The Experts below are selected from a list of 12 Experts worldwide ranked by ideXlab platform
Ok-joon Kim - One of the best experts on this subject based on the ideXlab platform.
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Journal of Pharmacology, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala , a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology : 6 min 27 sec Full Screen Alternate
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Pharmacological Society, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala, a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology: 6 min 27 sec Full Screen Alternat
Ni Kou - One of the best experts on this subject based on the ideXlab platform.
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Journal of Pharmacology, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala , a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology : 6 min 27 sec Full Screen Alternate
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Pharmacological Society, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala, a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology: 6 min 27 sec Full Screen Alternat
Hyejoung Cho - One of the best experts on this subject based on the ideXlab platform.
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Journal of Pharmacology, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala , a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology : 6 min 27 sec Full Screen Alternate
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Pharmacological Society, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala, a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology: 6 min 27 sec Full Screen Alternat
Hye-eun Kim - One of the best experts on this subject based on the ideXlab platform.
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Journal of Pharmacology, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala , a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology : 6 min 27 sec Full Screen Alternate
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Pharmacological Society, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala, a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology: 6 min 27 sec Full Screen Alternat
Qiaochu Sun - One of the best experts on this subject based on the ideXlab platform.
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Journal of Pharmacology, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala , a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology : 6 min 27 sec Full Screen Alternate
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Anti-cancer effect of Atractylodes Macrocephala Extract by double induction of apoptotic and autophagic cell death in head and neck cancer cells
Bangladesh Pharmacological Society, 2017Co-Authors: Ni Kou, Hyejoung Cho, Hye-eun Kim, Qiaochu Sun, Kyuhyeon Ahn, Hongran Choi, Ok-joon KimAbstract:The apoptosis resistance restricts the efficacy of traditional therapies of head and neck squamous cell carcinoma (HNSCC). To overcome this problem, Atractylodes Macrocephala, a traditional Korean and Chinese herbal medicine, has been used in clinical practice. In the present study, the anticancer effect of A. Macrocephala Extract was investigated and its underlying mechanisms using head and neck cancer KB cell line. The Extract-induced cytotoxicity was mediated by autophagic cell death as well as apoptosis in HNSCC cells though extrinsic apoptotic pathway and the Akt/mTOR autophagic pathway. This study suggests that A. Macrocephala Extracts can be a potential drug to overcome side effects and susceptibility for head and neck carcinoma by double induction of apoptosis and autophagy. Video Clip of Methodology: 6 min 27 sec Full Screen Alternat
