Audio Frequencies

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The Experts below are selected from a list of 6483 Experts worldwide ranked by ideXlab platform

S Young - One of the best experts on this subject based on the ideXlab platform.

J Mcconnell - One of the best experts on this subject based on the ideXlab platform.

Ingo R. Titze - One of the best experts on this subject based on the ideXlab platform.

  • viscoelastic properties of three vocal fold injectable biomaterials at low Audio Frequencies
    2004
    Co-Authors: Sarah A. Klemuk, Ingo R. Titze
    Abstract:

    Objectives: Previous measurements of viscoelastic properties of Zyderm were to be extended to low Audio Frequencies, and properties of two other biomaterials not previously measured, thiolated hyaluronic acid (HA-DTPH) and Cymetra, were obtained. Study Design: Rheologic investigation. Methods: Oscillatory shear stress was applied to each sample using a controlled stress rheometer at Frequencies between 0.01 and 100 Hz with a parallel plate apparatus. Versuscoelastic moduli were recorded at each frequency. The calculated resonance frequency of the machine and sample were then used to determine the maximum frequency at which reliable data existed. Extrapolation functions were fit to viscoelastic parameters, which predicted the properties up to 1,000 Hz. Results: Frequency trends of Zyderm were similar to those previously reported, whereas magnitudes were different. The elastic moduli logarithmically increased with frequency, whereas dynamic viscosity demonstrated shear thinning, a condition of primary importance for humans to vocalize over a broad frequency range. Previous measurements were extended from 15 Hz up to 74 Hz. Differences in magnitude between a previous study and the present study were attributed to particulate orientation during testing. Cymetra was found to have nearly identical viscoelastic properties to those of bovine collagen, both in magnitude and frequency trend, with reliable measures extending up to 81 Hz. Rheologic properties of the hyaluronic acid gel were the closest match to cadaveric vocal fold mucosa in magnitude and frequency trend. Conclusions: Viscoelastic properties of Cymetra and Zyderm are nearly the same and are significantly greater than those of vocal fold mucosa. HA-DTPH possesses a good viscoelastic match to vocal fold mucosa and may be useful in future lamina propria repair.

  • Methodology for rheological testing of engineered biomaterials at low Audio Frequencies.
    2004
    Co-Authors: Ingo R. Titze, Sarah A. Klemuk, Steven D. Gray
    Abstract:

    A commercial rheometer (Bohlin CVO120) was used to mechanically test materials that approximate vocal-fold tissues. Application is to Frequencies in the low Audio range (20–150 Hz). Because commercial rheometers are not specifically designed for this frequency range, a primary problem is maintaining accuracy up to (and beyond) the mechanical resonance frequency of the rotating shaft assembly. A standard viscoelastic material (NIST SRM 2490) has been used to calibrate the rheometric system for an expanded frequency range. Mathematically predicted response curves are compared to measured response curves, and an error analysis is conducted to determine the accuracy to which the elastic modulus and the shear modulus can be determined in the 20–150-Hz region. Results indicate that the inertia of the rotating assembly and the gap between the plates need to be known (or determined empirically) to a high precision when the measurement frequency exceeds the resonant frequency. In addition, a phase correction is needed to account for the magnetic inertia (inductance) of the drag cup motor. Uncorrected, the measured phase can go below the theoretical limit of −π. This can produce large errors in the viscous modulus near and above the resonance frequency. With appropriate inertia and phase corrections, ±10% accuracy can be obtained up to twice the resonance frequency.

  • methodology for straining engineered vocal fold tissues at Audio Frequencies
    2001
    Co-Authors: Sarah A. Klemuk, Ingo R. Titze, Steven D. Gray
    Abstract:

    Engineered vocal fold tissues will be grown under conditions of shear strain, the magnitude of which is determined by known strains during human vocal fold oscillation. A cup and plate system is used with the Bohlin CVO 120 rheometer to apply a shear strain of approximately 0.4 radians at Frequencies of 20–60 Hz. Baseline viscoelastic measurements are recorded for the synthetic scaffolding material into which different cell lines will be injected and grown to form their own matrix. The methodology allows duration and repetitions of strain exposure to seeded scaffolding to be varied and for subsequent viscoelastic measurements to be compared. [Work supported by NIDCD.]

Sarah A. Klemuk - One of the best experts on this subject based on the ideXlab platform.

  • viscoelastic properties of three vocal fold injectable biomaterials at low Audio Frequencies
    2004
    Co-Authors: Sarah A. Klemuk, Ingo R. Titze
    Abstract:

    Objectives: Previous measurements of viscoelastic properties of Zyderm were to be extended to low Audio Frequencies, and properties of two other biomaterials not previously measured, thiolated hyaluronic acid (HA-DTPH) and Cymetra, were obtained. Study Design: Rheologic investigation. Methods: Oscillatory shear stress was applied to each sample using a controlled stress rheometer at Frequencies between 0.01 and 100 Hz with a parallel plate apparatus. Versuscoelastic moduli were recorded at each frequency. The calculated resonance frequency of the machine and sample were then used to determine the maximum frequency at which reliable data existed. Extrapolation functions were fit to viscoelastic parameters, which predicted the properties up to 1,000 Hz. Results: Frequency trends of Zyderm were similar to those previously reported, whereas magnitudes were different. The elastic moduli logarithmically increased with frequency, whereas dynamic viscosity demonstrated shear thinning, a condition of primary importance for humans to vocalize over a broad frequency range. Previous measurements were extended from 15 Hz up to 74 Hz. Differences in magnitude between a previous study and the present study were attributed to particulate orientation during testing. Cymetra was found to have nearly identical viscoelastic properties to those of bovine collagen, both in magnitude and frequency trend, with reliable measures extending up to 81 Hz. Rheologic properties of the hyaluronic acid gel were the closest match to cadaveric vocal fold mucosa in magnitude and frequency trend. Conclusions: Viscoelastic properties of Cymetra and Zyderm are nearly the same and are significantly greater than those of vocal fold mucosa. HA-DTPH possesses a good viscoelastic match to vocal fold mucosa and may be useful in future lamina propria repair.

  • Methodology for rheological testing of engineered biomaterials at low Audio Frequencies.
    2004
    Co-Authors: Ingo R. Titze, Sarah A. Klemuk, Steven D. Gray
    Abstract:

    A commercial rheometer (Bohlin CVO120) was used to mechanically test materials that approximate vocal-fold tissues. Application is to Frequencies in the low Audio range (20–150 Hz). Because commercial rheometers are not specifically designed for this frequency range, a primary problem is maintaining accuracy up to (and beyond) the mechanical resonance frequency of the rotating shaft assembly. A standard viscoelastic material (NIST SRM 2490) has been used to calibrate the rheometric system for an expanded frequency range. Mathematically predicted response curves are compared to measured response curves, and an error analysis is conducted to determine the accuracy to which the elastic modulus and the shear modulus can be determined in the 20–150-Hz region. Results indicate that the inertia of the rotating assembly and the gap between the plates need to be known (or determined empirically) to a high precision when the measurement frequency exceeds the resonant frequency. In addition, a phase correction is needed to account for the magnetic inertia (inductance) of the drag cup motor. Uncorrected, the measured phase can go below the theoretical limit of −π. This can produce large errors in the viscous modulus near and above the resonance frequency. With appropriate inertia and phase corrections, ±10% accuracy can be obtained up to twice the resonance frequency.

  • methodology for straining engineered vocal fold tissues at Audio Frequencies
    2001
    Co-Authors: Sarah A. Klemuk, Ingo R. Titze, Steven D. Gray
    Abstract:

    Engineered vocal fold tissues will be grown under conditions of shear strain, the magnitude of which is determined by known strains during human vocal fold oscillation. A cup and plate system is used with the Bohlin CVO 120 rheometer to apply a shear strain of approximately 0.4 radians at Frequencies of 20–60 Hz. Baseline viscoelastic measurements are recorded for the synthetic scaffolding material into which different cell lines will be injected and grown to form their own matrix. The methodology allows duration and repetitions of strain exposure to seeded scaffolding to be varied and for subsequent viscoelastic measurements to be compared. [Work supported by NIDCD.]

Paul J Remington - One of the best experts on this subject based on the ideXlab platform.