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Pulok K Mukherjee - One of the best experts on this subject based on the ideXlab platform.
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development of Ayurveda tradition to trend
Journal of Ethnopharmacology, 2017Co-Authors: Pulok K Mukherjee, Ranjit K Harwansh, Shiv Bahadur, Subhadip Banerjee, Joydeb Chanda, Sayan Biswas, Sk Milan Ahmmed, C K KatiyarAbstract:Abstract Ethnopharmacological relevance Ayurveda entails a scientific tradition of harmonious living and its origin can be traced from ancient knowledge in Rigveda and Atharvaveda . Ayurveda is a traditional healthcare system of Indian medicine since ancient times. Several Ayurvedic medicines have been exploiting for treatment and management of various diseases in human beings. The several drugs have been developed and practiced from Ayurveda since ancient time to modern practice as ‘tradition to trend’. The potential of Ayurvedic medicine needs to be explored further with modern scientific validation approaches for better therapeutic leads. Aim of the study The present study was aimed to explore the various aspects of Ayurveda and inspired drug discovery approaches for its promotion and development. Materials and methods We have reviewed all the literature related to the history and application of Ayurvedic herbs. Various aspects for the quality control, standardization, chemo-profiling, and metabolite fingerprinting for quality evaluation of Ayurvedic drugs. The development of Ayurvedic drugs is gaining momentum with the perspectives of safety, efficacy and quality for promotion and management of human health. Scientific documentation, process validation and several others significant parameters are key points, which can ensure the quality, safety and effectiveness of Ayurvedic drugs. Results The present review highlights on the major goal of Ayurveda and their significant role in healthcare system. Ayurveda deals with several classical formulations including arka, asavas, aristas, churna, taila, vati, gutika, bhasma etc. There are several lead molecules that have been developed from the Ayurvedic herbs, which have various significant therapeutic activities. Chemo-profiling of Ayurvedic drug is essential in order to assess the quality of products. It deals with bioactive compound quantification, spurious and allied drug determination, chromatographic fingerprinting, standardization, stability and quality consistency of Ayurvedic products. Conclusions Scientific validation and the documentation of Ayurvedic drugs are very essential for its quality evaluation and global acceptance. Therapeutic efficacy of Ayurvedic herbs may be enhanced with high quality, which can be achieved by identity, purity, safety, drug content, physical and biological properties. Ayurvedic medicines need be explored with the modern scientific approaches for its validation. Therefore, an attempt has been made in the present review to highlight the crucial aspects that need to be considered for the promotion and development of Ayurvedic medicine.
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Integrated approaches towards drug development from Ayurveda and other Indian system of medicines.
Journal of ethnopharmacology, 2005Co-Authors: Pulok K Mukherjee, Atul WahileAbstract:Biodiversity of natural resources has served not only for the primary human needs but also for health care, since time immemorial. The Indian subcontinent, with the history of one of the oldest civilization, harbors many traditional health care systems. Their development was supported by the diverse biodiversity in flora and fauna due to variations in geographical landscaping. Ayurveda, whose history goes back to 5000 b.c., is one of the ancient health care systems. The Ayurveda was developed through daily life experiences with the mutual relationship between mankind and nature. The ancient text of Ayurveda reports more than 2000 plant species for their therapeutic potentials. Besides Ayurveda, other traditional and folklore systems of health care were developed in the different time periods in Indian subcontinent, where more than 7500 plant species were used. According to a WHO estimate, about 80% of the world population relies on traditional systems of medicines for primary health care, where plants form the dominant component over other natural resources. Renewed interest of developing as well as developed countries in the natural resources has opened new horizons for the exploration of natural sources with the perspectives of safety and efficacy. The development of these traditional systems of medicines with the perspectives of safety, efficacy and quality will help not only to preserve this traditional heritage but also to rationalize the use of natural products in the health care. Until recent past, the nature was considered as a compendium for templates of new chemical entities (NCEs). The plant species mentioned in the ancient texts of these Ayurveda and other Indian systems of medicines may be explored with the modern scientific approaches for better leads in the health care.
Atul Wahile - One of the best experts on this subject based on the ideXlab platform.
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Integrated approaches towards drug development from Ayurveda and other Indian system of medicines.
Journal of ethnopharmacology, 2005Co-Authors: Pulok K Mukherjee, Atul WahileAbstract:Biodiversity of natural resources has served not only for the primary human needs but also for health care, since time immemorial. The Indian subcontinent, with the history of one of the oldest civilization, harbors many traditional health care systems. Their development was supported by the diverse biodiversity in flora and fauna due to variations in geographical landscaping. Ayurveda, whose history goes back to 5000 b.c., is one of the ancient health care systems. The Ayurveda was developed through daily life experiences with the mutual relationship between mankind and nature. The ancient text of Ayurveda reports more than 2000 plant species for their therapeutic potentials. Besides Ayurveda, other traditional and folklore systems of health care were developed in the different time periods in Indian subcontinent, where more than 7500 plant species were used. According to a WHO estimate, about 80% of the world population relies on traditional systems of medicines for primary health care, where plants form the dominant component over other natural resources. Renewed interest of developing as well as developed countries in the natural resources has opened new horizons for the exploration of natural sources with the perspectives of safety and efficacy. The development of these traditional systems of medicines with the perspectives of safety, efficacy and quality will help not only to preserve this traditional heritage but also to rationalize the use of natural products in the health care. Until recent past, the nature was considered as a compendium for templates of new chemical entities (NCEs). The plant species mentioned in the ancient texts of these Ayurveda and other Indian systems of medicines may be explored with the modern scientific approaches for better leads in the health care.
M Parappagoudra - One of the best experts on this subject based on the ideXlab platform.
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A Clinical case study on Dhanyak Gokshur Ghrita Yavakshar Uttar basti in the management of Mutraghata w.s.r. to Benign Prostatic Hyperplasia
Ayurveda Sahiti Prabha, 2021Co-Authors: Jaiswal Shailesh, Toshikhane Hemant, Dhule Mukund, M ParappagoudraAbstract:Benign Prostatic Hyperplasia is a common senile disease. The present modern conservative management includes use of alpha blockers and 5 alpha reductase inhibitors. In operative management various type of operative procedure may be done, out of which most commonly done now-a-days is TURP. However, both of these modalities cause various side effects. Through Ayurveda we can find solution for this burning problem of society. In Ayurved Samhitas, symptoms of Benign Prostate Hyperplasia described under Mutraghata disease. There are 12 types of Mutraghata; one of them is Vatashthila, which can be correlated with Benign Prostatic Hyperplasia disease. The general treatment of Mutraghata includes Uttar basti . Though Uttar basti is a traditionally used therapy, its efficacy with Dhanyak Gokshur Ghrita Yavakshar is not yet evaluated in the management of BPH. Uttar basti is cost effective and it may avoid surgery which ultimately results in increased quality of life of patients. So, in present clinical study, efficacy of Dhanyak Gokshur Ghrita Yavakshar Uttar basti in Vatashthila with special reference to Benign Prostatic Hyperplasia is evaluated
Ts Dudhamal - One of the best experts on this subject based on the ideXlab platform.
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EFFICACY OF Ayurveda FORMULATIONS AND BASTI CHIKITSA ON MUTRAGHATA W.S.R. TO BENIGN PROSTATIC HYPERPLASIA: A REVIEW ON RESEARCHES CONDUCTED AT GUJARAT AYURVED UNIVERSITY, JAMNAGAR
International Journal of Ayurveda and Pharma Research, 2015Co-Authors: G Banothe, Vd Mahanta, Sk Gupta, Ts DudhamalAbstract:Benign Prostatic Hyperplasia (BPH) is major geriatric problem of obstructive uropathic disorders described in Ayurveda classic as one type of Mutraghata (urinary disorders). Twelve types of Mutraghata reflect the symptoms of retention, incomplete voiding, dribbling, hesitancy, incontinence of urine, etc. These are basically presented the features related to the Lower Urinary Tract Symptoms (LUTS) and can be co-related with Benign Prostatic Hyperplasia (BPH) in modern parlance. BPH is a non-malignant enlargement of the prostate gland, caused by the excessive growth of prostatic nodules. The overall incidence rate of BPH is about 15 per 1000 men per year. The conservative treatments have been mentioned to relieve the obstructive uropathy by reducing prostate size and enhancing the tone of urinary bladder musculature in contemporary medical science. Similarly in Ayurveda also, various researches are going on to find out a suitable treatment option to manage Mutraghata. In the Sushruta Samhita the choice of treatment for Mutraghata is Uttara Basti as Shodhan Chikitsa. In this review, in most of the studies Matra Basti was given in one group of patients and showed the encouraging results. This review article is attributed to the researches on Mutraghata carried out at I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar, Gujarat
C K Katiyar - One of the best experts on this subject based on the ideXlab platform.
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development of Ayurveda tradition to trend
Journal of Ethnopharmacology, 2017Co-Authors: Pulok K Mukherjee, Ranjit K Harwansh, Shiv Bahadur, Subhadip Banerjee, Joydeb Chanda, Sayan Biswas, Sk Milan Ahmmed, C K KatiyarAbstract:Abstract Ethnopharmacological relevance Ayurveda entails a scientific tradition of harmonious living and its origin can be traced from ancient knowledge in Rigveda and Atharvaveda . Ayurveda is a traditional healthcare system of Indian medicine since ancient times. Several Ayurvedic medicines have been exploiting for treatment and management of various diseases in human beings. The several drugs have been developed and practiced from Ayurveda since ancient time to modern practice as ‘tradition to trend’. The potential of Ayurvedic medicine needs to be explored further with modern scientific validation approaches for better therapeutic leads. Aim of the study The present study was aimed to explore the various aspects of Ayurveda and inspired drug discovery approaches for its promotion and development. Materials and methods We have reviewed all the literature related to the history and application of Ayurvedic herbs. Various aspects for the quality control, standardization, chemo-profiling, and metabolite fingerprinting for quality evaluation of Ayurvedic drugs. The development of Ayurvedic drugs is gaining momentum with the perspectives of safety, efficacy and quality for promotion and management of human health. Scientific documentation, process validation and several others significant parameters are key points, which can ensure the quality, safety and effectiveness of Ayurvedic drugs. Results The present review highlights on the major goal of Ayurveda and their significant role in healthcare system. Ayurveda deals with several classical formulations including arka, asavas, aristas, churna, taila, vati, gutika, bhasma etc. There are several lead molecules that have been developed from the Ayurvedic herbs, which have various significant therapeutic activities. Chemo-profiling of Ayurvedic drug is essential in order to assess the quality of products. It deals with bioactive compound quantification, spurious and allied drug determination, chromatographic fingerprinting, standardization, stability and quality consistency of Ayurvedic products. Conclusions Scientific validation and the documentation of Ayurvedic drugs are very essential for its quality evaluation and global acceptance. Therapeutic efficacy of Ayurvedic herbs may be enhanced with high quality, which can be achieved by identity, purity, safety, drug content, physical and biological properties. Ayurvedic medicines need be explored with the modern scientific approaches for its validation. Therefore, an attempt has been made in the present review to highlight the crucial aspects that need to be considered for the promotion and development of Ayurvedic medicine.