The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
R. P. Dellinger - One of the best experts on this subject based on the ideXlab platform.
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Continuous Intra-Arterial Blood Gas Monitoring
Critical care medicine, 1995Co-Authors: R. P. Dellinger, J. L. ZimmermanAbstract:Arterial Blood gas analysis is necessary for the optimal management and treatment of many critically ill patients. Currently, Arterial Blood gases (ABG) are measured intermittently. Continuous measurement of PO2, PCO2, and pH in Arterial Blood would be a major medical advance for the intensivist. Certain patient populations in the intensive care unit (ICU) would clearly benefit from continuous intra-Arterial Blood gas monitoring (CIABGM). CIABGM would not be expected to totally replace intermittent ABG sampling and periodic calibration of a CIABGM device may also be necessary.
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Initial evaluation of a new intra-Arterial Blood gas system in humans.
Critical care medicine, 1993Co-Authors: J. L. Zimmerman, R. P. DellingerAbstract:OBJECTIVE To evaluate the in vivo performance of a continuous intra-Arterial Blood gas monitor as compared with in vitro Arterial Blood gases for measurements of PaO2, PaCO2, and Arterial pH. DESIGN Consecutive patient enrollment. SETTING Medical intensive care unit of a county teaching hospital. PATIENTS Five critically ill patients. INTERVENTIONS All patients had a fiberoptic sensor placed through a 20-gauge cannula inserted into the radial artery. Sensor and Arterial Blood gas measurements were monitored up to 68 hrs. Arterial Blood gases were analyzed on two Blood gas analyzers. MEASUREMENTS AND MAIN RESULTS A total of 104 Arterial Blood gases were obtained for comparison of sensor measurements with Blood gas analyzer values. Comparison of the sensor values with the Blood gas analyzer values showed bias and precision values of -0.021 and 0.037 for Arterial pH, 1.74 and 6.06 torr (0.23 and 0.81 kPa) for PaCO2, and -5.89 and 13.19 torr (-0.79 and 1.76 kPa) for PaO2, respectively. Comparison of the two Blood gas analyzer measurements showed bias and precision values of -0.030 and 0.010 for Arterial pH, 1.96 and 2.55 torr (0.26 and 0.34 kPa) for PaCO2, and -5.77 and 17.15 torr (-0.77 and 2.29 kPa) for PaO2, respectively. No complications attributable to the sensor were detected. CONCLUSIONS The performance of this fiberoptic continuous intra-Arterial Blood gas monitor is comparable to that of Blood gas analyzers and compares favorably with previously reported studies utilizing other sensors in reliably and reproducibly approximating PaO2, PaCO2, and Arterial pH values. This monitoring capability was accomplished with no patient morbidity. Further study is indicated to confirm these initial results and to establish the role of a continuous intra-Arterial Blood gas monitor in critically ill patients.
J. L. Zimmerman - One of the best experts on this subject based on the ideXlab platform.
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Continuous Intra-Arterial Blood Gas Monitoring
Critical care medicine, 1995Co-Authors: R. P. Dellinger, J. L. ZimmermanAbstract:Arterial Blood gas analysis is necessary for the optimal management and treatment of many critically ill patients. Currently, Arterial Blood gases (ABG) are measured intermittently. Continuous measurement of PO2, PCO2, and pH in Arterial Blood would be a major medical advance for the intensivist. Certain patient populations in the intensive care unit (ICU) would clearly benefit from continuous intra-Arterial Blood gas monitoring (CIABGM). CIABGM would not be expected to totally replace intermittent ABG sampling and periodic calibration of a CIABGM device may also be necessary.
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Initial evaluation of a new intra-Arterial Blood gas system in humans.
Critical care medicine, 1993Co-Authors: J. L. Zimmerman, R. P. DellingerAbstract:OBJECTIVE To evaluate the in vivo performance of a continuous intra-Arterial Blood gas monitor as compared with in vitro Arterial Blood gases for measurements of PaO2, PaCO2, and Arterial pH. DESIGN Consecutive patient enrollment. SETTING Medical intensive care unit of a county teaching hospital. PATIENTS Five critically ill patients. INTERVENTIONS All patients had a fiberoptic sensor placed through a 20-gauge cannula inserted into the radial artery. Sensor and Arterial Blood gas measurements were monitored up to 68 hrs. Arterial Blood gases were analyzed on two Blood gas analyzers. MEASUREMENTS AND MAIN RESULTS A total of 104 Arterial Blood gases were obtained for comparison of sensor measurements with Blood gas analyzer values. Comparison of the sensor values with the Blood gas analyzer values showed bias and precision values of -0.021 and 0.037 for Arterial pH, 1.74 and 6.06 torr (0.23 and 0.81 kPa) for PaCO2, and -5.89 and 13.19 torr (-0.79 and 1.76 kPa) for PaO2, respectively. Comparison of the two Blood gas analyzer measurements showed bias and precision values of -0.030 and 0.010 for Arterial pH, 1.96 and 2.55 torr (0.26 and 0.34 kPa) for PaCO2, and -5.77 and 17.15 torr (-0.77 and 2.29 kPa) for PaO2, respectively. No complications attributable to the sensor were detected. CONCLUSIONS The performance of this fiberoptic continuous intra-Arterial Blood gas monitor is comparable to that of Blood gas analyzers and compares favorably with previously reported studies utilizing other sensors in reliably and reproducibly approximating PaO2, PaCO2, and Arterial pH values. This monitoring capability was accomplished with no patient morbidity. Further study is indicated to confirm these initial results and to establish the role of a continuous intra-Arterial Blood gas monitor in critically ill patients.
K J Falke - One of the best experts on this subject based on the ideXlab platform.
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Preliminary evaluation of a new continuous intra-Arterial Blood gas monitoring device.
Acta anaesthesiologica Scandinavica. Supplementum, 1995Co-Authors: D Pappert, R Rossaint, K Lewandowski, R Kuhlen, H Gerlach, K J FalkeAbstract:Continuous intra-Arterial Blood gas monitoring is a new technique, possibly offering therapeutic advantages through improved monitoring in patients prone to hypoxaemia, hypercapnia and/or respiratory acidosis. Therefore, we studied the clinical applicability, reliability, precision and side effect of long-term continuous intra-Arterial Blood gas monitoring in patients suffering from severe acute respiratory distress syndrome. In 10 patients continuous intra-Arterial Blood gas monitoring based on fluorescent optodes technique was performed. At 4 h intervals, Arterial Blood samples for in vitro Blood gas analyses were drawn, stored in ice, and analysed within 3 min. Evaluation of data retrieved from the continuous intra-Arterial Blood gas monitoring and in vitro Blood gas analysis was based on 596 data points using 10 catheters. Average length of insertion was 281 +/- 215 h, max. lengths of stay was 750 h. Arterial Blood gas data obtained in vivo were compared to the mean of in vivo and in vitro Arterial Blood gases. Inter-catheter bias, expressed as percent difference between continuous intra-Arterial Blood gas and mean in vitro Blood gas analysis was 0.19 +/- 0.23% for pH. 1.1 +/- 5.2% for PaCO2 and 1.6 +/- 5.7% for PaO2. No significant gas partial pressure dependent change in precision was demonstrable. There was no significant time dependent drift in sensor precision over the study period. No negative side-effects related to IABG monitoring were observed. We conclude that long-term use of this new device is possible in patients and represents a reliable alternative to conventional in vitro Arterial Blood gas analysis, when continuous monitoring of Blood gases and/or acid-base balance is critical.
Marianne Thoresen - One of the best experts on this subject based on the ideXlab platform.
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respiratory sinus arrhythmia stabilizes mean Arterial Blood pressure at high frequency interval in healthy humans
European Journal of Applied Physiology, 2015Co-Authors: Maja Elstad, Lars Walloe, Nathalie Linn Holme, Elke Maes, Marianne ThoresenAbstract:Purpose Arterial Blood pressure variations are an independent risk factor for end organ failure. Respiratory sinus arrhythmia (RSA) is a sign of a healthy cardiovascular system. However, whether RSA counteracts Arterial Blood pressure variations during the respiratory cycle remains controversial. We restricted normal RSA with non-invasive intermittent positive pressure ventilation (IPPV) to test the hypothesis that RSA normally functions to stabilize mean Arterial Blood pressure.
M K Schmid - One of the best experts on this subject based on the ideXlab platform.
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Evaluation of a continuous non-invasive Arterial Blood pressure monitoring device in comparison with an Arterial Blood pressure measurement in the ICU
Critical Care, 2011Co-Authors: K Smolle, M K SchmidAbstract:Due to a lower risk of complications, non-invasive monitoring methods gain importance. Measuring Arterial Blood pressure belongs to the standard hemodynamic monitoring. A newly developed continuous non-invasive Arterial Blood pressure (CNAP) measurement method is available and has been validated perioperatively [1]. We compared the CNAP monitoring device with invasive Arterial Blood pressure measurement (IBP) as the gold standard in critically ill patients.
