The Experts below are selected from a list of 204 Experts worldwide ranked by ideXlab platform
Maria De Lluc Joan - One of the best experts on this subject based on the ideXlab platform.
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Automobile Accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study.
American journal of respiratory and critical care medicine, 1998Co-Authors: Ferran Barbé, Larry J. Findley, Jordi Pericas, Araceli Muñoz, Josep M. Antó, Alvar Agusti, Maria De Lluc JoanAbstract:To investigate the association between sleep apnea syndrome (SAS) and Automobile Accidents, and to evaluate potential underlying mechanisms, we prospectively recruited 60 consecutive patients with SAS (apnea-hypopnea index, 58 +/- 3 h-1) and 60 healthy control subjects, matched for sex and age. The number of Automobile Accidents during the past 3 yr was obtained from participants and insurance companies. We quantified the degree of daytime sleepiness (Epworth scale), anxiety and depression (Beck tests), and we assessed the level of vigilance (PVT 192) and driving performance (Steer-Clear). Patients had more Accidents than control subjects (OR: 2.3; 95% CI: 0.97 to 5.33) and were more likely to have had more than one Accident (OR: 5.2; 95% CI: 1.07 to 25.29, p < 0.05). These differences persisted after stratification for km/yr, age, and alcohol consumption. Patients were more somnolent, anxious, and depressed than control subjects (p < 0.01), and they had a lower level of vigilance and poorer driving performance (p < 0.01). Yet, we did not find any correlation between the degree of daytime sleepiness, anxiety, depression, the number of respiratory events, nocturnal hypoxemia, level of vigilance, or driving simulator performance and the risk of Automobile Accidents among SAS patients. In conclusion, patients with SAS have an increased risk of Automobile Accidents. None of the clinical or physiological markers commonly used to define disease severity appear able to discriminate those patients at higher risk of having an Automobile Accident.
Ferran Barbé - One of the best experts on this subject based on the ideXlab platform.
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Automobile Accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study.
American journal of respiratory and critical care medicine, 1998Co-Authors: Ferran Barbé, Larry J. Findley, Jordi Pericas, Araceli Muñoz, Josep M. Antó, Alvar Agusti, Maria De Lluc JoanAbstract:To investigate the association between sleep apnea syndrome (SAS) and Automobile Accidents, and to evaluate potential underlying mechanisms, we prospectively recruited 60 consecutive patients with SAS (apnea-hypopnea index, 58 +/- 3 h-1) and 60 healthy control subjects, matched for sex and age. The number of Automobile Accidents during the past 3 yr was obtained from participants and insurance companies. We quantified the degree of daytime sleepiness (Epworth scale), anxiety and depression (Beck tests), and we assessed the level of vigilance (PVT 192) and driving performance (Steer-Clear). Patients had more Accidents than control subjects (OR: 2.3; 95% CI: 0.97 to 5.33) and were more likely to have had more than one Accident (OR: 5.2; 95% CI: 1.07 to 25.29, p < 0.05). These differences persisted after stratification for km/yr, age, and alcohol consumption. Patients were more somnolent, anxious, and depressed than control subjects (p < 0.01), and they had a lower level of vigilance and poorer driving performance (p < 0.01). Yet, we did not find any correlation between the degree of daytime sleepiness, anxiety, depression, the number of respiratory events, nocturnal hypoxemia, level of vigilance, or driving simulator performance and the risk of Automobile Accidents among SAS patients. In conclusion, patients with SAS have an increased risk of Automobile Accidents. None of the clinical or physiological markers commonly used to define disease severity appear able to discriminate those patients at higher risk of having an Automobile Accident.
Philippe-emmanuel Coiffait - One of the best experts on this subject based on the ideXlab platform.
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Blood concentration of milnacipran in a case of a fatal Automobile Accident.
Journal of analytical toxicology, 2002Co-Authors: Pok Phak Rop, Marie H. Sournac, Joëlle Burle, M. Fornaris, Philippe-emmanuel CoiffaitAbstract:A fatal Automobile Accident involving milnacipran and ethyl alcohol is reported. The drug was identified and quantitated in blood by high-performance liquid chromatography-diode-array detection. The concentration of milnacipran in peripheral blood was 3.15 microg/mL exceeded 10.5 times the therapeutic concentration. The blood ethyl alcohol level was 1.3 g/L.
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blood concentration of milnacipran in a case of a fatal Automobile Accident
Journal of Analytical Toxicology, 2002Co-Authors: Pok Phak Rop, Marie H. Sournac, Joëlle Burle, M. Fornaris, Philippe-emmanuel CoiffaitAbstract:A fatal Automobile Accident involving milnacipran and ethyl alcohol is reported. The drug was identified and quantitated in blood by high-performance liquid chromatography-diode-array detection. The concentration of milnacipran in peripheral blood was 3.15 microg/mL exceeded 10.5 times the therapeutic concentration. The blood ethyl alcohol level was 1.3 g/L. Language: en
Alvar Agusti - One of the best experts on this subject based on the ideXlab platform.
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Automobile Accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study.
American journal of respiratory and critical care medicine, 1998Co-Authors: Ferran Barbé, Larry J. Findley, Jordi Pericas, Araceli Muñoz, Josep M. Antó, Alvar Agusti, Maria De Lluc JoanAbstract:To investigate the association between sleep apnea syndrome (SAS) and Automobile Accidents, and to evaluate potential underlying mechanisms, we prospectively recruited 60 consecutive patients with SAS (apnea-hypopnea index, 58 +/- 3 h-1) and 60 healthy control subjects, matched for sex and age. The number of Automobile Accidents during the past 3 yr was obtained from participants and insurance companies. We quantified the degree of daytime sleepiness (Epworth scale), anxiety and depression (Beck tests), and we assessed the level of vigilance (PVT 192) and driving performance (Steer-Clear). Patients had more Accidents than control subjects (OR: 2.3; 95% CI: 0.97 to 5.33) and were more likely to have had more than one Accident (OR: 5.2; 95% CI: 1.07 to 25.29, p < 0.05). These differences persisted after stratification for km/yr, age, and alcohol consumption. Patients were more somnolent, anxious, and depressed than control subjects (p < 0.01), and they had a lower level of vigilance and poorer driving performance (p < 0.01). Yet, we did not find any correlation between the degree of daytime sleepiness, anxiety, depression, the number of respiratory events, nocturnal hypoxemia, level of vigilance, or driving simulator performance and the risk of Automobile Accidents among SAS patients. In conclusion, patients with SAS have an increased risk of Automobile Accidents. None of the clinical or physiological markers commonly used to define disease severity appear able to discriminate those patients at higher risk of having an Automobile Accident.
Josep M. Antó - One of the best experts on this subject based on the ideXlab platform.
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Automobile Accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study.
American journal of respiratory and critical care medicine, 1998Co-Authors: Ferran Barbé, Larry J. Findley, Jordi Pericas, Araceli Muñoz, Josep M. Antó, Alvar Agusti, Maria De Lluc JoanAbstract:To investigate the association between sleep apnea syndrome (SAS) and Automobile Accidents, and to evaluate potential underlying mechanisms, we prospectively recruited 60 consecutive patients with SAS (apnea-hypopnea index, 58 +/- 3 h-1) and 60 healthy control subjects, matched for sex and age. The number of Automobile Accidents during the past 3 yr was obtained from participants and insurance companies. We quantified the degree of daytime sleepiness (Epworth scale), anxiety and depression (Beck tests), and we assessed the level of vigilance (PVT 192) and driving performance (Steer-Clear). Patients had more Accidents than control subjects (OR: 2.3; 95% CI: 0.97 to 5.33) and were more likely to have had more than one Accident (OR: 5.2; 95% CI: 1.07 to 25.29, p < 0.05). These differences persisted after stratification for km/yr, age, and alcohol consumption. Patients were more somnolent, anxious, and depressed than control subjects (p < 0.01), and they had a lower level of vigilance and poorer driving performance (p < 0.01). Yet, we did not find any correlation between the degree of daytime sleepiness, anxiety, depression, the number of respiratory events, nocturnal hypoxemia, level of vigilance, or driving simulator performance and the risk of Automobile Accidents among SAS patients. In conclusion, patients with SAS have an increased risk of Automobile Accidents. None of the clinical or physiological markers commonly used to define disease severity appear able to discriminate those patients at higher risk of having an Automobile Accident.
