The Experts below are selected from a list of 228 Experts worldwide ranked by ideXlab platform
Claire Richard - One of the best experts on this subject based on the ideXlab platform.
-
sulfate radical induced degradation of β2 adrenoceptor agonists salbutamol and terbutaline phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, Pascal De Sainteclaire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Degradation of β2-adrenoceptor agonists salbutamol and terbutaline by UV-activated persulfate
2017Co-Authors: L. Zhou, C. Ferronato, J. Chovelon, M. Sleiman, Claire RichardAbstract:This work investigated the degradation reactivity and mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists by using persulfate (PS) activated bysimulated solar light. Our results indicated that UV/PS could remove these two target compounds efficiently, more than 94% of SAL and TBL could be decomposed within 2h. The quenching experiment suggested that SO4•− was the dominant reactive species in the oxidation process. The second-order rate constant of sulfate radical with SAL and TBL was calculated as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M-1 s-1 by using laser flasher photolysis (LFP), respectively. The results also revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. Reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, LFP and molecular orbital calculations. For both of the target compounds, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, the transformation of the phenoxyl radical into benzoquinone was impossible for TBL. Instead, the addition of –OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. The present work indicated that UV/PS oxidation method could be a promising approach in the removal of β2-adrenoceptor agonists and related pharmaceuticals. Moreover, it could also help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Sulfate radical induced degradation of beta 2-adrenoceptor agonists salbutamol and terbutaline: Phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, P De Sainte-claire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
M. Sleiman - One of the best experts on this subject based on the ideXlab platform.
-
sulfate radical induced degradation of β2 adrenoceptor agonists salbutamol and terbutaline phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, Pascal De Sainteclaire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Degradation of β2-adrenoceptor agonists salbutamol and terbutaline by UV-activated persulfate
2017Co-Authors: L. Zhou, C. Ferronato, J. Chovelon, M. Sleiman, Claire RichardAbstract:This work investigated the degradation reactivity and mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists by using persulfate (PS) activated bysimulated solar light. Our results indicated that UV/PS could remove these two target compounds efficiently, more than 94% of SAL and TBL could be decomposed within 2h. The quenching experiment suggested that SO4•− was the dominant reactive species in the oxidation process. The second-order rate constant of sulfate radical with SAL and TBL was calculated as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M-1 s-1 by using laser flasher photolysis (LFP), respectively. The results also revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. Reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, LFP and molecular orbital calculations. For both of the target compounds, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, the transformation of the phenoxyl radical into benzoquinone was impossible for TBL. Instead, the addition of –OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. The present work indicated that UV/PS oxidation method could be a promising approach in the removal of β2-adrenoceptor agonists and related pharmaceuticals. Moreover, it could also help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Sulfate radical induced degradation of beta 2-adrenoceptor agonists salbutamol and terbutaline: Phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, P De Sainte-claire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
J. Chovelon - One of the best experts on this subject based on the ideXlab platform.
-
sulfate radical induced degradation of β2 adrenoceptor agonists salbutamol and terbutaline phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, Pascal De Sainteclaire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Degradation of β2-adrenoceptor agonists salbutamol and terbutaline by UV-activated persulfate
2017Co-Authors: L. Zhou, C. Ferronato, J. Chovelon, M. Sleiman, Claire RichardAbstract:This work investigated the degradation reactivity and mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists by using persulfate (PS) activated bysimulated solar light. Our results indicated that UV/PS could remove these two target compounds efficiently, more than 94% of SAL and TBL could be decomposed within 2h. The quenching experiment suggested that SO4•− was the dominant reactive species in the oxidation process. The second-order rate constant of sulfate radical with SAL and TBL was calculated as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M-1 s-1 by using laser flasher photolysis (LFP), respectively. The results also revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. Reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, LFP and molecular orbital calculations. For both of the target compounds, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, the transformation of the phenoxyl radical into benzoquinone was impossible for TBL. Instead, the addition of –OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. The present work indicated that UV/PS oxidation method could be a promising approach in the removal of β2-adrenoceptor agonists and related pharmaceuticals. Moreover, it could also help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Sulfate radical induced degradation of beta 2-adrenoceptor agonists salbutamol and terbutaline: Phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, P De Sainte-claire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
C. Ferronato - One of the best experts on this subject based on the ideXlab platform.
-
sulfate radical induced degradation of β2 adrenoceptor agonists salbutamol and terbutaline phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, Pascal De Sainteclaire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Degradation of β2-adrenoceptor agonists salbutamol and terbutaline by UV-activated persulfate
2017Co-Authors: L. Zhou, C. Ferronato, J. Chovelon, M. Sleiman, Claire RichardAbstract:This work investigated the degradation reactivity and mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists by using persulfate (PS) activated bysimulated solar light. Our results indicated that UV/PS could remove these two target compounds efficiently, more than 94% of SAL and TBL could be decomposed within 2h. The quenching experiment suggested that SO4•− was the dominant reactive species in the oxidation process. The second-order rate constant of sulfate radical with SAL and TBL was calculated as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M-1 s-1 by using laser flasher photolysis (LFP), respectively. The results also revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. Reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, LFP and molecular orbital calculations. For both of the target compounds, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, the transformation of the phenoxyl radical into benzoquinone was impossible for TBL. Instead, the addition of –OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. The present work indicated that UV/PS oxidation method could be a promising approach in the removal of β2-adrenoceptor agonists and related pharmaceuticals. Moreover, it could also help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
-
Sulfate radical induced degradation of beta 2-adrenoceptor agonists salbutamol and terbutaline: Phenoxyl radical dependent mechanisms
Water Research, 2017Co-Authors: M. Sleiman, C. Ferronato, J. Chovelon, P De Sainte-claire, Claire RichardAbstract:The present study investigated the reactivity and oxidation mechanisms of salbutamol (SAL) and terbutaline (TBL), two typical β2-adrenoceptor agonists, towards sulfate radical (SO4−) by using photo-activated persulfate (PS). The reaction pathways and mechanisms were proposed based on products identification using high resolution HPLC-ESI-MS, laser flash photolysis (LFP) and molecular orbital calculations. The results indicated that SO4− was the dominant reactive species in the UV/PS process. The second-order rate constants of sulfate radical reaction with SAL and TBL were measured as (3.7 ± 0.3) × 109 and (4.2 ± 0.3) × 109 M−1 s−1 by LFP, respectively. For both SAL and TBL, phenoxyl radicals were found to play key roles in the orientation of the primary pathways. For SAL, a Benzophenone Derivative was generated by oxidation of the phenoxyl radical. However, in the case of TBL, the transformation of the phenoxyl radical into benzoquinone was impossible. Instead, the addition of OSO3H on the aromatic ring was the major pathway. The same reactivity pattern was observed in the case of TBL structural analogs resorcinol and 3,5-dihydroxybenzyl alcohol. Our results revealed that basic conditions inhibited the decomposition of SAL and TBL, while, increasing PS dose enhanced the degradation. The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters.
Axel Rosenhahn - One of the best experts on this subject based on the ideXlab platform.
-
Low-Fouling Thin Hydrogel Coatings Made of Photo-Cross-Linked Polyzwitterions
Langmuir, 2018Co-Authors: Julian Koc, Eric Schönemann, Ajitha Amuthalingam, Jessica L. Clarke, André Laschewsky, John A. Finlay, Anthony S. Clare, Axel RosenhahnAbstract:Although zwitterionic chemistries are among the most promising materials for producing non-fouling surfaces, their structural diversity has been small up to now. Here, we compare the in vitro fouling behavior of a set of four systematically varied sulfa-/sulfobetaine-containing zwitterionic hydrogel coatings against a series of proteins and non-motile as well as motile marine organisms as model foulers. The coatings are prepared by simultaneous photo-induced crosslinking and surface anchoring, to elucidate the effect of the molecular structure of the zwitterionic moieties on their antifouling activity. Analogously prepared coatings of poly(butylmethacrylate) and poly(oligoethylene glycol methacrylate) serve as references. Photo-reactive polymers are synthesized by statistical copolymerization of sulfobetaine or sulfabetaine methacrylates and methacrylamides with a Benzophenone Derivative of 2-hydroxyethylmethacrylate and applied as thin film coating. While keeping the density of the zwitterionic and of th...