The Experts below are selected from a list of 531 Experts worldwide ranked by ideXlab platform
Ryan D. Murtagh - One of the best experts on this subject based on the ideXlab platform.
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Pathognomonic MR imaging findings in Balo Concentric Sclerosis
AJNR. American journal of neuroradiology, 2001Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. Rojiani, F. Reed MurtaghAbstract:Irregular, Concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo Concentric Sclerosis (BCS), a rare but recognized variant of multiple Sclerosis. Differentiating BCS from multiple Sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be pathognomonic.
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Pathognomonic MR Imaging Findings in Balo Concentric Sclerosis
2000Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. RojianiAbstract:Summary: Irregular, Concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo Concentric Sclerosis (BCS), a rare but recog-nized variant of multiple Sclerosis. Differentiating BCS from multiple Sclerosis or neoplasm can be difficult clini-cally, but MR imaging findings noted in this case may be pathognomonic. Balo Concentric Sclerosis (BCS) is widely be-lieved to be a rare variant of multiple Sclerosis. It may present as clinically similar to multiple scle-rosis, affecting young adults with mild cognitive impairment without frank dementia, or be associ-ated with altered behavior and focal CNS deficits. Historically, the diagnosis was made post mortem or histopathologically in the presence of specifi
Lippincott Williams Wilkins - One of the best experts on this subject based on the ideXlab platform.
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Baló Concentric Sclerosis evolving from apparent tumefactive demyelination
Neurology, 2017Co-Authors: Lippincott Williams WilkinsAbstract:In the Clinical/Scientific Note “Balo Concentric Sclerosis evolving from apparent tumefactive demyelination” by T.A. Hardy et …
D A Graeb - One of the best experts on this subject based on the ideXlab platform.
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Diffusion-weighted imaging findings in Balo Concentric Sclerosis.
The British Journal of Radiology, 2006Co-Authors: Eoin C. Kavanagh, Manraj K.s. Heran, D.m. Fenton, J S Lapointe, R A Nugent, D A GraebAbstract:Balo Concentric Sclerosis is a rare demyelinating disease. Pathognomonic features have been previously described. Diffusion-wighted imaging findings have not been previously described in Balo Concentric Sclerosis. We describe the diffusion-weighted imaging findings in a 45-year-old lady with Balo Concentric Sclerosis. Diffusion-weighted imaging offers insight into the possible pathophysiology of this rare disease.
Jamie T. Caracciolo - One of the best experts on this subject based on the ideXlab platform.
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Pathognomonic MR imaging findings in Balo Concentric Sclerosis
AJNR. American journal of neuroradiology, 2001Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. Rojiani, F. Reed MurtaghAbstract:Irregular, Concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo Concentric Sclerosis (BCS), a rare but recognized variant of multiple Sclerosis. Differentiating BCS from multiple Sclerosis or neoplasm can be difficult clinically, but MR imaging findings noted in this case may be pathognomonic.
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Pathognomonic MR Imaging Findings in Balo Concentric Sclerosis
2000Co-Authors: Jamie T. Caracciolo, Ryan D. Murtagh, Amyn M. RojianiAbstract:Summary: Irregular, Concentric zones of increased signal on T2-weighted cranial MR imaging studies may strongly suggest Balo Concentric Sclerosis (BCS), a rare but recog-nized variant of multiple Sclerosis. Differentiating BCS from multiple Sclerosis or neoplasm can be difficult clini-cally, but MR imaging findings noted in this case may be pathognomonic. Balo Concentric Sclerosis (BCS) is widely be-lieved to be a rare variant of multiple Sclerosis. It may present as clinically similar to multiple scle-rosis, affecting young adults with mild cognitive impairment without frank dementia, or be associ-ated with altered behavior and focal CNS deficits. Historically, the diagnosis was made post mortem or histopathologically in the presence of specifi
Tanuja Chitnis - One of the best experts on this subject based on the ideXlab platform.
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Original Article Balo ́ Concentric Sclerosis in Children: A Case
2016Co-Authors: Jenny J. Linnoila, Tanuja ChitnisAbstract:Balo ́ Concentric Sclerosis is a unique and rare phenomenon in demyelinating disease. Typically thought of as a subtype of multiple Sclerosis, Balo ́ Concentric Sclerosis is characterized pathologically by striking rings of demyelination alternating with areas of pre-served myelination. Its exact prevalence in adult and especially pediatric populations is unknown. Although traditionally considered to be an acute and fatal disease of adults, there are a handful of reports of Balo ́ Concentric Sclerosis cases in pediatric patients. Here we report Balo ́ Concentric Sclerosis–like demyelinating disease in 3 female pediatric patients, representing 2.2 % of a cohort of 134 pediatric patients with demyelinating diseases who have been seen in our center since 2005. The relatively high prevalence of Baló Concentric Sclerosis–like cases in our pediatric demyelinating diseases center, none of which have been fatal, supports the premise that the developing immune and central nervous systems may manifest and respond to demyelinating disease differently from adults
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Balo Concentric Sclerosis in children: a case series.
Journal of Child Neurology, 2014Co-Authors: Jenny J. Linnoila, Tanuja ChitnisAbstract:Balo Concentric Sclerosis is a unique and rare phenomenon in demyelinating disease. Typically thought of as a subtype of multiple Sclerosis, Balo Concentric Sclerosis is characterized pathologicall...
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CADASIL mutation and Balo Concentric Sclerosis: A link between demyelination and ischemia?
Neurology, 2012Co-Authors: Tanuja Chitnis, Travis J. HollmannAbstract:A 26-year-old man of Portuguese descent with no significant past medical history presents with subacute onset of right-sided hemiparesis and aphasia, with marked expressive aphasia, word-finding difficulty, and rare paraphrasic errors. Examination demonstrated right central facial weakness, 2–3/5 strength in the right arm and leg, and dysmetria in the right upper and lower extremities. Reflexes were hyperactive on the right with a right-sided Babinski response. MRI of the brain showed multiple bilateral Concentric ring-like structures in the centrum semiovale and the corona radiata on T2 imaging (figure,A), consistent with the pattern of Balo Concentric Sclerosis. There was associated restricted diffusion in 3 lesions and incomplete ring enhancement in 1 lesion. CSF analysis showed 30 leukocytes (79% lymphocytes, 4% monocytes), erythrocyte count was 850, and oligoclonal bands were absent. He was treated with 1 g of IV methylprednisolone daily for 5 days, with little improvement. He then underwent 5 plasmapheresis exchanges, with significant improvement of motor, sensory, speech deficits, and gait. Forty-five days after discharge, his examination showed 4+/5 strength in the right intrinsic muscles of the hand and a right-sided positional tremor. Gait and tandem gait were normal. He was placed …
