The Experts below are selected from a list of 189 Experts worldwide ranked by ideXlab platform
Azam Vafaie - One of the best experts on this subject based on the ideXlab platform.
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sensitized spectrophotometric determination of cr iii ion for speciation of chromium ion in surfactant media using α benzoin oxime
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2006Co-Authors: Mehrorang Ghaedi, Enayat Asadpour, Azam VafaieAbstract:Abstract A simple and accurate micellanized spectrophotometric method for determination of trace amounts of Cr(III) ion in tab and top water and a synthetic mixture has been described. The micellar method is based on effect of organized molecular assemblies such as micelles in spectrophotometric measurement due to their effect on the systems of interest. The ability of micellar system in solubilizing of sparingly soluble ligand or complexes has been used for increasing figures of merit of an analytical method. Due to solubility increasing in aqueous media requirement for a primary extraction can be eliminated. Using the α-benzoin oxime (α-BO) spectrophotometric determination of Cr(III) ion has been performed and results are compared. The spectrophotometric determination of Cr(III) ion using α-BO in the presence of non-ionic surfactant Triton X-100 has been performed. The influence of type and amount of surfactant, pH, complexation time and amount of ligand were examined. Finally, the repeatability, accuracy and the effect of interfering ions on the determination of Cr(III) ion was evaluated. The proposed methods successfully with recovery yield of almost 100% have been applied to the rapid and simple determination of Cr(III) ion in the real samples. There is a good agreement between methods and atomic absorption spectrometry. The Beers Law is obeyed over the concentration range of 0.1–13.7 μg mL −1 for micellar media. The detection limit is 0.8 ng mL −1 . The molar absorptivity of complex is 5350 L mol −1 cm −1 .
D Jothieswari - One of the best experts on this subject based on the ideXlab platform.
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Development and Validation of a UV Spectrophotometric Method for the Simultaneous Estimation of Eprosartan Mesylate and Hydrochlorothiazide in Bulk and Formulations.
Indian Journal of Pharmaceutical Sciences, 2011Co-Authors: K Anandakumar, D Vijaya Santhi, D Jothieswari, R Subathrai, T. VetrichelvanAbstract:A simple, efficient, precise and accurate absorbance ratio method have been developed for the estimation of eprosartan mesylate and hydrochlorothiazide in pure and in fixed dose combination. In this method, UV spectra of eprosartan mesylate and hydrochlorothiazide were overlayed which involves the formation of Q-absorbance equation at 249.1 nm (isobestic point) and 274.5 nm, the max of hydrochlorothiazide. Both the drugs obeyed Beers Law in the concentration range of 6-36 μg/ml and 1-10 μg/ml for eprosartan mesylate and hydrochlorothiazide, respectively. The accuracy of the method was determined by recovery studies and was found to be in the range of 102.29-103.10% and 99.52-101.60% for eprosartan mesylate and hydrochlorothiazide, respectively. The method was validated as per ICH guidelines and statistically. The method showed good reproducibility and recovery with % RSD less than 2. The method was found to be simple, economic, accurate and reproducible and can be used for routine analysis of eprosartan mesylate and hydrochlorothiazide in pure and in fixed dose combinations.
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A Novel Estimation of Eprosartan Mesylate in Pure and in Tablet Formulations by Simple UV Method
Research Journal of Pharmacy and Technology, 2011Co-Authors: D Vijaya Santhi, Nallagundla H. S. Reddy, N Sumalatha, D JothieswariAbstract:A simple efficient, precise and accurate simple UV method have been developed for the estimation of Eprosartan Mesylate in pure and in pharmaceutical tablet dosage forms. In this method UV Spectra of Eprosartan Mesylate in 0.1M Sodium Hydroxide acid exhibits the absorption maximum 292 nm. Beers Law limits the concentration range of 5 -25 μg/ml for this method. The accuracy of the method was determined by recovery studies. This method was validated statistically. This method showed good reproducibility and recovery with % RSD less than 2. This method was found to be simple, economical, accurate and reproducible and can be used for routine analysis of Eprosartan Mesylate in pure drug and in tablet formulations.
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A Novel Estimation of Eprosartan Mesylate in Pure and in Tablet Formulations by Simple UV Method
Research Journal of Pharmacy and Technology, 2011Co-Authors: D Vijaya Santhi, Nallagundla H. S. Reddy, N Sumalatha, D JothieswariAbstract:A simple efficient, precise and accurate simple UV method have been developed for the estimation of Eprosartan Mesylate in pure and in pharmaceutical tablet dosage forms. In this method UV Spectra of Eprosartan Mesylate in 0.1M Sodium Hydroxide acid exhibits the absorption maximum 292 nm. Beers Law limits the concentration range of 5 -25 μg/ml for this method. The accuracy of the method was determined by recovery studies. This method was validated statistically. This method showed good reproducibility and recovery with % RSD less than 2. This method was found to be simple, economical, accurate and reproducible and can be used for routine analysis of Eprosartan Mesylate in pure drug and in tablet formulations.
A V Kasture - One of the best experts on this subject based on the ideXlab platform.
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simultaneous estimation of cinitapride hydrogen tartrate cnt and pantoprazole sodium sesquihydrate pnp in capsule by q analysis uv spectrophotometric method
Asian Journal of Research in Chemistry, 2013Co-Authors: N R Dighade, M D Shende, A V KastureAbstract:Cinitapride and Pantoprazole are available as capsule dosage forms in the ratio 1:13.33. A simple reproducible and efficient method for the simultaneous determination of cinitapride and pantoprazole in marketed formulation was developed. The proposed method is based on the Q-analysis UV-Spectrophotometric method. The absorbance maximum of cinitapride and pantoprazole were found to be 265.5 nm and 268 nm respectively in water. In Q-analysis, the isoabsorptive point for both the drugs was found at 236 nm. The linearity range lies between 5–30 μg/ml for cinitapride and pantoprazole at their respective wavelengths. Both the drugs obey Beers Law. The recovery studies confirmed the accuracy of the proposed method.
D Vijaya Santhi - One of the best experts on this subject based on the ideXlab platform.
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Development and Validation of a UV Spectrophotometric Method for the Simultaneous Estimation of Eprosartan Mesylate and Hydrochlorothiazide in Bulk and Formulations.
Indian Journal of Pharmaceutical Sciences, 2011Co-Authors: K Anandakumar, D Vijaya Santhi, D Jothieswari, R Subathrai, T. VetrichelvanAbstract:A simple, efficient, precise and accurate absorbance ratio method have been developed for the estimation of eprosartan mesylate and hydrochlorothiazide in pure and in fixed dose combination. In this method, UV spectra of eprosartan mesylate and hydrochlorothiazide were overlayed which involves the formation of Q-absorbance equation at 249.1 nm (isobestic point) and 274.5 nm, the max of hydrochlorothiazide. Both the drugs obeyed Beers Law in the concentration range of 6-36 μg/ml and 1-10 μg/ml for eprosartan mesylate and hydrochlorothiazide, respectively. The accuracy of the method was determined by recovery studies and was found to be in the range of 102.29-103.10% and 99.52-101.60% for eprosartan mesylate and hydrochlorothiazide, respectively. The method was validated as per ICH guidelines and statistically. The method showed good reproducibility and recovery with % RSD less than 2. The method was found to be simple, economic, accurate and reproducible and can be used for routine analysis of eprosartan mesylate and hydrochlorothiazide in pure and in fixed dose combinations.
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A Novel Estimation of Eprosartan Mesylate in Pure and in Tablet Formulations by Simple UV Method
Research Journal of Pharmacy and Technology, 2011Co-Authors: D Vijaya Santhi, Nallagundla H. S. Reddy, N Sumalatha, D JothieswariAbstract:A simple efficient, precise and accurate simple UV method have been developed for the estimation of Eprosartan Mesylate in pure and in pharmaceutical tablet dosage forms. In this method UV Spectra of Eprosartan Mesylate in 0.1M Sodium Hydroxide acid exhibits the absorption maximum 292 nm. Beers Law limits the concentration range of 5 -25 μg/ml for this method. The accuracy of the method was determined by recovery studies. This method was validated statistically. This method showed good reproducibility and recovery with % RSD less than 2. This method was found to be simple, economical, accurate and reproducible and can be used for routine analysis of Eprosartan Mesylate in pure drug and in tablet formulations.
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A Novel Estimation of Eprosartan Mesylate in Pure and in Tablet Formulations by Simple UV Method
Research Journal of Pharmacy and Technology, 2011Co-Authors: D Vijaya Santhi, Nallagundla H. S. Reddy, N Sumalatha, D JothieswariAbstract:A simple efficient, precise and accurate simple UV method have been developed for the estimation of Eprosartan Mesylate in pure and in pharmaceutical tablet dosage forms. In this method UV Spectra of Eprosartan Mesylate in 0.1M Sodium Hydroxide acid exhibits the absorption maximum 292 nm. Beers Law limits the concentration range of 5 -25 μg/ml for this method. The accuracy of the method was determined by recovery studies. This method was validated statistically. This method showed good reproducibility and recovery with % RSD less than 2. This method was found to be simple, economical, accurate and reproducible and can be used for routine analysis of Eprosartan Mesylate in pure drug and in tablet formulations.
Mehrorang Ghaedi - One of the best experts on this subject based on the ideXlab platform.
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sensitized spectrophotometric determination of cr iii ion for speciation of chromium ion in surfactant media using α benzoin oxime
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2006Co-Authors: Mehrorang Ghaedi, Enayat Asadpour, Azam VafaieAbstract:Abstract A simple and accurate micellanized spectrophotometric method for determination of trace amounts of Cr(III) ion in tab and top water and a synthetic mixture has been described. The micellar method is based on effect of organized molecular assemblies such as micelles in spectrophotometric measurement due to their effect on the systems of interest. The ability of micellar system in solubilizing of sparingly soluble ligand or complexes has been used for increasing figures of merit of an analytical method. Due to solubility increasing in aqueous media requirement for a primary extraction can be eliminated. Using the α-benzoin oxime (α-BO) spectrophotometric determination of Cr(III) ion has been performed and results are compared. The spectrophotometric determination of Cr(III) ion using α-BO in the presence of non-ionic surfactant Triton X-100 has been performed. The influence of type and amount of surfactant, pH, complexation time and amount of ligand were examined. Finally, the repeatability, accuracy and the effect of interfering ions on the determination of Cr(III) ion was evaluated. The proposed methods successfully with recovery yield of almost 100% have been applied to the rapid and simple determination of Cr(III) ion in the real samples. There is a good agreement between methods and atomic absorption spectrometry. The Beers Law is obeyed over the concentration range of 0.1–13.7 μg mL −1 for micellar media. The detection limit is 0.8 ng mL −1 . The molar absorptivity of complex is 5350 L mol −1 cm −1 .