The Experts below are selected from a list of 879 Experts worldwide ranked by ideXlab platform
Hisakazu Hoshi - One of the best experts on this subject based on the ideXlab platform.
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Superficial Inguinal Lymph Node Dissection
Operative Dictations in General and Vascular Surgery, 2017Co-Authors: T. J. Henry, Hisakazu HoshiAbstract:Superficial inguinal lymph node dissection (inguinofemoral lymphadenectomy) is performed when there is involvement of inguinal nodes from regional malignancies (e.g., melanoma, squamous Carcinoma of the Anus, Carcinoma of the vulva, scrotum, penis, or distal urethra). This chapter lists the indications, essential steps, common technical variations, and complications of the procedure. A detailed template operative dictation note is included.
Michael Bonebrake - One of the best experts on this subject based on the ideXlab platform.
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Superficial Inguinal Lymph Node Dissection
Operative Dictations in General and Vascular Surgery, 2011Co-Authors: Michael BonebrakeAbstract:Clinical involvement of inguinal nodes from: melanoma, squamous Carcinoma of the Anus, Carcinoma of the vulva, scrotum, penis, or distal urethra. Positive sentinel lymph node biopsy, in the absence of distant metastasis. Palliative dissection for control of symptomatic nodal disease.
T. J. Henry - One of the best experts on this subject based on the ideXlab platform.
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Superficial Inguinal Lymph Node Dissection
Operative Dictations in General and Vascular Surgery, 2017Co-Authors: T. J. Henry, Hisakazu HoshiAbstract:Superficial inguinal lymph node dissection (inguinofemoral lymphadenectomy) is performed when there is involvement of inguinal nodes from regional malignancies (e.g., melanoma, squamous Carcinoma of the Anus, Carcinoma of the vulva, scrotum, penis, or distal urethra). This chapter lists the indications, essential steps, common technical variations, and complications of the procedure. A detailed template operative dictation note is included.
Gong Jian-jun - One of the best experts on this subject based on the ideXlab platform.
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Prevention and conduct of compliments in patients with lower rectal Carcinoma undergoing operations of retention of Anus
Journal of Xinjiang Medical University, 2007Co-Authors: Gong Jian-junAbstract:Objectives: To explore the relative problems of excision of low rectal Carcinoma and retention of Anus. Methods: We retrospectively reviewed 47 patients with rectal Carcinoma to analysis the results of operational treatment. Among the 47 patients, 10 were performed with Mile′s procedures, 37 were dealed with Dixson′s procedures, while the others were dealed with local excision (6 transsacral Carcinoma removal, 4 per Anus Carcinoma removal). In 18 operations, a single anastomat was used. A double anastomat was used in 9 operations. Results: No case was dead in the patients investigated. Complication happened in or after operation includes; 4 homorrage of presacral venous plexus, 5 anastomotic leakage (1 was dealed with a colostomy; 4 were cured by dressing change), 17 disruption of wound, 1 instinctnal termination necrosis (dealed with Miles method). Conclusion: For patient with low rectal Carcinoma,we should choose optimal operational method to retain Anus and its function as possible as we can. According to factual situation, such as position, size, tumorous characteristic, pathological grading, local infiltration, and the operationer′s experiences, to attain the extension of life and improvement of quality of life.
Ensheng Zhao - One of the best experts on this subject based on the ideXlab platform.
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The prognostic value of HPV combined p16 status in patients with anal squamous cell Carcinoma: a meta-analysis.
Oncotarget, 2017Co-Authors: Guorui Sun, Xiaoyuan Dong, Xiaolong Tang, Hao Zhang, Ensheng ZhaoAbstract:// Guorui Sun 1 , Xiaoyuan Dong 2 , Xiaolong Tang 1 , Hui Qu 1 , Hao Zhang 1 and Ensheng Zhao 1 1 Department of Gastrointestinal Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China 2 Department of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China Correspondence to: Xiaoyuan Dong, email: dongxiaoyuan01@126.com Keywords: HPV; p16; Anus Carcinoma; prognosis; meta-analysis Received: July 19, 2017 Accepted: December 15, 2017 Published: December 21, 2017 ABSTRACT Human papillomavirus (HPV) DNA and p16 expression have been identified to be related to the progression of anal squamous cell Carcinoma (ASCC). However, the prognostic relevance of combined detection, particularly HPV-/p16+ and HPV+/p16- signatures, is unknown. A meta-analysis of epidemiologic studies was therefore conducted to address this issue. Data were collected from studies comparing overall survival (OS) and disease-free survival (DFS) / disease-specific survival (DSS) / relapse-free survival (RFS) / progression-free survival (PFS) in ASCC patients with HPV and p16 status. The electronic databases of MEDLINE and EMBASE were searched from their inception till 31 May 2017. Study-specific risk estimates were pooled using a fixed-effects model for OS and DFS/DSS/RFS/PFS. Four studies involving a total of 398 ASCC cases were included in this meta-analysis. The pooled results showed that HPV+/p16+ cancers were significantly associated with improved OS (HR = 0.30, 95% CI: 0.17–0.51) and DFS/DSS/RFS/PFS (HR = 0.23, 95% CI: 0.14–0.36). However, patients with HPV-/p16+ or HPV+/p16- do not have a comparably good prognosis compared with HPV+/p16+ patients. The meta-analysis indicated that concomitant detection of HPV-DNA and p16 expression may be of prognostic or therapeutic utility in the evaluation of factors contributing to ASCC. Testing tumor specimens for HPV-DNA and p16 expression might indirectly affect treatment decisions.
