The Experts below are selected from a list of 114 Experts worldwide ranked by ideXlab platform
A C Hall - One of the best experts on this subject based on the ideXlab platform.
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Orthopaedic Proceedings, 2018Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown.A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used.The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue wit...
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Journal of Bone and Joint Surgery-british Volume, 2015Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown. A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used. The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue with 24% cell death at moderate pressure compared to a control (p=0.0699). The widely assumed benign Arthroscopic Probe produces significant cell death in articular cartilage when used at standard operating pressures.
E K Davidson - One of the best experts on this subject based on the ideXlab platform.
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Orthopaedic Proceedings, 2018Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown.A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used.The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue wit...
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Journal of Bone and Joint Surgery-british Volume, 2015Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown. A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used. The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue with 24% cell death at moderate pressure compared to a control (p=0.0699). The widely assumed benign Arthroscopic Probe produces significant cell death in articular cartilage when used at standard operating pressures.
T O White - One of the best experts on this subject based on the ideXlab platform.
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Orthopaedic Proceedings, 2018Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown.A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used.The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue wit...
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how benign is the Arthroscopic Probe a laboratory based study using bovine and human joints
Journal of Bone and Joint Surgery-british Volume, 2015Co-Authors: E K Davidson, T O White, A C HallAbstract:Articular cartilage has very poor repair potential, however it has an extraordinary capacity to withstand physiological mechanical loads in an intact joint. The nature and extent of chondrocyte death in articular cartilage following many forms of injury (trephine, scalpel, osteotome, sutures and drilling) has been characterised, but the ability to bear mechanical injury from iatrogenic surgical interventions is still unknown. A standard Arthroscopic Probe was moved at varying physiological pressures along the articular cartilage of joint before staining with fluorescent dyes to allow live/dead cell imaging using laser confocal scanning microscopy and imaging software, Image J. Bovine metatarsal phalangeal joints and fresh human cadaveric femoral condyles were used. The Probe caused statistically significant chondrocyte death in bovine cartilage (p=0.02). Mild pressure 5% cell death, moderate (standard Arthroscopic technique pressure) 22% and severe pressure 38%. A similar result was seen in human tissue with 24% cell death at moderate pressure compared to a control (p=0.0699). The widely assumed benign Arthroscopic Probe produces significant cell death in articular cartilage when used at standard operating pressures.
Jonathan Rasio - One of the best experts on this subject based on the ideXlab platform.
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Patients with a Hypoplastic Labrum Achieve Similar Outcomes After Primary Labral Repair in the Treatment of Femoracetablular Impingement Syndrome Compared to Patients with a Normal Labrum
Orthopaedic Journal of Sports Medicine, 2020Co-Authors: Justin Drager, Alexander Newhouse, Jorge Chahla, Jonathan RasioAbstract:Objectives: A preoperative or intraoperative finding of an acetabular labrum width of <4mm is often cited as an indication for performing primary labral reconstruction over repair in the surgical correction of Femoracetablular Impingement Syndrome (FAIS). The purpose of this study is to compare patient reported clinical outcomes and rates of reaching Minimum Clinical Important Differences (MCID) and Patient Acceptable Symptomatic State (PASS) between patients with a hypoplastic labrum compared to those with a normal labrum width at a minimum 1 year from Arthroscopic treatment of FAIS. Methods: Data from consecutive patients who underwent primary hip arthroscopy between November 2015 and July 2018 for the treatment of FAIS were analyzed. Baseline demographic data, preoperative, and minimum 1 year post-operative clinical outcomes including Hip Outcome Score-Activities of Daily Living (HOS-ADL), HOS-Sports Subscale (HOS-SS), modified Harris Hip Score (mHHS), international Hip Outcome Tool 12 questions (iHOT-12), and visual analog scale (VAS) for pain and satisfaction were recorded. The labrum size was documented by the senior surgeon for all patients using the tip of an Arthroscopic Probe measuring 4mm. Labrum hypoplasia was defined as a labrum width at the 12 o’clock position of <4mm and normal labrum was defined as labrum width between 4 and 7mm. Patients with hypoplastic labrum were matched 1:1 by age and BMI to patients with normal labrum width. All patients underwent Arthroscopic labral repair in addition to impingement resection and capsular repair. The groups were further compared after separating by acetabular coverage, in which a Lateral Center Edge Angle of 18-24.9 was considered borderline dysplastic and 25-40 was considered normal. Rates of achieving MCID calculated using a distribution-based method and PASS calculated using an anchor-based method. Results: A total of 360 patients were included in the study with 180 in each of the normal and hypoplastic groups. There was no significant differences seen in 1-year post operative outcome scores or score improvement between the two groups. When examining only borderline dysplastic patients there were no significant differences in outcomes between normal and hypoplastic labrum patients. In the subset with a normal LCEA only post-operative VAS satisfaction (85.5 ± 19.3 vs 78.2 ± 27.4; p=0.050) was significantly higher in the normal labrum patients compared to hypoplastic labrum. Patients with hypoplastic labrum achieved MCID and PASS at the same rate as patients with normal labrum across all outcome measures. Conclusions: Patients with an intraoperative finding of labral hypoplasia achieve 1-year meaningful clinical outcome at the same rate as those with normal labral width following Arthroscopic labral repair. These results bring into question the need for primary labral reconstruction in patients with labral hypoplasia with a normal or borderline dysplastic acetabulum.
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Patients With a Hypotrophic Labrum Achieve Similar Outcomes After Primary Labral Repair Compared With Patients With a Normal-Sized Labrum: A Matched Cohort Analysis of 346 Patients With Femoroacetabular Impingement Syndrome
Arthroscopy, 2020Co-Authors: Justin Drager, Jonathan Rasio, Alexander Newhouse, Edward C. Beck, Jorge ChahlaAbstract:Purpose To compare patient functional scores and rates of achieving minimum clinically important differences (MCID) and patient acceptable symptomatic state (PASS) between patients with a hypotrophic labrum with those with a normal labrum width at a minimum 1-year follow-up from Arthroscopic treatment of femoroacetabular impingement syndrome. Methods Data from consecutive patients who underwent primary hip arthroscopy between November 2015 and July 2018 for the treatment of femoroacetabular impingement syndrome were analyzed. Baseline demographic data, preoperative patient-reported outcome measures (PROMs), and minimum 1-year PROMs, including Hip Outcome Score-Activities of Daily Living, Hip Outcome Score-Sports Subscale, modified Harris Hip Score, international Hip Outcome Tool 12 questions, and visual analog scale for pain and satisfaction were recorded. The labrum size was determined using an Arthroscopic Probe at the 12- to 2-o’clock position with a hypotrophic labrum being defined as Results A total of 346 patients were included in the study with an average age of 31.4 ± 11.9 and a majority being female (72.0%). There were 173 in each of the normal and hypotrophic groups. There were no significant differences seen in 1-year PROMs between the 2 groups (P > .05 for all). The normal labrum group achieved MCID at a rate of 75% to 84% and PASS at a rate of 51% to 70%. The hypotrophic labrum group achieved MCID at a rate of 70% to 85% and PASS at a rate of 57% to 71%. There were no significant differences in rates between each group (P > .05 for all). Conclusions Patients with an intraoperative finding of labral hypotrophy achieve 1-year meaningful clinical outcome at the same rate as those with normal labral width following Arthroscopic labral repair. Level of Evidence III, Case–control study
Jorge Chahla - One of the best experts on this subject based on the ideXlab platform.
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Patients with a Hypoplastic Labrum Achieve Similar Outcomes After Primary Labral Repair in the Treatment of Femoracetablular Impingement Syndrome Compared to Patients with a Normal Labrum
Orthopaedic Journal of Sports Medicine, 2020Co-Authors: Justin Drager, Alexander Newhouse, Jorge Chahla, Jonathan RasioAbstract:Objectives: A preoperative or intraoperative finding of an acetabular labrum width of <4mm is often cited as an indication for performing primary labral reconstruction over repair in the surgical correction of Femoracetablular Impingement Syndrome (FAIS). The purpose of this study is to compare patient reported clinical outcomes and rates of reaching Minimum Clinical Important Differences (MCID) and Patient Acceptable Symptomatic State (PASS) between patients with a hypoplastic labrum compared to those with a normal labrum width at a minimum 1 year from Arthroscopic treatment of FAIS. Methods: Data from consecutive patients who underwent primary hip arthroscopy between November 2015 and July 2018 for the treatment of FAIS were analyzed. Baseline demographic data, preoperative, and minimum 1 year post-operative clinical outcomes including Hip Outcome Score-Activities of Daily Living (HOS-ADL), HOS-Sports Subscale (HOS-SS), modified Harris Hip Score (mHHS), international Hip Outcome Tool 12 questions (iHOT-12), and visual analog scale (VAS) for pain and satisfaction were recorded. The labrum size was documented by the senior surgeon for all patients using the tip of an Arthroscopic Probe measuring 4mm. Labrum hypoplasia was defined as a labrum width at the 12 o’clock position of <4mm and normal labrum was defined as labrum width between 4 and 7mm. Patients with hypoplastic labrum were matched 1:1 by age and BMI to patients with normal labrum width. All patients underwent Arthroscopic labral repair in addition to impingement resection and capsular repair. The groups were further compared after separating by acetabular coverage, in which a Lateral Center Edge Angle of 18-24.9 was considered borderline dysplastic and 25-40 was considered normal. Rates of achieving MCID calculated using a distribution-based method and PASS calculated using an anchor-based method. Results: A total of 360 patients were included in the study with 180 in each of the normal and hypoplastic groups. There was no significant differences seen in 1-year post operative outcome scores or score improvement between the two groups. When examining only borderline dysplastic patients there were no significant differences in outcomes between normal and hypoplastic labrum patients. In the subset with a normal LCEA only post-operative VAS satisfaction (85.5 ± 19.3 vs 78.2 ± 27.4; p=0.050) was significantly higher in the normal labrum patients compared to hypoplastic labrum. Patients with hypoplastic labrum achieved MCID and PASS at the same rate as patients with normal labrum across all outcome measures. Conclusions: Patients with an intraoperative finding of labral hypoplasia achieve 1-year meaningful clinical outcome at the same rate as those with normal labral width following Arthroscopic labral repair. These results bring into question the need for primary labral reconstruction in patients with labral hypoplasia with a normal or borderline dysplastic acetabulum.
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Patients With a Hypotrophic Labrum Achieve Similar Outcomes After Primary Labral Repair Compared With Patients With a Normal-Sized Labrum: A Matched Cohort Analysis of 346 Patients With Femoroacetabular Impingement Syndrome
Arthroscopy, 2020Co-Authors: Justin Drager, Jonathan Rasio, Alexander Newhouse, Edward C. Beck, Jorge ChahlaAbstract:Purpose To compare patient functional scores and rates of achieving minimum clinically important differences (MCID) and patient acceptable symptomatic state (PASS) between patients with a hypotrophic labrum with those with a normal labrum width at a minimum 1-year follow-up from Arthroscopic treatment of femoroacetabular impingement syndrome. Methods Data from consecutive patients who underwent primary hip arthroscopy between November 2015 and July 2018 for the treatment of femoroacetabular impingement syndrome were analyzed. Baseline demographic data, preoperative patient-reported outcome measures (PROMs), and minimum 1-year PROMs, including Hip Outcome Score-Activities of Daily Living, Hip Outcome Score-Sports Subscale, modified Harris Hip Score, international Hip Outcome Tool 12 questions, and visual analog scale for pain and satisfaction were recorded. The labrum size was determined using an Arthroscopic Probe at the 12- to 2-o’clock position with a hypotrophic labrum being defined as Results A total of 346 patients were included in the study with an average age of 31.4 ± 11.9 and a majority being female (72.0%). There were 173 in each of the normal and hypotrophic groups. There were no significant differences seen in 1-year PROMs between the 2 groups (P > .05 for all). The normal labrum group achieved MCID at a rate of 75% to 84% and PASS at a rate of 51% to 70%. The hypotrophic labrum group achieved MCID at a rate of 70% to 85% and PASS at a rate of 57% to 71%. There were no significant differences in rates between each group (P > .05 for all). Conclusions Patients with an intraoperative finding of labral hypotrophy achieve 1-year meaningful clinical outcome at the same rate as those with normal labral width following Arthroscopic labral repair. Level of Evidence III, Case–control study
