The Experts below are selected from a list of 858 Experts worldwide ranked by ideXlab platform
Hideji Itokawa - One of the best experts on this subject based on the ideXlab platform.
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drupangtonine a novel antileukemic alkaloid from cephalotaxus harringtonia var drupacea
ChemInform, 2010Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Drupangtonine ( 1 ), a novel Cephalotaxus alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea , and its structure has been elucidated based on spectroscopic analyses. Compound 1 strongly inhibits the growth of P-388 leukemia cells.
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ester type cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Phytochemistry, 1997Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Koichi Takeya, Yukiohitotsu Yanagi, Hideji ItokawaAbstract:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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new oxygenated cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Three oxygenated cephalotaxine ester-type alkaloids, 11α-hydroxyhomodeoxyharringtonine (1), 11β-hydroxyhomodeoxyharringtonine (2) and 11β-hydroxydeoxyharringtonine (3) were isolated from Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods including 2D NMR and CD spectra, and their antileukemic activity was evaluated using P-388 leukemia cells.
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new cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:The cytotoxic alkaloids nordeoxyharringtonine (2), homodeoxyharringtonine (3), and bishomodeoxyharringtonine (4) were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established on the basis of spectral data and chemical evidence.
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cephalotaxidine a novel dimeric alkaloid from cephalotaxus harringtonia var drupacea
Tetrahedron Letters, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Cephalotaxidine (1), a novel Cephalotaxus dimeric alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea, and its structure has been elucidated based on spectroscopic analyses. Alkaloid 1 has a unique CC bridge between the two mother skeletons which are composed of homoharrigtonine and its oxygenated congener.
Ichiro Takano - One of the best experts on this subject based on the ideXlab platform.
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drupangtonine a novel antileukemic alkaloid from cephalotaxus harringtonia var drupacea
ChemInform, 2010Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Drupangtonine ( 1 ), a novel Cephalotaxus alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea , and its structure has been elucidated based on spectroscopic analyses. Compound 1 strongly inhibits the growth of P-388 leukemia cells.
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ester type cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Phytochemistry, 1997Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Koichi Takeya, Yukiohitotsu Yanagi, Hideji ItokawaAbstract:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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new oxygenated cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Three oxygenated cephalotaxine ester-type alkaloids, 11α-hydroxyhomodeoxyharringtonine (1), 11β-hydroxyhomodeoxyharringtonine (2) and 11β-hydroxydeoxyharringtonine (3) were isolated from Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods including 2D NMR and CD spectra, and their antileukemic activity was evaluated using P-388 leukemia cells.
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new cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:The cytotoxic alkaloids nordeoxyharringtonine (2), homodeoxyharringtonine (3), and bishomodeoxyharringtonine (4) were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established on the basis of spectral data and chemical evidence.
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cephalotaxidine a novel dimeric alkaloid from cephalotaxus harringtonia var drupacea
Tetrahedron Letters, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Cephalotaxidine (1), a novel Cephalotaxus dimeric alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea, and its structure has been elucidated based on spectroscopic analyses. Alkaloid 1 has a unique CC bridge between the two mother skeletons which are composed of homoharrigtonine and its oxygenated congener.
Motohiro Nishijima - One of the best experts on this subject based on the ideXlab platform.
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drupangtonine a novel antileukemic alkaloid from cephalotaxus harringtonia var drupacea
ChemInform, 2010Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Drupangtonine ( 1 ), a novel Cephalotaxus alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea , and its structure has been elucidated based on spectroscopic analyses. Compound 1 strongly inhibits the growth of P-388 leukemia cells.
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ester type cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Phytochemistry, 1997Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Koichi Takeya, Yukiohitotsu Yanagi, Hideji ItokawaAbstract:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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new oxygenated cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Three oxygenated cephalotaxine ester-type alkaloids, 11α-hydroxyhomodeoxyharringtonine (1), 11β-hydroxyhomodeoxyharringtonine (2) and 11β-hydroxydeoxyharringtonine (3) were isolated from Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods including 2D NMR and CD spectra, and their antileukemic activity was evaluated using P-388 leukemia cells.
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new cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:The cytotoxic alkaloids nordeoxyharringtonine (2), homodeoxyharringtonine (3), and bishomodeoxyharringtonine (4) were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established on the basis of spectral data and chemical evidence.
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cephalotaxidine a novel dimeric alkaloid from cephalotaxus harringtonia var drupacea
Tetrahedron Letters, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Cephalotaxidine (1), a novel Cephalotaxus dimeric alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea, and its structure has been elucidated based on spectroscopic analyses. Alkaloid 1 has a unique CC bridge between the two mother skeletons which are composed of homoharrigtonine and its oxygenated congener.
Ichiro Yasuda - One of the best experts on this subject based on the ideXlab platform.
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drupangtonine a novel antileukemic alkaloid from cephalotaxus harringtonia var drupacea
ChemInform, 2010Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Drupangtonine ( 1 ), a novel Cephalotaxus alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea , and its structure has been elucidated based on spectroscopic analyses. Compound 1 strongly inhibits the growth of P-388 leukemia cells.
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ester type cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Phytochemistry, 1997Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Koichi Takeya, Yukiohitotsu Yanagi, Hideji ItokawaAbstract:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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new oxygenated cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Three oxygenated cephalotaxine ester-type alkaloids, 11α-hydroxyhomodeoxyharringtonine (1), 11β-hydroxyhomodeoxyharringtonine (2) and 11β-hydroxydeoxyharringtonine (3) were isolated from Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods including 2D NMR and CD spectra, and their antileukemic activity was evaluated using P-388 leukemia cells.
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new cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:The cytotoxic alkaloids nordeoxyharringtonine (2), homodeoxyharringtonine (3), and bishomodeoxyharringtonine (4) were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established on the basis of spectral data and chemical evidence.
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cephalotaxidine a novel dimeric alkaloid from cephalotaxus harringtonia var drupacea
Tetrahedron Letters, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Cephalotaxidine (1), a novel Cephalotaxus dimeric alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea, and its structure has been elucidated based on spectroscopic analyses. Alkaloid 1 has a unique CC bridge between the two mother skeletons which are composed of homoharrigtonine and its oxygenated congener.
Koichi Takeya - One of the best experts on this subject based on the ideXlab platform.
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drupangtonine a novel antileukemic alkaloid from cephalotaxus harringtonia var drupacea
ChemInform, 2010Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Drupangtonine ( 1 ), a novel Cephalotaxus alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea , and its structure has been elucidated based on spectroscopic analyses. Compound 1 strongly inhibits the growth of P-388 leukemia cells.
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ester type cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Phytochemistry, 1997Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Koichi Takeya, Yukiohitotsu Yanagi, Hideji ItokawaAbstract:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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new oxygenated cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Three oxygenated cephalotaxine ester-type alkaloids, 11α-hydroxyhomodeoxyharringtonine (1), 11β-hydroxyhomodeoxyharringtonine (2) and 11β-hydroxydeoxyharringtonine (3) were isolated from Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods including 2D NMR and CD spectra, and their antileukemic activity was evaluated using P-388 leukemia cells.
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new cephalotaxus alkaloids from cephalotaxus harringtonia var drupacea
Journal of Natural Products, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:The cytotoxic alkaloids nordeoxyharringtonine (2), homodeoxyharringtonine (3), and bishomodeoxyharringtonine (4) were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established on the basis of spectral data and chemical evidence.
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cephalotaxidine a novel dimeric alkaloid from cephalotaxus harringtonia var drupacea
Tetrahedron Letters, 1996Co-Authors: Ichiro Takano, Ichiro Yasuda, Motohiro Nishijima, Yukio Hitotsuyanagi, Koichi Takeya, Hideji ItokawaAbstract:Abstract Cephalotaxidine (1), a novel Cephalotaxus dimeric alkaloid, has been isolated from Cephalotaxus harringtonia var. drupacea, and its structure has been elucidated based on spectroscopic analyses. Alkaloid 1 has a unique CC bridge between the two mother skeletons which are composed of homoharrigtonine and its oxygenated congener.
