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Li Zhang - One of the best experts on this subject based on the ideXlab platform.
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Two Mononuclear Iron(II) Spin-Crossover Complexes with a N4O2 Coordination Sphere
欧洲无机化学杂志, 2013Co-Authors: Li Zhang, Xu Guan-cheng, Wang Zhe-ming, Gao SongAbstract:Two mononuclear spin-crossover compounds Fe(L-1)(2) (1) and Fe(L-2)(2) (2) {HL1 = 2-hydroxy-3-methyl-N'-[1-(pyridine-2-yl)-butylidene]Benzohydrazide, HL2 = 2-hydroxy-N'-[1-(pyridine-2-yl)butylidene]Benzohydrazide} were successfully synthesized. The magnetic measurements of the compounds revealed different thermal magnetic behavior. Compound 1 undergoes a gradual complete thermal spin crossover (SCO) with T-1/2 up arrow/down arrow = 243/240 K and a hysteresis loop of 3 K. Compound 2 shows a gradual incomplete SCO during the measurable temperature region with T-1/2 approximate to 330 K. Through the comparison of the magnetic and structural results for 1 and 2 with previously reported related compounds, the alkyl substitutions of the ligand were considered to affect the ligand-field strength and hydrogen-bonding interactions. In addition, photomagnetism results showed an 87 % photoconversion and 36 K of T(LIESST) (LIESST = light-induced excited spin-state trapping) for compound 1. The results enrich the knowledge on how to control the spin-crossover behavior in the new system.Chemistry, Inorganic & NuclearSCI(E)1ARTICLE5-6,SI1043-104
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synthesis magnetic and photomagnetic study of new iron ii spin crossover complexes with n4o2 coordination sphere
Dalton Transactions, 2010Co-Authors: Li Zhang, Valeriu Mereacre, Zheming Wang, Annie K Powell, Song GaoAbstract:A new family of neutral mononuclear iron(II) spin crossover (SCO) compounds, Fe(L1–6)2 (L1–6 = N′-((pyridin-2-yl)methylene)Benzohydrazide (HL1), N′-(1-(pyridin-2-yl)ethylidene)-Benzohydrazide (HL2), N′-(phenyl(pyridin-2-yl)methylene)Benzohydrazide (HL3), 2-hydroxy-N′-((pyridin-2-yl)methylene)Benzohydrazide (HL4), 2-hydroxy-N′-(1-(pyridin-2-yl)ethylidene)Benzohydrazide (HL5), 2-hydroxy-N′-(phenyl(pyridin-2-yl)methylene)Benzohydrazide (HL6)) with N4O2 donor sets have been synthesized from series tridentate Schiff base ligands with N,N,O donor sets. The investigation of magnetic properties of these compounds reveal that in the measured temperature range, compound 1 is in the high-spin (HS) state, and compound 3 and 6 are mainly in the low-spin (LS) state, whereas the other compounds exhibit various SCO properties: compound 2 undergoes a gradual incomplete SCO with characteristic temperature T1/2 higher than 350 K; compound 4 exhibits a special stepwise thermally induced SCO occurring at ∼150 K (smooth) and 200 K (two-steps, with TS1↑/↓ = 204/202 K and TS2↑/↓ = 227/219 K) with a mixture of the HS and LS states yielded below 100 K; compound 5 shows a gradual and complete LS ↔ HS SCO with characteristic temperature T1/2 = 273 K. All the three SCO compounds show the LIESST (light induced exited spin state trapping) effect with different levels of photoconversion. To thoroughly analyze these behaviours, Mossbauer spectra and DSC of 4 and 5, crystal structures of all the compounds at 290 K and 5 in the LS state at 110 K were carried out, which confirmed the structural changes accompanying the spin transition. In addition, alkyl substitution effect on the ligand field was suggested for this system.
Ray J Butcher - One of the best experts on this subject based on the ideXlab platform.
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synthesis crystal structure and dft calculations of octahedral nickel ii complexes derived from n e phenyl pyridin 2 yl methylidene Benzohydrazide
Journal of Coordination Chemistry, 2016Co-Authors: Ram N Patel, Yogendra Singh, Ray J ButcherAbstract:AbstractThe two new nickel(II) complexes, [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) (where HL/L = N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide), have been synthesized and characterized by elemental analysis, spectroscopic, magnetic susceptibility, and cyclic voltammetric measurements. Single-crystal X-ray analysis of [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) has revealed the presence of a distorted octahedral geometry around nickel(II). The X-ray and spectral characterizations have confirmed the existence of the keto-enol form of the ligands in the complexes. The electronic structures and spectral properties of the ligands and the complexes have been explained by DFT and TDDFT calculations. Superoxide dismutase activity of these complexes has also been measured.
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Synthesis, crystal structure and DFT calculations of octahedral nickel(II) complexes derived from N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide
2016Co-Authors: Ram N Patel, Yogendra Singh, Yogendra Pratap Singh, Ray J ButcherAbstract:The two new nickel(II) complexes, [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) (where HL/L = N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide), have been synthesized and characterized by elemental analysis, spectroscopic, magnetic susceptibility, and cyclic voltammetric measurements. Single-crystal X-ray analysis of [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) has revealed the presence of a distorted octahedral geometry around nickel(II). The X-ray and spectral characterizations have confirmed the existence of the keto-enol form of the ligands in the complexes. The electronic structures and spectral properties of the ligands and the complexes have been explained by DFT and TDDFT calculations. Superoxide dismutase activity of these complexes has also been measured.
Yogendra Singh - One of the best experts on this subject based on the ideXlab platform.
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synthesis crystal structure and dft calculations of octahedral nickel ii complexes derived from n e phenyl pyridin 2 yl methylidene Benzohydrazide
Journal of Coordination Chemistry, 2016Co-Authors: Ram N Patel, Yogendra Singh, Ray J ButcherAbstract:AbstractThe two new nickel(II) complexes, [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) (where HL/L = N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide), have been synthesized and characterized by elemental analysis, spectroscopic, magnetic susceptibility, and cyclic voltammetric measurements. Single-crystal X-ray analysis of [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) has revealed the presence of a distorted octahedral geometry around nickel(II). The X-ray and spectral characterizations have confirmed the existence of the keto-enol form of the ligands in the complexes. The electronic structures and spectral properties of the ligands and the complexes have been explained by DFT and TDDFT calculations. Superoxide dismutase activity of these complexes has also been measured.
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Synthesis, crystal structure and DFT calculations of octahedral nickel(II) complexes derived from N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide
2016Co-Authors: Ram N Patel, Yogendra Singh, Yogendra Pratap Singh, Ray J ButcherAbstract:The two new nickel(II) complexes, [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) (where HL/L = N′-[(E)-phenyl(pyridin-2-yl)methylidene]Benzohydrazide), have been synthesized and characterized by elemental analysis, spectroscopic, magnetic susceptibility, and cyclic voltammetric measurements. Single-crystal X-ray analysis of [Ni(HL)(L)](NO3)∙H2O (1) and [Ni(L)2] (2) has revealed the presence of a distorted octahedral geometry around nickel(II). The X-ray and spectral characterizations have confirmed the existence of the keto-enol form of the ligands in the complexes. The electronic structures and spectral properties of the ligands and the complexes have been explained by DFT and TDDFT calculations. Superoxide dismutase activity of these complexes has also been measured.
Souhir Abid - One of the best experts on this subject based on the ideXlab platform.
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(E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)Benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests
European Journal of Pharmacology, 2020Co-Authors: Khdhiri Emna, Kais Mnafgui, Lakhdar Ghazouani, Anouar Feriani, Raouf Hajji, Walid Bouzanna, Noureddine Allouche, Jean-pierre Bazureau, Houcine Ammar, Souhir AbidAbstract:The current study was aimed to assess the protective effect of a new molecule (E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)Benzohydrazide, denoted 1c, against cardiac remodeling process in isoproterenol (Isop) induced myocardial infarction (MI) in rats. Male Wistar rats were randomly divided into four groups, control, Isop (85 mg/kg body weight was injected subcutaneously into rats at an interval of 24 h for 2 days (6 and 7 day) to induce MI and pretreated animals with acenocoumarol (Ace) (150 μg/kg bw) and 1c (150 μg/kg bw) by oral administration during 7 days and injected with isoproterenol (Isop + Ace) and (Isop + 1c) groups. Results in vitro showed that 1c is endowed with potent inhibition of angiotensin-converting enzyme (ACE) with an IC 39.12 μg/ml. The in vivo exploration evidenced alteration in the ECG pattern, notable cardiac hypertrophy and increase in plasma level of fibrinogen, troponin-T, CK-MB and LDH, AST and ALT by 171%, 300%, 50%, 64% and 75% respectively with histological myocardium necrosis and cells inflammatory infiltration. However, pre-treatment with 1c improved the ECG pattern reduced significantly the cardiac dysfunction markers and ameliorated the thrombolytic process by decreasing fibrinogen level as compared to untreated infracted rats. Overall, (E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)Benzohydrazide 1c could be used as anticoagulant agent to prevent thrombosis in acute myocardial infarction.
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anti embolic and anti oxidative effects of a novel e 4 amino n 1 7 hydroxy 2 oxo 2h chromen 3 yl ethylidene Benzohydrazide against isoproterenol and vitamin k induced ischemic stroke
Archives of Physiology and Biochemistry, 2019Co-Authors: Kais Mnafgui, Lakhdar Ghazouani, Noureddine Allouche, Houcine Ammar, Souhir Abid, Emna Khdhiri, Marwa Ncir, Zouhaier Zaafouri, Abdelfattah ElfekiAbstract:This study aimed to evaluate the cerebroprotective potential of a novel synthetic coumarin, (E)-4-amino-N′-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl)ethylidene) Benzohydrazide noted (HC) against a pharma...
Song Gao - One of the best experts on this subject based on the ideXlab platform.
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synthesis magnetic and photomagnetic study of new iron ii spin crossover complexes with n4o2 coordination sphere
Dalton Transactions, 2010Co-Authors: Li Zhang, Valeriu Mereacre, Zheming Wang, Annie K Powell, Song GaoAbstract:A new family of neutral mononuclear iron(II) spin crossover (SCO) compounds, Fe(L1–6)2 (L1–6 = N′-((pyridin-2-yl)methylene)Benzohydrazide (HL1), N′-(1-(pyridin-2-yl)ethylidene)-Benzohydrazide (HL2), N′-(phenyl(pyridin-2-yl)methylene)Benzohydrazide (HL3), 2-hydroxy-N′-((pyridin-2-yl)methylene)Benzohydrazide (HL4), 2-hydroxy-N′-(1-(pyridin-2-yl)ethylidene)Benzohydrazide (HL5), 2-hydroxy-N′-(phenyl(pyridin-2-yl)methylene)Benzohydrazide (HL6)) with N4O2 donor sets have been synthesized from series tridentate Schiff base ligands with N,N,O donor sets. The investigation of magnetic properties of these compounds reveal that in the measured temperature range, compound 1 is in the high-spin (HS) state, and compound 3 and 6 are mainly in the low-spin (LS) state, whereas the other compounds exhibit various SCO properties: compound 2 undergoes a gradual incomplete SCO with characteristic temperature T1/2 higher than 350 K; compound 4 exhibits a special stepwise thermally induced SCO occurring at ∼150 K (smooth) and 200 K (two-steps, with TS1↑/↓ = 204/202 K and TS2↑/↓ = 227/219 K) with a mixture of the HS and LS states yielded below 100 K; compound 5 shows a gradual and complete LS ↔ HS SCO with characteristic temperature T1/2 = 273 K. All the three SCO compounds show the LIESST (light induced exited spin state trapping) effect with different levels of photoconversion. To thoroughly analyze these behaviours, Mossbauer spectra and DSC of 4 and 5, crystal structures of all the compounds at 290 K and 5 in the LS state at 110 K were carried out, which confirmed the structural changes accompanying the spin transition. In addition, alkyl substitution effect on the ligand field was suggested for this system.