The Experts below are selected from a list of 1512 Experts worldwide ranked by ideXlab platform
Ioannis G Pallikaris - One of the best experts on this subject based on the ideXlab platform.
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combined topical application of a regenerative agent with a Bandage Contact Lens for the treatment of persistent epithelial defects
Cornea, 2014Co-Authors: George D Kymionis, Michael A Grentzelos, Vasilios F Diakonis, Dimitrios A Liakopoulos, Nektarios E Klados, Konstantinos I Tsoulnaras, Miltiadis K Tsilimbaris, Ioannis G PallikarisAbstract:Purpose The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a Bandage Contact Lens (BCL). Methods This is a case series. Results Three patients suffering from a PED for 4-8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4-21 days, and no side effects were noted. Conclusions The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.
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efficacy of 2 types of silicone hydrogel Bandage Contact Lenses after photorefractive keratectomy
Journal of Cataract and Refractive Surgery, 2009Co-Authors: Michael A Grentzelos, Sotiris Plainis, Nikolaos Astyrakakis, Vasilios F Diakonis, George D Kymionis, Panagiotis Kallinikos, Ioannis G PallikarisAbstract:METHODS:In this prospective study, 1eyeof patients having bilateral PRKwas randomly fittedwith a Bandage Contact Lens of lotrafilcon A (Night & Day) and the fellow eye, with a Bandage Contact Lens of lotrafilcon B (O2Optix). The patients and the examiner were masked to which Bandage Contact Lens type was in which eye. Patients were examined on the day of surgery and 1, 3, and 5 days postoperatively. Postoperative examinations included uncorrected distance visual acuity and slitlamp biomicroscopy to assess epithelial defect size. Subjective evaluation of pain and vision was recorded 1, 2, 3, and 4 days postoperatively. RESULTS: The study enrolled 44 patients (88 eyes). The mean epithelial defect size immediately after surgery was 47.0 mm 2 with both types of Bandage Contact Lenses. There was no statistically significant difference in epithelial defect size between the 2 Lenses at any postoperative visit. Three days postoperatively, reepithelialization was complete in 75.0% of eyes in the lotrafilcon A group and 72.7% of the eyes in the lotrafilcon B group. CONCLUSION: There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel Bandage Contact Lenses. J Cataract Refract Surg 2009; 35:2103–2108 Q 2009 ASCRS and ESCRS
Sirisha Senthil - One of the best experts on this subject based on the ideXlab platform.
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intermediate term outcomes of early posttrabeculectomy bleb leaks managed by large diameter soft Bandage Contact Lens
Journal of Glaucoma, 2017Co-Authors: Sriramani Gollakota, Chandra S. Garudadri, Ashik Mohamed, Sirisha SenthilAbstract:PURPOSE To study the outcomes of large diameter soft Bandage Contact Lens (BCL) in managing early trabeculectomy bleb leak. MATERIALS AND METHODS Of 972 eyes that underwent fornix-based trabeculectomy between 2011 and 2015, 19 eyes with bleb leak with at least 1 year follow-up were eligible. Bleb leak was conservatively managed using large diameter BCL (≥15.5 mm in diameter). Success was defined as complete, if bleb leak resolved and the intraocular pressure (IOP) was ≥5 and ≤18 mm Hg with no additional antiglaucoma medication and failure if surgical intervention was needed. RESULTS Mean age (±SD) of subjects was 43.5±11.9 years. Mitomycin C was used in 15/19 eyes. Median time (interquartile range) from trabeculectomy to bleb leak was 9 days (interquartile range: 8 to 19 d). Bleb leak was treated with 15.5 mm BCL in 16 eyes and 17 mm Lens in 3 eyes. Bleb leak resolved with BCL in 17 [89.5%; 95% confidence interval (95% CI), 68.6-97] and 2 eyes (10.5%; 95% CI, 2-31) required bleb resuturing. Mean duration of BCL wear for bleb leak resolution was 23.7±8.9 days. Mean IOP increased from 5.8±2.7 to 12.5±3.1 mm Hg after resolution of bleb leak (P<0.05). At 16 months, complete success probability of trabeculectomy was 89.4% (95% CI, 75.6%-100%). CONCLUSIONS Large diameter BCL was effective in the management of early bleb leak with good intermediate term success for IOP control. We suggest a trial of soft Contact Lens of appropriate diameter to manage early bleb leaks, before planning any invasive intervention.
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Intermediate Term Outcomes of Early Posttrabeculectomy Bleb Leaks Managed by Large Diameter Soft Bandage Contact Lens.
Journal of glaucoma, 2017Co-Authors: Sriramani Gollakota, Chandra S. Garudadri, Ashik Mohamed, Sirisha SenthilAbstract:PURPOSE To study the outcomes of large diameter soft Bandage Contact Lens (BCL) in managing early trabeculectomy bleb leak. MATERIALS AND METHODS Of 972 eyes that underwent fornix-based trabeculectomy between 2011 and 2015, 19 eyes with bleb leak with at least 1 year follow-up were eligible. Bleb leak was conservatively managed using large diameter BCL (≥15.5 mm in diameter). Success was defined as complete, if bleb leak resolved and the intraocular pressure (IOP) was ≥5 and ≤18 mm Hg with no additional antiglaucoma medication and failure if surgical intervention was needed. RESULTS Mean age (±SD) of subjects was 43.5±11.9 years. Mitomycin C was used in 15/19 eyes. Median time (interquartile range) from trabeculectomy to bleb leak was 9 days (interquartile range: 8 to 19 d). Bleb leak was treated with 15.5 mm BCL in 16 eyes and 17 mm Lens in 3 eyes. Bleb leak resolved with BCL in 17 [89.5%; 95% confidence interval (95% CI), 68.6-97] and 2 eyes (10.5%; 95% CI, 2-31) required bleb resuturing. Mean duration of BCL wear for bleb leak resolution was 23.7±8.9 days. Mean IOP increased from 5.8±2.7 to 12.5±3.1 mm Hg after resolution of bleb leak (P
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Role of oral doxycycline and large diameter Bandage Contact Lens in the management of early post-trabeculectomy bleb leak
BMJ case reports, 2014Co-Authors: Turaga Kiranmaye, Chandrasekhar Garudadri, Sirisha SenthilAbstract:A 27-year-old man with juvenile open angle glaucoma and medically uncontrolled intraocular pressure (IOP) underwent a trabeculectomy with mitomycin C in his right eye. One week postoperatively, he developed ischaemic necrosis of the conjunctiva with a bleb leak. This was managed conservatively with oral doxycycline 100 mg twice daily along with a topical low-dose steroid, antibiotic and cycloplegic and a large diameter Bandage Contact Lens (BCL). There was dramatic improvement in the bleb appearance, the necrosis healed and the leak resolved. The patient had well-controlled IOP with a diffuse healthy bleb at 4 weeks, which was maintained at 2 years. This case illustrates the utility and importance of oral doxycycline in the management of early post-trabeculectomy conjunctival necrosis and the use of BCL in the management of a bleb leak. This safe and non-invasive method not only hastened the recovery but also helped in maintaining good bleb function.
Michael A Grentzelos - One of the best experts on this subject based on the ideXlab platform.
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combined topical application of a regenerative agent with a Bandage Contact Lens for the treatment of persistent epithelial defects
Cornea, 2014Co-Authors: George D Kymionis, Michael A Grentzelos, Vasilios F Diakonis, Dimitrios A Liakopoulos, Nektarios E Klados, Konstantinos I Tsoulnaras, Miltiadis K Tsilimbaris, Ioannis G PallikarisAbstract:Purpose The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a Bandage Contact Lens (BCL). Methods This is a case series. Results Three patients suffering from a PED for 4-8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4-21 days, and no side effects were noted. Conclusions The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.
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efficacy of 2 types of silicone hydrogel Bandage Contact Lenses after photorefractive keratectomy
Journal of Cataract and Refractive Surgery, 2009Co-Authors: Michael A Grentzelos, Sotiris Plainis, Nikolaos Astyrakakis, Vasilios F Diakonis, George D Kymionis, Panagiotis Kallinikos, Ioannis G PallikarisAbstract:METHODS:In this prospective study, 1eyeof patients having bilateral PRKwas randomly fittedwith a Bandage Contact Lens of lotrafilcon A (Night & Day) and the fellow eye, with a Bandage Contact Lens of lotrafilcon B (O2Optix). The patients and the examiner were masked to which Bandage Contact Lens type was in which eye. Patients were examined on the day of surgery and 1, 3, and 5 days postoperatively. Postoperative examinations included uncorrected distance visual acuity and slitlamp biomicroscopy to assess epithelial defect size. Subjective evaluation of pain and vision was recorded 1, 2, 3, and 4 days postoperatively. RESULTS: The study enrolled 44 patients (88 eyes). The mean epithelial defect size immediately after surgery was 47.0 mm 2 with both types of Bandage Contact Lenses. There was no statistically significant difference in epithelial defect size between the 2 Lenses at any postoperative visit. Three days postoperatively, reepithelialization was complete in 75.0% of eyes in the lotrafilcon A group and 72.7% of the eyes in the lotrafilcon B group. CONCLUSION: There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel Bandage Contact Lenses. J Cataract Refract Surg 2009; 35:2103–2108 Q 2009 ASCRS and ESCRS
George D Kymionis - One of the best experts on this subject based on the ideXlab platform.
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combined topical application of a regenerative agent with a Bandage Contact Lens for the treatment of persistent epithelial defects
Cornea, 2014Co-Authors: George D Kymionis, Michael A Grentzelos, Vasilios F Diakonis, Dimitrios A Liakopoulos, Nektarios E Klados, Konstantinos I Tsoulnaras, Miltiadis K Tsilimbaris, Ioannis G PallikarisAbstract:Purpose The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a Bandage Contact Lens (BCL). Methods This is a case series. Results Three patients suffering from a PED for 4-8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4-21 days, and no side effects were noted. Conclusions The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.
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efficacy of 2 types of silicone hydrogel Bandage Contact Lenses after photorefractive keratectomy
Journal of Cataract and Refractive Surgery, 2009Co-Authors: Michael A Grentzelos, Sotiris Plainis, Nikolaos Astyrakakis, Vasilios F Diakonis, George D Kymionis, Panagiotis Kallinikos, Ioannis G PallikarisAbstract:METHODS:In this prospective study, 1eyeof patients having bilateral PRKwas randomly fittedwith a Bandage Contact Lens of lotrafilcon A (Night & Day) and the fellow eye, with a Bandage Contact Lens of lotrafilcon B (O2Optix). The patients and the examiner were masked to which Bandage Contact Lens type was in which eye. Patients were examined on the day of surgery and 1, 3, and 5 days postoperatively. Postoperative examinations included uncorrected distance visual acuity and slitlamp biomicroscopy to assess epithelial defect size. Subjective evaluation of pain and vision was recorded 1, 2, 3, and 4 days postoperatively. RESULTS: The study enrolled 44 patients (88 eyes). The mean epithelial defect size immediately after surgery was 47.0 mm 2 with both types of Bandage Contact Lenses. There was no statistically significant difference in epithelial defect size between the 2 Lenses at any postoperative visit. Three days postoperatively, reepithelialization was complete in 75.0% of eyes in the lotrafilcon A group and 72.7% of the eyes in the lotrafilcon B group. CONCLUSION: There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel Bandage Contact Lenses. J Cataract Refract Surg 2009; 35:2103–2108 Q 2009 ASCRS and ESCRS
Sriramani Gollakota - One of the best experts on this subject based on the ideXlab platform.
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intermediate term outcomes of early posttrabeculectomy bleb leaks managed by large diameter soft Bandage Contact Lens
Journal of Glaucoma, 2017Co-Authors: Sriramani Gollakota, Chandra S. Garudadri, Ashik Mohamed, Sirisha SenthilAbstract:PURPOSE To study the outcomes of large diameter soft Bandage Contact Lens (BCL) in managing early trabeculectomy bleb leak. MATERIALS AND METHODS Of 972 eyes that underwent fornix-based trabeculectomy between 2011 and 2015, 19 eyes with bleb leak with at least 1 year follow-up were eligible. Bleb leak was conservatively managed using large diameter BCL (≥15.5 mm in diameter). Success was defined as complete, if bleb leak resolved and the intraocular pressure (IOP) was ≥5 and ≤18 mm Hg with no additional antiglaucoma medication and failure if surgical intervention was needed. RESULTS Mean age (±SD) of subjects was 43.5±11.9 years. Mitomycin C was used in 15/19 eyes. Median time (interquartile range) from trabeculectomy to bleb leak was 9 days (interquartile range: 8 to 19 d). Bleb leak was treated with 15.5 mm BCL in 16 eyes and 17 mm Lens in 3 eyes. Bleb leak resolved with BCL in 17 [89.5%; 95% confidence interval (95% CI), 68.6-97] and 2 eyes (10.5%; 95% CI, 2-31) required bleb resuturing. Mean duration of BCL wear for bleb leak resolution was 23.7±8.9 days. Mean IOP increased from 5.8±2.7 to 12.5±3.1 mm Hg after resolution of bleb leak (P<0.05). At 16 months, complete success probability of trabeculectomy was 89.4% (95% CI, 75.6%-100%). CONCLUSIONS Large diameter BCL was effective in the management of early bleb leak with good intermediate term success for IOP control. We suggest a trial of soft Contact Lens of appropriate diameter to manage early bleb leaks, before planning any invasive intervention.
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Intermediate Term Outcomes of Early Posttrabeculectomy Bleb Leaks Managed by Large Diameter Soft Bandage Contact Lens.
Journal of glaucoma, 2017Co-Authors: Sriramani Gollakota, Chandra S. Garudadri, Ashik Mohamed, Sirisha SenthilAbstract:PURPOSE To study the outcomes of large diameter soft Bandage Contact Lens (BCL) in managing early trabeculectomy bleb leak. MATERIALS AND METHODS Of 972 eyes that underwent fornix-based trabeculectomy between 2011 and 2015, 19 eyes with bleb leak with at least 1 year follow-up were eligible. Bleb leak was conservatively managed using large diameter BCL (≥15.5 mm in diameter). Success was defined as complete, if bleb leak resolved and the intraocular pressure (IOP) was ≥5 and ≤18 mm Hg with no additional antiglaucoma medication and failure if surgical intervention was needed. RESULTS Mean age (±SD) of subjects was 43.5±11.9 years. Mitomycin C was used in 15/19 eyes. Median time (interquartile range) from trabeculectomy to bleb leak was 9 days (interquartile range: 8 to 19 d). Bleb leak was treated with 15.5 mm BCL in 16 eyes and 17 mm Lens in 3 eyes. Bleb leak resolved with BCL in 17 [89.5%; 95% confidence interval (95% CI), 68.6-97] and 2 eyes (10.5%; 95% CI, 2-31) required bleb resuturing. Mean duration of BCL wear for bleb leak resolution was 23.7±8.9 days. Mean IOP increased from 5.8±2.7 to 12.5±3.1 mm Hg after resolution of bleb leak (P
