Aspiration Catheter

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Heng Zhang - One of the best experts on this subject based on the ideXlab platform.

Lu Yunlan - One of the best experts on this subject based on the ideXlab platform.

  • e0419 The applying of Aspiration Catheter in revascularisation in patients with ST-elevation myocardial infarction
    Heart, 2010
    Co-Authors: Li Weiming, Xu Yawei, Chen Yangqing, Wei Yidong, Li Yuanmin, Che Wenliang, Hou Lei, Lu Yunlan
    Abstract:

    Objectives To observe the immediate and recent treatment effects of applying the Aspiration Catheter in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Methods From March to June 2010, we enrolled the STEMI patients presenting with TIMI Flow Grade 0 or 1 in the infarct related artery (IRA) at baseline CAG undergoing primary PCI. The Aspiration Catheter (Medtronic Inc., Export?) was applied immediately to aspirate the intracoronary thrombus. Whether predilatating and/or stenting were decided by the blood flow and the condition of lesions. The patients from October 2009 to February 2010 who was diagnosed as STEMI and received non-Aspiration were enrolled as control group. The immediate and recent clinical outcomes of applying the Aspiration Catheter were compared between the two groups. Results There were 25 cases in Group thrombus-Aspiration (2 cases of subacute stent thrombosis). After having aspirated the intracoronary thrombus using the Aspiration Catheter, 14 cases of STEMI recovered immediately (9 cases received direct stenting; 3 cases implanted stents after balloon predilatation, and had satisfied results; 2 cases of subacute stent thrombosis received the antithrombotic therapy, included intravenous infusion of Xinweining for 36 h in CCU immediately after recovering TIMI grade-3 flow). 10 cases recovered TIMI 1-2, 1 cases also showed no-reflow. All of the 11 cases received the balloon predilatation and stenting, only one showed slow flow, the others recovered. There was no other severe complication during and after the operation. There was no in-stent thrombosis during 1 month follow-up, and the cardiac function improved largely. There were 22 cases in Group non-Aspiration, 4 cases received direct stenting, 18 cases received balloon predilatation and stenting.5 cases showed slow flow, 3 cases recovered normal flow after intra-coronary infusion of nitroglycerin, verapamil and Xinweinin, but 2 cases also showed TIMI 1, and accompanied heart failure. Conclusions The applying of Aspiration Catheter in patients with STEMI prior to primary PCI could increase the opportunities of direct stenting, improve myocardial reperfusion, immediate and recent clinical outcomes as compared with PCI in the absence of thrombus Aspiration, and also show ease and safe procedure.

Jeanpierre Pruvo - One of the best experts on this subject based on the ideXlab platform.

  • endovascular stroke therapy with a novel 6 french Aspiration Catheter
    CardioVascular and Interventional Radiology, 2019
    Co-Authors: M Bretzner, Laurent Estrade, Marc Ferrigno, Fouzi Bala, F Boustia, Apolline Kazemi, Jeanpierre Pruvo
    Abstract:

    Direct thrombus Aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel Aspiration Catheter available: the 6-French AXS Catalyst Catheter. We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed. Among the 60 patients included, 30 were treated using Aspiration alone, 14 were treated using Aspiration and then stent retriever as a rescue therapy, and 16 were treated using Aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%. Endovascular stroke therapy using the AXS Catalyst Catheter seems safe and effective, with similar performance than other reperfusion Catheters.

  • Endovascular Stroke Therapy with a Novel 6-French Aspiration Catheter.
    Cardiovascular and interventional radiology, 2018
    Co-Authors: M Bretzner, Laurent Estrade, Marc Ferrigno, Fouzi Bala, F Boustia, Apolline Kazemi, Jeanpierre Pruvo, Hilde Hénon, Nicolas Bricout
    Abstract:

    BACKGROUND AND PURPOSE Direct thrombus Aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel Aspiration Catheter available: the 6-French AXS Catalyst Catheter. MATERIALS AND METHODS We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed. RESULTS Among the 60 patients included, 30 were treated using Aspiration alone, 14 were treated using Aspiration and then stent retriever as a rescue therapy, and 16 were treated using Aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%. CONCLUSION Endovascular stroke therapy using the AXS Catalyst Catheter seems safe and effective, with similar performance than other reperfusion Catheters.

Nobutaka Horie - One of the best experts on this subject based on the ideXlab platform.

  • Impact of Mechanical Thrombectomy Device on Thrombus Histology in Acute Embolic Stroke.
    World Neurosurgery, 2019
    Co-Authors: Nobutaka Horie, Yuki Matsunaga, Yoichi Morofuji, Kazuya Shobayashi, Eisaku Sadakata, Yusuke Iki, Tadashi Kanamoto, Yohei Tateishi, Tsuyoshi Izumo, Takeo Anda
    Abstract:

    Background Although many studies have evaluated the retrieved thrombus to assess the cause of stroke after mechanical thrombectomy for acute large vessel occlusion, the results remain controversial. We investigated the hypothesis that histology of the retrieved thrombus is enhanced by mechanical thrombectomy devices. Methods Thrombi were collected from consecutive patients who had undergone endovascular mechanical recanalization for large intracranial vessel occlusion. The mechanical thrombectomy device used was either an Aspiration Catheter or a stent retriever. The hematoxylin and eosin–stained specimens were quantitatively analyzed with respect to the relative fractions of the main constituents (erythrocytes and fibrin). Clinical and radiologic findings were also evaluated. Results Of 65 patients, an Aspiration Catheter was used in 27, and a stent retriever was used in 38. The presence of a preoperative susceptibility vessel sign on magnetic resonance imaging was not correlated with the percentage of erythrocytes. Thrombus cross-sectional area was larger in the Aspiration group than in the stent group (P Conclusions Histologic differences in retrieved thrombi are enhanced by mechanical thrombectomy devices. Stent retrievers may crush the thrombus, which may have a synergistic effect with recombinant tissue plasminogen activator. Histology of the retrieved thrombi might be different from histology of the original thrombi.

  • Abstract TP27: Impact of Mechanical Thrombectomy Device on the Thrombus Histology in Acute Embolic Stroke
    Stroke, 2017
    Co-Authors: Nobutaka Horie, Yoichi Morofuji, Eisaku Sadakata, Yohei Tateishi, Tsuyoshi Izumo, Minoru Morikawa, Akira Tsujino, Takayuki Matsuo
    Abstract:

    Background and Purpose: Thrombus composition has been suggested to have a decisive impact on the outcome of patients treated by mechanical thrombectomy because of embolic stroke. The aim of this prospective study was to assess the impact of a mechanical thrombectomy device (Penumbra Aspiration Catheter vs. Stent retriever) on thrombus composition, which could affect flow impairment after reperfusion. Methods: Thrombi of consecutive stroke patients with large vessel occlusion were collected during intracranial mechanical recanalization. Mechanical thrombectomy device was used either Penumbra Aspiration Catheter or Stent retriever. The hematoxylin and eosin-stained specimens were quantitatively analyzed in terms of the relative fractions of the main constituents (red blood cells and fibrin/platelets). Results: Of 65 cardio-embolic patients, Penumbra Aspiration Catheter was used in 27 patients, and Stent retriever was used in 38 patients. There was no significance in age, sex, occlusion vessel, NIH stroke scale, and onset to reperfusion time. The volume of thrombi was significantly larger in Penumbra group compared with that in Stent group (3.68 cm3 vs. 0.95 cm3, P Conclusions: Stent retriever could crush thrombus and reduce its size, which induce distal migration of the red blood cell component. However, it did not affect the final infarct lesion and outcome.

Hong-ju Wang - One of the best experts on this subject based on the ideXlab platform.

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