The Experts below are selected from a list of 102 Experts worldwide ranked by ideXlab platform
Yasufumi Sawada - One of the best experts on this subject based on the ideXlab platform.
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Nightmares and Panic Disorder Associated with Carvedilol Overdose
Annals of Pharmacotherapy, 2002Co-Authors: Chiharu Maebara, Hisakazu Ohtani, Hideyo Sugahara, Kazunori Mine, Chiharu Kubo, Yasufumi SawadaAbstract:OBJECTIVE:To report a case of nightmares and sleep disorder associated with improper use of carvedilol, an α/β-blocker, and to model the time course of receptor occupancy in this patient.CASE SUMMARY:A 41-year-old man with panic disorder had been treated with alprazolam 1.2 mg/d (3 × daily), carvedilol 10 mg/d (once in the morning), and etizolam 0.5 mg (for Anxiety Attack). Although the physical and psychological symptoms gradually improved, he reported nightmares and panic Attacks. An interview revealed that he had been taking carvedilol 5 mg twice a day after lunch and dinner on his own initiative, in addition to the prescribed dosage. The patient was asked to take carvedilol 10 mg only after breakfast, as had been advised. Consequently, the sleep disorder and nightmares disappeared.METHODS:We calculated the time courses of β2-adrenoceptor binding occupancy in the central nervous system after oral administration of carvedilol with the ordinary and improper regimens by using pharmacokinetic/pharmacodynam...
Chiharu Maebara - One of the best experts on this subject based on the ideXlab platform.
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Nightmares and Panic Disorder Associated with Carvedilol Overdose
Annals of Pharmacotherapy, 2002Co-Authors: Chiharu Maebara, Hisakazu Ohtani, Hideyo Sugahara, Kazunori Mine, Chiharu Kubo, Yasufumi SawadaAbstract:OBJECTIVE:To report a case of nightmares and sleep disorder associated with improper use of carvedilol, an α/β-blocker, and to model the time course of receptor occupancy in this patient.CASE SUMMARY:A 41-year-old man with panic disorder had been treated with alprazolam 1.2 mg/d (3 × daily), carvedilol 10 mg/d (once in the morning), and etizolam 0.5 mg (for Anxiety Attack). Although the physical and psychological symptoms gradually improved, he reported nightmares and panic Attacks. An interview revealed that he had been taking carvedilol 5 mg twice a day after lunch and dinner on his own initiative, in addition to the prescribed dosage. The patient was asked to take carvedilol 10 mg only after breakfast, as had been advised. Consequently, the sleep disorder and nightmares disappeared.METHODS:We calculated the time courses of β2-adrenoceptor binding occupancy in the central nervous system after oral administration of carvedilol with the ordinary and improper regimens by using pharmacokinetic/pharmacodynam...
Sarah Zelner - One of the best experts on this subject based on the ideXlab platform.
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housing instability and health findings from the michigan recession and recovery study
Social Science & Medicine, 2012Co-Authors: Sarah A Burgard, Kristin S Seefeldt, Sarah ZelnerAbstract:The recession of the late 2000s has increased interest in the consequences of housing instability. Previous research has shown poorer health among those experiencing housing instability, but extant studies generally have focused on selected populations (e.g., homeowners or renters) or studied only one type of housing instability (e.g. homelessness). Using new data from the Michigan Recession and Recovery Study, a population-based sample of working-aged adults from Southeastern Michigan, U.S.A., in late 2009–early 2010, we found that about one-third of respondents recently experienced some type of housing instability. Many, but not all, types of instability were associated with health. Even after adjustment for sociodemographic characteristics and earlier health, individuals who had moved for cost reasons in the past three years were more likely than those with no housing instability to report a recent Anxiety Attack, while those who experienced homelessness in the past year had a higher likelihood of reporting fair/poor self-rated health and of meeting criteria for major or minor depression. Renters behind on rental payments were more likely to meet criteria for depression, while mortgage-holders behind on their mortgage or in foreclosure had a higher likelihood of reporting fair/poor self-rated health or a recent Anxiety Attack. Among respondents who had ever owned a home, those who completed a foreclosure recently were more likely to report major or minor depression or an Anxiety Attack. However, frequent moves were not associated with poorer health, and doubling up and eviction were not associated with poorer health after adjustment for characteristics that sort people into different housing instability experiences. Our findings suggest the importance of considering multiple types of housing instability and using appropriate risk groups and comparison categories.
Chiharu Kubo - One of the best experts on this subject based on the ideXlab platform.
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Nightmares and Panic Disorder Associated with Carvedilol Overdose
Annals of Pharmacotherapy, 2002Co-Authors: Chiharu Maebara, Hisakazu Ohtani, Hideyo Sugahara, Kazunori Mine, Chiharu Kubo, Yasufumi SawadaAbstract:OBJECTIVE:To report a case of nightmares and sleep disorder associated with improper use of carvedilol, an α/β-blocker, and to model the time course of receptor occupancy in this patient.CASE SUMMARY:A 41-year-old man with panic disorder had been treated with alprazolam 1.2 mg/d (3 × daily), carvedilol 10 mg/d (once in the morning), and etizolam 0.5 mg (for Anxiety Attack). Although the physical and psychological symptoms gradually improved, he reported nightmares and panic Attacks. An interview revealed that he had been taking carvedilol 5 mg twice a day after lunch and dinner on his own initiative, in addition to the prescribed dosage. The patient was asked to take carvedilol 10 mg only after breakfast, as had been advised. Consequently, the sleep disorder and nightmares disappeared.METHODS:We calculated the time courses of β2-adrenoceptor binding occupancy in the central nervous system after oral administration of carvedilol with the ordinary and improper regimens by using pharmacokinetic/pharmacodynam...
Kazunori Mine - One of the best experts on this subject based on the ideXlab platform.
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Nightmares and Panic Disorder Associated with Carvedilol Overdose
Annals of Pharmacotherapy, 2002Co-Authors: Chiharu Maebara, Hisakazu Ohtani, Hideyo Sugahara, Kazunori Mine, Chiharu Kubo, Yasufumi SawadaAbstract:OBJECTIVE:To report a case of nightmares and sleep disorder associated with improper use of carvedilol, an α/β-blocker, and to model the time course of receptor occupancy in this patient.CASE SUMMARY:A 41-year-old man with panic disorder had been treated with alprazolam 1.2 mg/d (3 × daily), carvedilol 10 mg/d (once in the morning), and etizolam 0.5 mg (for Anxiety Attack). Although the physical and psychological symptoms gradually improved, he reported nightmares and panic Attacks. An interview revealed that he had been taking carvedilol 5 mg twice a day after lunch and dinner on his own initiative, in addition to the prescribed dosage. The patient was asked to take carvedilol 10 mg only after breakfast, as had been advised. Consequently, the sleep disorder and nightmares disappeared.METHODS:We calculated the time courses of β2-adrenoceptor binding occupancy in the central nervous system after oral administration of carvedilol with the ordinary and improper regimens by using pharmacokinetic/pharmacodynam...