The Experts below are selected from a list of 72 Experts worldwide ranked by ideXlab platform
Jiang Yiqiang - One of the best experts on this subject based on the ideXlab platform.
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effects of pretreatment with adrenalectomy and Benadryl injection on pulmonary edema in rats after head trauma
Chinese critical care medicine, 1999Co-Authors: Jiang YiqiangAbstract:Objective:To investigate the potential mechanism(s) concerning neurogenic pulmonary edema (NPE) after trauma.Methods:A NPE model was produced by inflicting head trauma to rats.The effects of pretreatment with general anesthesia (GA) and false operation on adrenal (GA+FO),GA and adrenalectomy (GA+A),and GA and adrenalectomy together with Benadryl injection intravenously (GA+A+B) on pulmonary pathological changes were studied in rats after head trauma.Results:It showed that the pulmonary edema and hemorrhage in both GA+FO and GA+A groups were much more severe than in normal control and GA+A+B groups.However,the pulmonary changes in GA+A+B group were mild and similar to those in normal controls.Conclusions:These results suggest that pretreatment with adrenalectomy and Benadryl injection but not single adrenalectomy can markedly prevent head injuryinduced pulmonary edema and hemorrhage,and histamine might play an important role in the pathogenesis of NPE.
Stephen A Tilles - One of the best experts on this subject based on the ideXlab platform.
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approach to therapy in chronic urticaria when Benadryl is not enough
Allergy and Asthma Proceedings, 2005Co-Authors: Stephen A TillesAbstract:Chronic urticaria is a relatively common disorder in which its management often presents a difficult clinical challenge. Histamine antagonists are the mainstays of therapy, and the second-generation antihistamines offer an attractive combination of efficacy, convenience, and lack of side effects. For patients whose symptoms are not controlled by once daily second-generation antihistamines, adjunct therapy with first generation H 1 -antihistamines, H 2 -antihistamines, doxepin, or leukotriene modifiers may be effective. Short-term systemic corticosteroids are useful for acute symptom flares but should not be used chronically. For chronically unremitting disease, immunomodiilatory agents such as low-dose oral cyclosporine often are useful.
Hong Jiang - One of the best experts on this subject based on the ideXlab platform.
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clinical efficacy of Benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
Chinese Journal of Medical Aesthetics and Cosmetology, 2009Co-Authors: Q I Yuqing, Guizhi Zhang, Hong JiangAbstract:Objective To assess the clinical efficacy and safety of 1% Benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% Benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P<0.05). Conclusions 1% Benadryl and 3 % metronidazle cream are effective and safe in the treatment of topical torticosteroid dependent dermatitis. Key words: Benadryl cream; Metronidazle cream; Topical corticosteroid dependent dermatitis
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Clinical efficacy of Benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
Chinese Journal of Medical Aesthetics and Cosmetology, 2009Co-Authors: Yu-qing Qi, Guizhi Zhang, Hong JiangAbstract:Objective To assess the clinical efficacy and safety of 1% Benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% Benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P
Daniel Berman - One of the best experts on this subject based on the ideXlab platform.
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local prophylactic Benadryl injections in an attempt to reduce postinstrumental pain
Journal of Endodontics, 1994Co-Authors: Alan Nevins, Robert Verhelle, Michael J Feldman, Daniel BermanAbstract:This study was done to determine the clinical efficacy of a 15-mg diphenhydremine hydrochloride (Benadryl) local injection as a prophylactic treatment in the prevention of pain resulting from initial instrumentation of necrotic teeth. A double-blind study comprised of 37 subjects, each with one nonvital maxillary tooth, was completed in which patients were divided into two equal groups. The experimental group received a local anesthetic of 3% Carbocaine, followed by an additional injection of the antihistamine. The control group received the local anesthetic and an equivalent quantity of sterile saline. Patients recorded their pain levels at various time intervals: preoperatively, immediately postoperatively, and at 3, 7, 12, and 24 h postoperatively. Graphic analysis using a Quatro-Pro spread sheet program showed that there were no significant differences between the groups pain scores. However, there was a correlation between pain and time elapsed after procedure. In both groups, postoperative pain appeared to increase from 3 to 7 h and decrease from 7 to 24 h.
Guizhi Zhang - One of the best experts on this subject based on the ideXlab platform.
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clinical efficacy of Benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
Chinese Journal of Medical Aesthetics and Cosmetology, 2009Co-Authors: Q I Yuqing, Guizhi Zhang, Hong JiangAbstract:Objective To assess the clinical efficacy and safety of 1% Benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% Benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P<0.05). Conclusions 1% Benadryl and 3 % metronidazle cream are effective and safe in the treatment of topical torticosteroid dependent dermatitis. Key words: Benadryl cream; Metronidazle cream; Topical corticosteroid dependent dermatitis
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Clinical efficacy of Benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
Chinese Journal of Medical Aesthetics and Cosmetology, 2009Co-Authors: Yu-qing Qi, Guizhi Zhang, Hong JiangAbstract:Objective To assess the clinical efficacy and safety of 1% Benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% Benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P
