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Mohamed Eddouks - One of the best experts on this subject based on the ideXlab platform.
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potent antihyperglycemic and hypoglycemic effect of tamarix Articulata vahl in normal and streptozotocin induced diabetic rats
Biomedicine & Pharmacotherapy, 2017Co-Authors: Morad Hebi, Omra Farid, Mohammed Ajebli, Mohamed EddouksAbstract:The purpose of this study was to investigate the effect of a single dose and daily oral administration for seven days of the aerial part aqueous extract (A.P.A.E) of Tamarix Articulata Vahl. (T. Articulata) (5mg/kg) on blood glucose levels in both normal and streptozotocin-induced diabetic rats (STZ). Single oral administration of T. Articulata A.P.A.E reduced blood glucose levels 6h after administration in normal rats (p<0.0001) and STZ diabetic rats (p<0.001). Furthermore, blood glucose levels were decreased in both normal (p<0.05) and STZ diabetic rats (p<0.0001) after seven days of treatment. Moreover, no significant changes in body weight in normal and STZ rats were shown. According to the oral glucose tolerance test, the aqueous extract of T. Articulata (5mg/kg) was shown to prevent significantly the increase on blood glucose levels in both normal and diabetic treated rats 30min, 60min and 120min after glucose administration when compared to the control group. Additionally, histopathological analysis revealed the beneficial effect of T. Articulata on pancreas and liver. Finally, the antioxydant activity of the aqueous extract of Tamarix Articulata was evaluated by the method of trapping of free radical 2,2-diphenyl-1 picrylhydrazyl (DPPH). Tamarix Articulata revealed inhibitory concentrations of 50% of free radicals (IC50) of 203.15μg/ml. In contrast, the synthetic antioxidant butylhydroxytoluene (BHT) has showed an IC50 equal to 13.71μg/ml. In conclusion, this study demonstrates antihyperglycemic, hypoglycemic and antioxidant effects of T. Articulata in severe diabetic state thus warrants further investigation on its major compounds as well as mechanistic studies.
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Potent antihyperglycemic and hypoglycemic effect of Tamarix Articulata Vahl. in normal and streptozotocin-induced diabetic rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017Co-Authors: Morad Hebi, Omra Farid, Mohammed Ajebli, Mohamed EddouksAbstract:The purpose of this study was to investigate the effect of a single dose and daily oral administration for seven days of the aerial part aqueous extract (A.P.A.E) of Tamarix Articulata Vahl. (T. Articulata) (5mg/kg) on blood glucose levels in both normal and streptozotocin-induced diabetic rats (STZ). Single oral administration of T. Articulata A.P.A.E reduced blood glucose levels 6h after administration in normal rats (p
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Hypolipidemic activity of Tamarix Articulata Vahl. in diabetic rats.
Journal of integrative medicine, 2017Co-Authors: Morad Hebi, Mohamed EddouksAbstract:Abstract Objective Tamarix Articulata Vahl. (Tamaricaceae) is a medicinal plant commonly used in Morocco for the treatment of diabetes mellitus and cardiovascular diseases. The objective of this study was to evaluate the hypolipidemic activity of aqueous extract of T. Articulata in normal and streptozotocin (STZ)-induced diabetic rats. Phytochemical analysis as well as determination of polyphenol and flavonoid contents in the aqueous extract of T. Articulata was performed. Methods The effects of oral administration of aqueous extract of T. Articulata (5 mg/kg) on the plasma total cholesterol, triglyceride and high-density lipoprotein cholesterol (HDL-c) concentrations were measured in both normal and STZ-induced diabetic rats. Total phenolic content of the aqueous extract was determined by Folin-Ciocalteu method. In addition, determination of flavonoid content was performed using colorimetric AlCl 3 method. Results A single oral administration in diabetic rats induced a significant increase in the HDL-c concentration after 6 h of treatment with T. Articulata (5 mg/kg). The results also demonstrated that the aqueous extract of T. Articulata produced a significant decrease of serum total cholesterol after repeated oral administration in diabetic rats ( P T. Articulata aqueous extract were equal to 102.50 mg of gallic acid equivalent per gram of extract and 54.83 mg of quercetin equivalent per gram of extract, respectively. Conclusion According to preliminary phytochemical screening of the aerial part of T. Articulata , several classes of chemicals have been found, such as polyphenols, flavonoids, tannins, cyanidins (flavones, catechols), mucilage, sesquiterpenes, terpenoids and carbohydrates. In conclusion, T. Articulata exhibits a hypolipidemic effect in diabetic rats and its beneficial role as hypolipidemic agent should be evaluated in clinical studies.
Morad Hebi - One of the best experts on this subject based on the ideXlab platform.
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potent antihyperglycemic and hypoglycemic effect of tamarix Articulata vahl in normal and streptozotocin induced diabetic rats
Biomedicine & Pharmacotherapy, 2017Co-Authors: Morad Hebi, Omra Farid, Mohammed Ajebli, Mohamed EddouksAbstract:The purpose of this study was to investigate the effect of a single dose and daily oral administration for seven days of the aerial part aqueous extract (A.P.A.E) of Tamarix Articulata Vahl. (T. Articulata) (5mg/kg) on blood glucose levels in both normal and streptozotocin-induced diabetic rats (STZ). Single oral administration of T. Articulata A.P.A.E reduced blood glucose levels 6h after administration in normal rats (p<0.0001) and STZ diabetic rats (p<0.001). Furthermore, blood glucose levels were decreased in both normal (p<0.05) and STZ diabetic rats (p<0.0001) after seven days of treatment. Moreover, no significant changes in body weight in normal and STZ rats were shown. According to the oral glucose tolerance test, the aqueous extract of T. Articulata (5mg/kg) was shown to prevent significantly the increase on blood glucose levels in both normal and diabetic treated rats 30min, 60min and 120min after glucose administration when compared to the control group. Additionally, histopathological analysis revealed the beneficial effect of T. Articulata on pancreas and liver. Finally, the antioxydant activity of the aqueous extract of Tamarix Articulata was evaluated by the method of trapping of free radical 2,2-diphenyl-1 picrylhydrazyl (DPPH). Tamarix Articulata revealed inhibitory concentrations of 50% of free radicals (IC50) of 203.15μg/ml. In contrast, the synthetic antioxidant butylhydroxytoluene (BHT) has showed an IC50 equal to 13.71μg/ml. In conclusion, this study demonstrates antihyperglycemic, hypoglycemic and antioxidant effects of T. Articulata in severe diabetic state thus warrants further investigation on its major compounds as well as mechanistic studies.
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Potent antihyperglycemic and hypoglycemic effect of Tamarix Articulata Vahl. in normal and streptozotocin-induced diabetic rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017Co-Authors: Morad Hebi, Omra Farid, Mohammed Ajebli, Mohamed EddouksAbstract:The purpose of this study was to investigate the effect of a single dose and daily oral administration for seven days of the aerial part aqueous extract (A.P.A.E) of Tamarix Articulata Vahl. (T. Articulata) (5mg/kg) on blood glucose levels in both normal and streptozotocin-induced diabetic rats (STZ). Single oral administration of T. Articulata A.P.A.E reduced blood glucose levels 6h after administration in normal rats (p
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Hypolipidemic activity of Tamarix Articulata Vahl. in diabetic rats.
Journal of integrative medicine, 2017Co-Authors: Morad Hebi, Mohamed EddouksAbstract:Abstract Objective Tamarix Articulata Vahl. (Tamaricaceae) is a medicinal plant commonly used in Morocco for the treatment of diabetes mellitus and cardiovascular diseases. The objective of this study was to evaluate the hypolipidemic activity of aqueous extract of T. Articulata in normal and streptozotocin (STZ)-induced diabetic rats. Phytochemical analysis as well as determination of polyphenol and flavonoid contents in the aqueous extract of T. Articulata was performed. Methods The effects of oral administration of aqueous extract of T. Articulata (5 mg/kg) on the plasma total cholesterol, triglyceride and high-density lipoprotein cholesterol (HDL-c) concentrations were measured in both normal and STZ-induced diabetic rats. Total phenolic content of the aqueous extract was determined by Folin-Ciocalteu method. In addition, determination of flavonoid content was performed using colorimetric AlCl 3 method. Results A single oral administration in diabetic rats induced a significant increase in the HDL-c concentration after 6 h of treatment with T. Articulata (5 mg/kg). The results also demonstrated that the aqueous extract of T. Articulata produced a significant decrease of serum total cholesterol after repeated oral administration in diabetic rats ( P T. Articulata aqueous extract were equal to 102.50 mg of gallic acid equivalent per gram of extract and 54.83 mg of quercetin equivalent per gram of extract, respectively. Conclusion According to preliminary phytochemical screening of the aerial part of T. Articulata , several classes of chemicals have been found, such as polyphenols, flavonoids, tannins, cyanidins (flavones, catechols), mucilage, sesquiterpenes, terpenoids and carbohydrates. In conclusion, T. Articulata exhibits a hypolipidemic effect in diabetic rats and its beneficial role as hypolipidemic agent should be evaluated in clinical studies.
Claus Nielsen - One of the best experts on this subject based on the ideXlab platform.
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Proposing a solution to the Articulata–Ecdysozoa controversy
Zoologica Scripta, 2003Co-Authors: Claus NielsenAbstract:475Nielsen, C. (2003) Proposing a solution to the Articulata −Ecdysozoa controversy. — ZoologicaScripta, 32, 475–482.Recent studies of animal radiation agree on monophyly of the Bilateria, but there is noconsensus about the early radiation of the group. Protostomia and Deuterostomia are usuallyrecognized, with two competing theories regarding the division of the Protostomia: onedivides them into Spiralia and Cycloneuralia, the other into Lophotrochozoa and Ecdysozoa.The main discrepancy concerns the Arthropoda, which are placed with the Articulata withinthe Spiralia by the first group, and with the Cycloneuralia within the Ecdysozoa by the second.Here I propose that this discrepancy can be resolved by regarding the Ecdysozoa as the sistergroup of the Annelida within the Articulata. This implies that segmentation has been lost inphyla such as Nematoda and Priapula, but the Kinorhyncha may show a ‘reduced segmenta-tion’ with serially arranged muscles associated with a ringed cuticle. Morphological, palaeon-tological and molecular implications of this theory are discussed. While many morphologicaland palaeontological data can be interpreted in accordance with the theory, the molecular dataremain inconclusive.Claus Nielsen, Zoological Museum (University of Copenhagen), Universitetsparken 15, DK-2100Copenhagen, Denmark. E-mail: cnielsen@zmuc.ku.dk
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proposing a solution to the Articulata ecdysozoa controversy
Zoologica Scripta, 2003Co-Authors: Claus NielsenAbstract:475Nielsen, C. (2003) Proposing a solution to the Articulata −Ecdysozoa controversy. — ZoologicaScripta, 32, 475–482.Recent studies of animal radiation agree on monophyly of the Bilateria, but there is noconsensus about the early radiation of the group. Protostomia and Deuterostomia are usuallyrecognized, with two competing theories regarding the division of the Protostomia: onedivides them into Spiralia and Cycloneuralia, the other into Lophotrochozoa and Ecdysozoa.The main discrepancy concerns the Arthropoda, which are placed with the Articulata withinthe Spiralia by the first group, and with the Cycloneuralia within the Ecdysozoa by the second.Here I propose that this discrepancy can be resolved by regarding the Ecdysozoa as the sistergroup of the Annelida within the Articulata. This implies that segmentation has been lost inphyla such as Nematoda and Priapula, but the Kinorhyncha may show a ‘reduced segmenta-tion’ with serially arranged muscles associated with a ringed cuticle. Morphological, palaeon-tological and molecular implications of this theory are discussed. While many morphologicaland palaeontological data can be interpreted in accordance with the theory, the molecular dataremain inconclusive.Claus Nielsen, Zoological Museum (University of Copenhagen), Universitetsparken 15, DK-2100Copenhagen, Denmark. E-mail: cnielsen@zmuc.ku.dk
Robin Duponnois - One of the best experts on this subject based on the ideXlab platform.
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Growth and nutrition of Tetraclinis Articulata (Vahl) Mast. cultivated in different rhizosphere soils collected from Tetraclinis stand
Biotechnologie Agronomie Société et Environnement, 2013Co-Authors: Younes Abbas, Salah Eddine Bakkali Yakhlef, Y. Prin, Mohamed Abourouh, Moustapha Arahou, Robin DuponnoisAbstract:Croissance et nutrition du thuya de Berberie (Tetraclinis Articulata [Vahl] Mast.) mis en culture dans differents sols rhizospheriques de peuplement de thuya. Cinq especes vegetales (Withania frutescens Pauquy, Lavandula multifida L., Pistacia atlantica Desf., Olea europaea L. subsp. oleaster (Hoffmanns. & Link) Negodi et Tetraclinis Articulata [Vahl] Mast.), rencontrees au niveau de l’ecosysteme tetraclinaie au Maroc ont ete selectionnees afin d'evaluer leur potentiel mycorhizien et de comparer l’impact de leur sol rhizospherique sur la croissance et la nutrition des jeunes plants de thuya (Tetraclinis Articulata). Les racines des plantes selectionnees ont ete abondamment colonisees par les champignons mycorhiziens arbusculaires (AM). Les racines de L. multifida ont montre le pourcentage le plus eleve de mycorhization (100 %). Nous avons ensuite isole les spores de champignons AM a partir du sol de ces cinq especes de plantes et nous avons constate que le nombre total de spores isolees de la rhizosphere de L. multifida et T. Articulata a ete sensiblement different de celui des autres plantes. Le potentiel mycorhizien des sols indigenes a ete evalue en utilisant l’approche du nombre le plus probable (MPN). Nous avons constate que ce nombre etait significativement plus eleve dans les sols recoltes pres des cinq especes de plantes, que celui dans le sol sans couvert vegetal, soit une moyenne du MPN par 100 g de sol sec de 11,8 (compris entre 5,6 et 25,0) dans le sol nu et 228,5 (compris entre 108,0 et 476,0) dans la rhizosphere de L. multifida. Ce resultat indique que le sol entourant les plantes cibles peut etre utilise comme inoculum mycorhizien. En pepiniere forestiere, les plants de thuya mis en culture dans le sol sous la lavande ont montre les meilleurs pourcentages de mycorhization et ont pu ameliorer leur croissance. Toutefois, la production en arbuscules du thuya se developpant dans la rhizosphere de la lavande n'a pas significativement affecte la croissance ou la nutrition des plants par rapport a ceux se developpant dans un sol sous le thuya, sauf pour la concentration du potassium. Nos recherches ont montre clairement que le sol sous L. multifida peut etre utilise comme inoculum mycorhizien efficace dans la production de T. Articulata en pepinieres forestieres, et peut participer ainsi au maintien de l’ecosysteme tetraclinaie.
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Effective arbuscular mycorrhizal fungi in the roots of Tetraclinis Articulata and Lavandula multifida in Moroccan Tetraclinis woodlands
Mycology, 2011Co-Authors: Salah Eddine Bakkali Yakhlef, Younes Abbas, Y. Prin, Mohamed Abourouh, Marie-mathilde Perrineau, Robin DuponnoisAbstract:The diversity of arbuscular mycorrhizal fungi (AMF) in roots of two plant species (arar, Tetraclinis Articulata and lavender, Lavandula multifida) that exist alone or co-occur in Moroccan Tetraclinis woodlands was characterized using molecular techniques. The interaction between the two plant species on their root AMF communities was also studied. We analysed the large subunit (LSU) ribosomal RNA gene amplified by nested PCR from a root DNA extract using AM fungal-specific primers. A total of 200 cloned fragments from five root bulk samples of the two plant species were analysed by restriction fragment length polymorphism (RFLP) and 30 of them were sequenced. Phylogenetic analyses demonstrated that these RFLP types correspond to eight phylotypes: five belonged to the Gigasporaceae and three to the Glomeraceae. The highest diversity was found in the roots of T. Articulata alone, followed by the association T. Articulata/L. multifida and, finally, L. multifida alone. Many AMF were shared between the two spe...
Jonas Veenhoven - One of the best experts on this subject based on the ideXlab platform.
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quality control of natural resins used in historical european lacquer reconstructions with some reflections on the composition of sandarac resin tetraclinis Articulata vahl mast
Journal of Analytical and Applied Pyrolysis, 2021Co-Authors: Louise Decq, Piet Stoffelen, Vincent Cattersel, Joy Mazurek, Wim Fremout, Jonas Veenhoven, Frederic LynenAbstract:Abstract In order to verify correct labeling and purity of natural lacquer ingredients sold today, 66 resins, gums and oils were analyzed by THM-GC/MS and compared with non-commercial reference samples. 21 deviations were found, indicating an adulteration or mislabeling of a resin. Many of the deviations occurred in sandarac resin, traditionally harvested from Tetraclinis Articulata (Vahl) Mast., which seems to have another composition today than historically. Differences between both types were persistent through artificial aging. This study comprised one freshly harvested sandarac resin, as well as several specimens of historical collections, as reference material for Tetraclinis Articulata. The currently sold sandarac was compared with the Tetraclinis Articulata references, and with resins from the genera Agathis, Juniperus and Callitris, but its botanical source was not revealed.
