The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform

Juan P. Barret - One of the best experts on this subject based on the ideXlab platform.

  • effects of burn wound excision on Bacterial Colonization and invasion
    Plastic and Reconstructive Surgery, 2003
    Co-Authors: David N. Herndon, Juan P. Barret
    Abstract:

    Rates of survival after thermal injury have improved in the past two decades, and rates of wound infections and sepsis have decreased during the same period. Early excision has been advocated as one of the major factors, but its safety and efficacy and the exact timing of burn excision are still under debate. It was hypothesized that acute burn wound excision (in the first 24 hours after burning) would be superior to conservative treatment and delayed excision in preventing Bacterial Colonization and invasion.,juries were Twenty consecutive patients with thermal injuries were studied. Twelve patients underwent acute burn wound excision, and eight patients underwent conservative treatment and delayed excision. The second group of patients received topical treatments in another facility and underwent delayed excision after transfer to our set-vice, on postburn day 6. Quantitative bacteriological assessments of the excised wound and biopsy samples of the wound bed, obtained before autografting and/or homografting, were performed. The effects of time on Bacterial counts, differences between superficial and deep biopsy samples, and the effects of early versus late debridement were studied. Patients admitted early exhibited Bacterial counts of less than 105 bacteria per grain of tissue. Patients in this group did not experience infection or graft loss. Patients admitted late exhibited counts of more than 105 bacteria (p = 0.001, compared with early admission). Three patients in the late excision group experienced infection and graft loss (p <0.05, compared with the early excision group). Burn wound excision significantly decreased Bacterial Colonization for all patients (p <0.001). Greater Bacterial Colonization and higher rates of infection were correlated with topical treatment and late excision (p <0.001). It is concluded that burn wound excision significantly reduces Bacterial Colonization. Patients who undergo topical treatment and delayed burn wound excision exhibit greater Bacterial Colonization and increased rates of infection. Acute burn wound excision should be considered for all full-thickness burns.

  • effects of burn wound excision on Bacterial Colonization and invasion
    Plastic and Reconstructive Surgery, 2003
    Co-Authors: Juan P. Barret, David N. Herndon
    Abstract:

    Rates of survival after thermal injury have improved in the past two decades, and rates of wound infections and sepsis have decreased during the same period. Early excision has been advocated as one of the major factors, but its safety and efficacy and the exact timing of burn excision are still under debate. It was hypothesized that acute burn wound excision (in the first 24 hours after burning) would be superior to conservative treatment and delayed excision in preventing Bacterial Colonization and invasion. Twenty consecutive patients with thermal injuries were studied. Twelve patients underwent acute burn wound excision, and eight patients underwent conservative treatment and delayed excision. The second group of patients received topical treatments in another facility and underwent delayed excision after transfer to our service, on postburn day 6. Quantitative bacteriological assessments of the excised wound and biopsy samples of the wound bed, obtained before autografting and/or homografting, were performed. The effects of time on Bacterial counts, differences between superficial and deep biopsy samples, and the effects of early versus late debridement were studied. Patients admitted early exhibited Bacterial counts of less than 10 bacteria per gram of tissue. Patients in this group did not experience infection or graft loss. Patients admitted late exhibited counts of more than 10 bacteria (p = 0.001, compared with early admission). Three patients in the late excision group experienced infection and graft loss (p < 0.05, compared with the early excision group). Burn wound excision significantly decreased Bacterial Colonization for all patients (p < 0.001). Greater Bacterial Colonization and higher rates of infection were correlated with topical treatment and late excision (p < 0.001). It is concluded that burn wound excision significantly reduces Bacterial Colonization. Patients who undergo topical treatment and delayed burn wound excision exhibit greater Bacterial Colonization and increased rates of infection. Acute burn wound excision should be considered for all full-thickness burns.

David N. Herndon - One of the best experts on this subject based on the ideXlab platform.

  • effects of burn wound excision on Bacterial Colonization and invasion
    Plastic and Reconstructive Surgery, 2003
    Co-Authors: David N. Herndon, Juan P. Barret
    Abstract:

    Rates of survival after thermal injury have improved in the past two decades, and rates of wound infections and sepsis have decreased during the same period. Early excision has been advocated as one of the major factors, but its safety and efficacy and the exact timing of burn excision are still under debate. It was hypothesized that acute burn wound excision (in the first 24 hours after burning) would be superior to conservative treatment and delayed excision in preventing Bacterial Colonization and invasion.,juries were Twenty consecutive patients with thermal injuries were studied. Twelve patients underwent acute burn wound excision, and eight patients underwent conservative treatment and delayed excision. The second group of patients received topical treatments in another facility and underwent delayed excision after transfer to our set-vice, on postburn day 6. Quantitative bacteriological assessments of the excised wound and biopsy samples of the wound bed, obtained before autografting and/or homografting, were performed. The effects of time on Bacterial counts, differences between superficial and deep biopsy samples, and the effects of early versus late debridement were studied. Patients admitted early exhibited Bacterial counts of less than 105 bacteria per grain of tissue. Patients in this group did not experience infection or graft loss. Patients admitted late exhibited counts of more than 105 bacteria (p = 0.001, compared with early admission). Three patients in the late excision group experienced infection and graft loss (p <0.05, compared with the early excision group). Burn wound excision significantly decreased Bacterial Colonization for all patients (p <0.001). Greater Bacterial Colonization and higher rates of infection were correlated with topical treatment and late excision (p <0.001). It is concluded that burn wound excision significantly reduces Bacterial Colonization. Patients who undergo topical treatment and delayed burn wound excision exhibit greater Bacterial Colonization and increased rates of infection. Acute burn wound excision should be considered for all full-thickness burns.

  • effects of burn wound excision on Bacterial Colonization and invasion
    Plastic and Reconstructive Surgery, 2003
    Co-Authors: Juan P. Barret, David N. Herndon
    Abstract:

    Rates of survival after thermal injury have improved in the past two decades, and rates of wound infections and sepsis have decreased during the same period. Early excision has been advocated as one of the major factors, but its safety and efficacy and the exact timing of burn excision are still under debate. It was hypothesized that acute burn wound excision (in the first 24 hours after burning) would be superior to conservative treatment and delayed excision in preventing Bacterial Colonization and invasion. Twenty consecutive patients with thermal injuries were studied. Twelve patients underwent acute burn wound excision, and eight patients underwent conservative treatment and delayed excision. The second group of patients received topical treatments in another facility and underwent delayed excision after transfer to our service, on postburn day 6. Quantitative bacteriological assessments of the excised wound and biopsy samples of the wound bed, obtained before autografting and/or homografting, were performed. The effects of time on Bacterial counts, differences between superficial and deep biopsy samples, and the effects of early versus late debridement were studied. Patients admitted early exhibited Bacterial counts of less than 10 bacteria per gram of tissue. Patients in this group did not experience infection or graft loss. Patients admitted late exhibited counts of more than 10 bacteria (p = 0.001, compared with early admission). Three patients in the late excision group experienced infection and graft loss (p < 0.05, compared with the early excision group). Burn wound excision significantly decreased Bacterial Colonization for all patients (p < 0.001). Greater Bacterial Colonization and higher rates of infection were correlated with topical treatment and late excision (p < 0.001). It is concluded that burn wound excision significantly reduces Bacterial Colonization. Patients who undergo topical treatment and delayed burn wound excision exhibit greater Bacterial Colonization and increased rates of infection. Acute burn wound excision should be considered for all full-thickness burns.

Lorene Schweig - One of the best experts on this subject based on the ideXlab platform.

L. Marchetti - One of the best experts on this subject based on the ideXlab platform.

  • Incidence and risk factors for respiratory tract Bacterial Colonization and infection in lung transplant recipients
    European Journal of Clinical Microbiology & Infectious Diseases, 2021
    Co-Authors: L. Paglicci, V. Borgo, N. Lanzarone, M. Fabbiani, C. Cassol, Mg. Cusi, M. Valassina, S. Scolletta, E. Bargagli, L. Marchetti
    Abstract:

    To evaluate incidence of and risk factors for respiratory Bacterial Colonization and infections within 30 days from lung transplantation (LT). We retrospectively analyzed microbiological and clinical data from 94 patients transplanted for indications other than cystic fibrosis, focusing on the occurrence of Bacterial respiratory Colonization or infection during 1 month of follow-up after LT. Thirty-three percent of patients developed lower respiratory Bacterial Colonization. Bilateral LT and chronic heart diseases were independently associated to a higher risk of overall Bacterial Colonization. Peptic diseases conferred a higher risk of multi-drug resistant (MDR) Colonization, while longer duration of aerosol prophylaxis was associated with a lower risk. Overall, 35% of lung recipients developed Bacterial pneumonia. COPD (when compared to idiopathic pulmonary fibrosis, IPF) and higher BMI were associated to a lower risk of Bacterial infection. A higher risk of MDR infection was observed in IPF and in patients with pre-transplant Colonization and infections. The risk of post-LT respiratory infections could be stratified by considering several factors (indication for LT, type of LT, presence of certain comorbidities, and microbiologic assessment before LT). A wider use of early nebulized therapies could be useful to prevent MDR Colonization, thus potentially lowering infectious risk.

Kelley Evens - One of the best experts on this subject based on the ideXlab platform.