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Apocrine Sweat Gland

The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform

H Keles – 1st expert on this subject based on the ideXlab platform

  • histopathological and immunohistochemical studies of Apocrine Sweat Gland adenocarcinomas in cats
    Veterinary and Comparative Oncology, 2014
    Co-Authors: R Haziroglu, M Haligur, H Keles

    Abstract:

    : Seven adenocarcinomas of Apocrine Sweat Glands among the 67 cutaneous tumours of cats were evaluated between 1980 and 2005. Histopathologically, three tumours were solid, tubular, tubular-ductal, tubular-cystic and papillar-cystic types were also diagnosed each one. Cuboidal and squamous epithelial cells surrounding the cystic lumina and their papillar extensions into the cyst lumens were evident in almost all tumour types. Besides, fibrovascular stroma which surrounding neoplastic foci showed proliferation and stromal invasion. Immunohistochemical features of these tumours were examined with pan-cytokeratin, vimentin and carcinoembryonic antigen.

Yoshiro Ebihara – 2nd expert on this subject based on the ideXlab platform

  • two cases of Apocrine Sweat Gland carcinoma of axilla
    The Journal of the Japanese Society of Clinical Cytology, 2002
    Co-Authors: Masako Otani, Yoshiro Ebihara, Hiromi Serizawa, Tohru Shimizu, Koh Nakazawa, Kayoko Higuchi

    Abstract:

    背景:皮膚原発のアポクリン癌はまれで, さまざまな抗体を用いることにより組織学的診断が可能であるが, 細胞所見の報告は少ない.われわれは腋窩部原発アポクリン癌の2例を経験し, その細胞学的特徴を検討した.症例:症例1は49歳男性で5年前に左腋窩部腫瘍摘出術を受けたが, 局所再発をきたした.吸引細胞診ではほとんどが孤立散在性で, 一部に上皮性細胞集塊が含まれていた.腫瘍細胞は細胞質が厚くて広く, 断頭分泌を認めた.組織学的には充実性, 索状および腺管状構造を示し, 腫瘍細胞の細胞質は広く好酸性で, 断頭分泌, ジアスターゼ抵抗性PAS陽性顆粒が認められた.GCDFP-15が陽性であった.症例2は53歳の男性で, 15年前に左腋窩部腫瘤の診断を受け, 摘出術が施行された.リンパ節の擦過細胞診では比較的重積性の少ない上皮性細胞集塊が主体で, 腫瘍細胞は大型で広い細胞質, 円形から卵円形の偏在核と明瞭な核小体を持ち, 断頭分泌が認められた.組織学的には潰瘍を形成し, 腺管形成を伴い皮下脂肪織まで浸潤していた.細胞質は広く好酸性で断頭分泌が認められ, ジアスターゼ抵抗性PAS陽性顆粒を含んでいた.GCDFP-15が陽性であった.結論:腋窩部に発生するアポクリン癌は汗腺あるいは副乳由来のアポクリン癌や転移性腺癌が鑑別となる.皮膚原発アポクリン癌は細胞診でも特徴的な像を保持しており, 詳細な検討によって推定診断が可能であると考えられた.

  • cytologic features of pleural effusion in Apocrine Sweat Gland carcinoma a case report
    Acta Cytologica, 2001
    Co-Authors: Masako Otani, Yoko Maeda, Yoko Miyake, Myota Miura, Motoshige Kudo, Yoshiro Ebihara

    Abstract:

    BACKGROUND: Carcinoma arising in the Apocrine Sweat Glands is very rare, and there are few reports of the cytologic features. We encountered a case of metastatic Apocrine carcinoma in a pleural effusion. CASE: A 46-year-old male had a dark reddish nodule in the right axillary region that was diagnosed as Apocrine carcinoma of skin appendage origin. Three years after wide resection and chemotherapy, widespread metastases developed with a massive pleural effusion. Needle aspiration fluid cytology contained clusters of adenocarcinoma. Some tumor cells had abundant cytoplasm or periodic acid‐Schiff-positive, coarse granules. Decapitation secretion was occasionally found on the cell surface. Immunohistochemically, the tumor cells were often positive for BRST-2 and BRST-3. CONCLUSION: Cytologic features of metastatic Apocrine Sweat Gland carinoma show some characteristics of adenocarcinoma. Moreover, its definitive diagnosis in a pleural effusion can be made because of retaining the characteristics of Apocrine Sweat Gland. (Acta Cytol 2001;45:74‐78)

  • a case of Apocrine Sweat Gland carcinoma cytologic features of the metastatic lesion
    The Journal of the Japanese Society of Clinical Cytology, 1999
    Co-Authors: Masako Otani, Toru Shimizu, Hiromi Serizawa, Yoshie Wakatsuki, Yoshiro Ebihara

    Abstract:

    An 83-year-old male was diagnosed with Apocrine Sweat Gland carcinoma in the right axillary region. After the first operation, a metastatic lesion near the primary site was noticed and a second operation was performed. Cytological examination showed tumor clusters arranged in papillary or sheet-like pattern. Some of the tumor cells had abundant eosinophilic cytoplasm with Orange G-stained coarse granules and were positive for GCDFP-15 and B 72.3 immunohistochemically.In conclusion, cytological features of the metastatic lesion retain the characteristic cytological appearance of Apocrine Sweat Glands, which enabled a diagnosis of carcinoma of Apocrine Sweat Gland origin.

R Haziroglu – 3rd expert on this subject based on the ideXlab platform

  • histopathological and immunohistochemical studies of Apocrine Sweat Gland adenocarcinomas in cats
    Veterinary and Comparative Oncology, 2014
    Co-Authors: R Haziroglu, M Haligur, H Keles

    Abstract:

    : Seven adenocarcinomas of Apocrine Sweat Glands among the 67 cutaneous tumours of cats were evaluated between 1980 and 2005. Histopathologically, three tumours were solid, tubular, tubular-ductal, tubular-cystic and papillar-cystic types were also diagnosed each one. Cuboidal and squamous epithelial cells surrounding the cystic lumina and their papillar extensions into the cyst lumens were evident in almost all tumour types. Besides, fibrovascular stroma which surrounding neoplastic foci showed proliferation and stromal invasion. Immunohistochemical features of these tumours were examined with pan-cytokeratin, vimentin and carcinoembryonic antigen.