The Experts below are selected from a list of 3156 Experts worldwide ranked by ideXlab platform

Muneyasu Saito - One of the best experts on this subject based on the ideXlab platform.

Vidya S. Banka - One of the best experts on this subject based on the ideXlab platform.

  • Asynergy in Coronary Heart Disease
    Annals of Internal Medicine, 2020
    Co-Authors: Richard H. Helfant, Monty M. Bodenheimer, Vidya S. Banka
    Abstract:

    Abstract The widespread use of cardiac ventriculography has focused interest on the frequency with which Asynergy accompanies coronary heart disease as well as on its clinical and prognostic implic...

  • Relationship Between Regional Myocardial Perfusion and the Presence, Severity and Reversibility of Asynergy in Patients with Coronary Heart Disease
    2016
    Co-Authors: Monty M. Bodenheimer, Vidya S. Banka, Colleen Fooshee, George A. Hermann, H. Helfant
    Abstract:

    SUMMARY In this study, the interrelationship of regional myocardial perfusion at rest and after exercise, the presence, severity and reversibility of Asynergy and the severity of the corresponding coronary arterial obstruction was examined. Forty-five patients underwent exercise testing with thallium-201, cardiac cathe-terization including intervention (nitroglycerin) ventriculography and coronary arteriography. Of the 45 pa-tients, 13 were normal by catheterization while 32 had coronary heart disease (CHD). Of the 32 with CHD, 21 had Asynergy and 11 had normal ventricular contraction. Eighteen of 21 patients with Asynergy also had a myocardial perfusion abnormality after exercise, while only three of the 11 without Asynergy had a perfu-sion abnormality (P < 0.001). Of the 21 hypokinetic zones, only 67 % had a myocardial perfusion abnormal-ity, while all of the akinetic and dyskinetic zones had a perfusion defect (P < 0.025). Twenty-seven left ventricular zones demonstrated perfusion abnormalities after exercise, of which 19 had either normal or improved myocardial perfusion at rest. Fifteen of these 19 had reversible Asynergy on nitroglycerin ventriculography while three had normal contraction. In contrast, the eight zones with myo-cardial perfusion defects, both at rest and with exercise, all had associated Asynergy which was irreversible. A significant relationship was also observed between the severity of the coronary arterial obstruction, asyn-ergy and a perfusion abnormality. Thus, of 39 myocardial zones supplied by 2 90 % coronary arterial lesions

Takanori Yasu - One of the best experts on this subject based on the ideXlab platform.

Monty M. Bodenheimer - One of the best experts on this subject based on the ideXlab platform.

  • Asynergy in Coronary Heart Disease
    Annals of Internal Medicine, 2020
    Co-Authors: Richard H. Helfant, Monty M. Bodenheimer, Vidya S. Banka
    Abstract:

    Abstract The widespread use of cardiac ventriculography has focused interest on the frequency with which Asynergy accompanies coronary heart disease as well as on its clinical and prognostic implic...

  • Relationship Between Regional Myocardial Perfusion and the Presence, Severity and Reversibility of Asynergy in Patients with Coronary Heart Disease
    2016
    Co-Authors: Monty M. Bodenheimer, Vidya S. Banka, Colleen Fooshee, George A. Hermann, H. Helfant
    Abstract:

    SUMMARY In this study, the interrelationship of regional myocardial perfusion at rest and after exercise, the presence, severity and reversibility of Asynergy and the severity of the corresponding coronary arterial obstruction was examined. Forty-five patients underwent exercise testing with thallium-201, cardiac cathe-terization including intervention (nitroglycerin) ventriculography and coronary arteriography. Of the 45 pa-tients, 13 were normal by catheterization while 32 had coronary heart disease (CHD). Of the 32 with CHD, 21 had Asynergy and 11 had normal ventricular contraction. Eighteen of 21 patients with Asynergy also had a myocardial perfusion abnormality after exercise, while only three of the 11 without Asynergy had a perfu-sion abnormality (P < 0.001). Of the 21 hypokinetic zones, only 67 % had a myocardial perfusion abnormal-ity, while all of the akinetic and dyskinetic zones had a perfusion defect (P < 0.025). Twenty-seven left ventricular zones demonstrated perfusion abnormalities after exercise, of which 19 had either normal or improved myocardial perfusion at rest. Fifteen of these 19 had reversible Asynergy on nitroglycerin ventriculography while three had normal contraction. In contrast, the eight zones with myo-cardial perfusion defects, both at rest and with exercise, all had associated Asynergy which was irreversible. A significant relationship was also observed between the severity of the coronary arterial obstruction, asyn-ergy and a perfusion abnormality. Thus, of 39 myocardial zones supplied by 2 90 % coronary arterial lesions

  • Differential Effect in the Presence of Reversible and Irreversible Asynergy
    2015
    Co-Authors: Rajnikant Shah, Monty M. Bodenheimer, Vidyc S. Banka, Richard H. Helfant
    Abstract:

    The effect of nitroglygerin administration on left ventricular performance relative to its ability to improve confraclion of asynergic zones was examined in 66 patients with coronary artery disease, divided into those whose asynergic zones responded following nitroglycerin adminisfration and those in whom no response was observed, In the responsive group with Asynergy of more than one segment, the ejection fraction improved (P < 0.001), while in the unresponsive group, it decreased (P < 0.05). Similarly, in patients with one-segment Asynergy, the responsive group exhibited a significant increase in ejection fracII ecent studies in our laboratory,14 as well as in others,49 have indicated that nitroglycerin administration can effectively distinguish zones of Asynergy with and without residual contractile ability. These studies have also shown that the presence of pathologic Q waves and the severity of coronary obstruction adversely affect the potential for zonal reversibility, while the presence of collateral vessels increases the likelihood of reversibiity;’#{176}� however, the effect of nitroglycerin administration on the reversibility of Asynergy as it affects global ventricular performance is incompletely understood. The present study was undertaken to examine the effect of nitroglycerin administration on left ventricular performance in the presence of reversible or irreversible Asynergy.

Abhijeet Dhoble - One of the best experts on this subject based on the ideXlab platform.