilia including Antithrombin III Deficiency and a prothrombin gene mutation. Bilateral renal artery thrombosis developed despite prophylactic treatment for thromboembolism. Arterial thrombosis is rare in the context of inherited thrombophilia and bilateral renal infarction is an unusual cause of acute kidney injury. Bilateral renal infarction due to primary renal artery thrombosis has not been previously described in Antithrombin III Deficiency, either as an isolated defect or in combination with other hereditary thrombophilia.
Laura Hastings - One of the best experts on this subject based on the ideXlab platform.
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bilateral renal artery thrombosis in inherited thrombophilia a rare cause of acute kidney injury
International Journal of Nephrology and Renovascular Disease, 2014Co-Authors: Kate Wiles, Laura Hastings, Vasantha Muthu Muthuppalaniappan, Muhammad Hanif, Sumith AbeygunasekaraAbstract:We describe the case of a 47-year-old man who developed significant acute, and subsequently chronic, kidney injury due to bilateral renal infarction. This occurred in the context of a combined inherited thrombophilia including Antithrombin III Deficiency and a prothrombin gene mutation. Bilateral renal artery thrombosis developed despite prophylactic treatment for thromboembolism. Arterial thrombosis is rare in the context of inherited thrombophilia and bilateral renal infarction is an unusual cause of acute kidney injury. Bilateral renal infarction due to primary renal artery thrombosis has not been previously described in Antithrombin III Deficiency, either as an isolated defect or in combination with other hereditary thrombophilia.