The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
Dong Zhou - One of the best experts on this subject based on the ideXlab platform.
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Motor trajectories in Automatisms and their quantitative analysis
Epilepsy Research, 2009Co-Authors: Xuhong Yang, Hongru Xu, Yufeng Tang, Dong Zeng, Lei Chen, Dong ZhouAbstract:Summary Objective To quantitatively analyze trajectory of movement in Automatisms with temporal lobe epilepsy (TLE) and frontal lobe epilepsy (FLE). Methods Twenty markers were attached to chosen body parts of patients, and 10 videos of seizures were recorded. The obtained videos were converted into digital matrices. Motor trajectories were established, the amplitude, frequency, limb distal–proximal amplitude ratio, and shoulder–abdominal amplitude ratio were calculated, analyzed and compared between two types of epilepsy. Results The average of transient limb distal–proximal ratios in Automatism patients with TLE was >3, which suggested that distal limb movements during TLE were predominant. However, the transient limb distal–proximal ratio in patients with FLE was Conclusion The quantification system may pave a new way for semiology study of epilepsy and is important in differential diagnosis of different types of epilepsy.
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Motor trajectories in Automatisms and their quantitative analysis.
Epilepsy research, 2008Co-Authors: Xuhong Yang, Hongru Xu, Yufeng Tang, Dong Zeng, Lei Chen, Dong ZhouAbstract:To quantitatively analyze trajectory of movement in Automatisms with temporal lobe epilepsy (TLE) and frontal lobe epilepsy (FLE). Twenty markers were attached to chosen body parts of patients, and 10 videos of seizures were recorded. The obtained videos were converted into digital matrices. Motor trajectories were established, the amplitude, frequency, limb distal-proximal amplitude ratio, and shoulder-abdominal amplitude ratio were calculated, analyzed and compared between two types of epilepsy. The average of transient limb distal-proximal ratios in Automatism patients with TLE was >3, which suggested that distal limb movements during TLE were predominant. However, the transient limb distal-proximal ratio in patients with FLE was <3, which indicated the predominance of proximal movements. The differences of motor trajectories between these two types of epilepsy were statistically significant. The quantification system may pave a new way for semiology study of epilepsy and is important in differential diagnosis of different types of epilepsy.
Xuhong Yang - One of the best experts on this subject based on the ideXlab platform.
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Motor trajectories in Automatisms and their quantitative analysis
Epilepsy Research, 2009Co-Authors: Xuhong Yang, Hongru Xu, Yufeng Tang, Dong Zeng, Lei Chen, Dong ZhouAbstract:Summary Objective To quantitatively analyze trajectory of movement in Automatisms with temporal lobe epilepsy (TLE) and frontal lobe epilepsy (FLE). Methods Twenty markers were attached to chosen body parts of patients, and 10 videos of seizures were recorded. The obtained videos were converted into digital matrices. Motor trajectories were established, the amplitude, frequency, limb distal–proximal amplitude ratio, and shoulder–abdominal amplitude ratio were calculated, analyzed and compared between two types of epilepsy. Results The average of transient limb distal–proximal ratios in Automatism patients with TLE was >3, which suggested that distal limb movements during TLE were predominant. However, the transient limb distal–proximal ratio in patients with FLE was Conclusion The quantification system may pave a new way for semiology study of epilepsy and is important in differential diagnosis of different types of epilepsy.
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Motor trajectories in Automatisms and their quantitative analysis.
Epilepsy research, 2008Co-Authors: Xuhong Yang, Hongru Xu, Yufeng Tang, Dong Zeng, Lei Chen, Dong ZhouAbstract:To quantitatively analyze trajectory of movement in Automatisms with temporal lobe epilepsy (TLE) and frontal lobe epilepsy (FLE). Twenty markers were attached to chosen body parts of patients, and 10 videos of seizures were recorded. The obtained videos were converted into digital matrices. Motor trajectories were established, the amplitude, frequency, limb distal-proximal amplitude ratio, and shoulder-abdominal amplitude ratio were calculated, analyzed and compared between two types of epilepsy. The average of transient limb distal-proximal ratios in Automatism patients with TLE was >3, which suggested that distal limb movements during TLE were predominant. However, the transient limb distal-proximal ratio in patients with FLE was <3, which indicated the predominance of proximal movements. The differences of motor trajectories between these two types of epilepsy were statistically significant. The quantification system may pave a new way for semiology study of epilepsy and is important in differential diagnosis of different types of epilepsy.
András Fogarasi - One of the best experts on this subject based on the ideXlab platform.
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a detailed analysis of frontal lobe seizure semiology in children younger than 7 years
Epilepsia, 2008Co-Authors: Eduardo Faveret, Thorsten Pieper, András Fogarasi, József Janszky, Ingrid TuxhornAbstract:Summary: Purpose: We sought to analyze semiology of seizure onset and evolution in young children with frontal lobe epilepsy (FLE), compare this with adult reports, and assess age-related differences. Methods: We analyzed 111 videotaped seizures from 14 patients with FLE based on focal cortical dysplasia aged 3‐81 months (mean, 30 months). Ictal events were categorized into behavioral, consciousness, autonomic, and sensory features, as well as motor patterns, which included tonic, clonic, epileptic spasm, and myoclonic seizure components. We developed a time-scaled datasheet to record each epileptic event as onset, very early, early, or late manifestation. Results: Patients had a high seizure frequency with up to 40 attacks/day; half of them showed a cluster tendency. Fortyseven percent of the seizures started in sleep. Mean duration of seizures was short (29 s). Most common seizure components were motor manifestations, mostly tonic‐clonic seizures, and epileptic spasms. Behavioral change was frequent, and hypermotor seizures were not seen. In five patients, the motor features were contralateral to the epileptic focus, including two children with asymmetric epileptic spasms. Secondarily generalized tonic‐clonic seizures (SGTCSs) were not recorded, but had been reported in the history of two patients. Complex motor Automatisms were not seen, whereas oral Automatism appeared in three children. Conclusions: Motor features are common in young children with FLE, as reported in adults. The characteristics, however, differ. Epileptic spasms and subtle behavioral change were frequent. Hypermotor seizures and complex motor Automatisms were not seen, and SGTCSs were unusual. Our results suggest that FLE in young children shows age-related features differing from those of adults. Key Words: Frontal lobe epilepsy— Seizure semiology—Children—Age.
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Electrode manipulation Automatism during temporal lobe seizures
Seizure, 2006Co-Authors: András Fogarasi, József Janszky, György Rásonyi, Anna Kelemen, Péter HalászAbstract:Summary Objective To describe clinical characteristics and lateralizing value of peri-ictal electrode manipulation Automatism (EMA) in patients with temporal lobe epilepsy (TLE) and compare our data with ictal manual Automatisms described in the literature. Methods Two-hundred and five videotaped seizures of 55 consecutive patients with refractory TLE and postoperatively seizure-free outcome were analyzed and EMA (tugging, scratching or adjusting the electrodes and cables) were monitored. Results Twenty-eight (51%) patients showed EMA during 47 (23%) seizures. Ictal start was noted in 22 seizures and in 19/22 cases EMA finished before the end of seizure. Ictal EMAs were always associated with automotor seizure components. During 25 seizures, exclusively postictal EMAs were observed. Electrode manipulation was presented during 24/112 left-sided and 23/93 right-sided seizures ( p =0.742). Peri-ictal EMA was unilateral (completed by one hand) in 24/47 seizures (10 ictal, 14 postictal); it was done by the hand ipsilateral to the seizure onset zone in 17/24 and by contralateral hand in 7/24 cases ( p =0.064). We observed concomitant contralateral dystonic posturing during 3/10 seizures with unilateral ictal EMA. Unilateral hand Automatism, temporally independent from the EMA appeared in 30 (64%) of the 47 seizures. Conclusion Peri-ictal EMA is a frequent phenomenon but shows no lateralizing value in TLE. The mechanism of EMA is in many ways dissimilar from that of earlier described manual Automatisms.
Bruce P. Hermann - One of the best experts on this subject based on the ideXlab platform.
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spitting Automatism in complex partial seizures a nondominant temporal localizing sign
Epilepsia, 1999Co-Authors: Nicholas F Voss, Georgia D Montouris, Keith G. Davies, Frederick A Boop, Bruce P. HermannAbstract:Summary: Purpose: Spitting as an ictal Automatism has been rarely reported. We aimed to establish its potential lateralizing and localizing significance. Methods: Review of patients undergoing surgery for intractable epilepsy at two comprehensive epilepsy centers. Results: Five patients were found who had spitting as a stereotyped Automatism of their complex partial seizures. All had evidence of right temporal ictal onset and underwent resective surgery. Two had tumors; one, a cavernous angioma; one, hippocampal gliosis, and one, hippocampal sclerosis. We found no instances of ictal spitting in patients with left hemisphere onset. Conclusions: Spitting as an Automatism in complex partial seizures, although uncommon, may be a localizing sign to the nondominant temporal lobe.
Soheyl Noachtar - One of the best experts on this subject based on the ideXlab platform.
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Significance of lateralization of upper limb Automatisms in temporal lobe epilepsy: A quantitative movement analysis
Epilepsia, 2010Co-Authors: Zulfiya Mirzadjanova, Astrid S. Peters, Jan Rémi, Candas Bilgin, João Paulo Silva Cunha, Soheyl NoachtarAbstract:Summary Purpose: To evaluate the significance of lateralization of ictal upper limb Automatisms in patients with temporal lobe epilepsy (TLE). Methods: Ictal upper limb Automatisms of 28 patients with temporal lobe epilepsy were quantified. Duration of Automatisms in relation to total seizure duration, movement speed, extent, length, and predominant frequencies of the movements were analyzed for both upper extremities separately and compared to the lateralization of the epileptogenic temporal lobe. Results: Predominantly ipsilateral upper limb Automatisms were more common (n = 19) than predominantly contralateral Automatisms (n = 9). The duration of ictal ipsilateral upper limb Automatisms was significantly longer than the duration of contralateral Automatisms (ipsilateral Automatisms: 29 of 86 s total seizure duration; contralateral Automatisms: 19 of 110 s total seizure duration; p = 0.048). Patients with ipsilateral upper limb Automatisms had more often exclusively unitemporal interictal epileptiform discharges (IEDs) (84.2%) than patients with contralateral Automatisms (11.1%; p
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Automatisms with preserved responsiveness: A lateralizing sign in psychomotor seizures
Neurology, 1995Co-Authors: Alois Ebner, Dudley S. Dinner, Soheyl Noachtar, Hans LüdersAbstract:This is a report of a 1-year prospective study to investigate how often Automatisms occur with preserved responsiveness in psychomotor seizures. Responsiveness is usually impaired or lost when Automatisms occur during psychomotor seizures. However, there are several anecdotal reports in the literature of patients who have Automatisms with preserved responsiveness (APRs). We evaluated 123 patients with temporal lobe epilepsy (57 patients [46%] left-sided, 48 patients [39%] right-sided, and 18 patients [15%] bitemporal) with video/EEG monitoring, testing responsiveness by asking the patient to respond verbally and to follow motor commands. Seven patients (5.6%) had preserved responsiveness in the presence of prominent Automatisms (lip smacking, swallowing). In 15 seizures, the responsiveness was adequately tested (3.6 questions per period of Automatism). Average seizure duration was 71.6 +/- 14.8 seconds (range, 45 to 100 seconds). Average duration of Automatisms was 59.5 +/- 13.5 seconds (range, 40 to 80 seconds). Ictal EEG was localized over the right temporal area in nine seizures, over the right hemisphere in five, and was nonlocalizable in one seizure. APRs never occurred in left-sided psychomotor seizures and occurred in 10% of the right temporal cases. In conclusion, APRs reliably lateralized to the right side in temporal lobe epilepsy.
