The Experts below are selected from a list of 75 Experts worldwide ranked by ideXlab platform

Shayan Sharif - One of the best experts on this subject based on the ideXlab platform.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC Research Notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Objective Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Results Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC research notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

Jake Astill - One of the best experts on this subject based on the ideXlab platform.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC Research Notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Objective Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Results Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC research notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

Seizo Okamura - One of the best experts on this subject based on the ideXlab platform.

  • Structure of polymers formed by radiation‐induced solid‐phase polymerization of cyclic monomers
    Journal of Polymer Science Part C: Polymer Symposia, 2007
    Co-Authors: Koichiro Hayashi, M. Nishii, Seizo Okamura
    Abstract:

    The structure of polymer obtained by gamma -radiationinduced solid- state polymerization was examined by x-ray diffraction analysis. The polymers of 3,3-bischloromethylcycloxabutane, trioxane, and tetraoxane were shown to have an oriented mosaic structure of twin crystallites, of which two polymers of oxymethylene were in helical configuration. The polymer of BETA -propiolactone was not in the twin crystal form. Two kinds of polymers obtained from BETA - propiolactone and 3,3-bischloromethylcycloxabutane were found to be in planar zigzag configuration. (auth)

Alexander Yitbarek - One of the best experts on this subject based on the ideXlab platform.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC Research Notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Objective Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Results Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC research notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

Khaled Taha-abdelaziz - One of the best experts on this subject based on the ideXlab platform.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC Research Notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Objective Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Results Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.

  • Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine
    BMC research notes, 2018
    Co-Authors: Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-abdelaziz, Jegarubee Bavananthasivam, Éva Nagy, James John Petrik, Shayan Sharif
    Abstract:

    Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 Beta-Propiolactone inactivated virus vaccine to chickens. Given the fact that in ovo vaccination represents a practical option for vaccination against H9N2 AIV in chickens, in the current study, we set out to characterize immune responses in chickens against a Beta-Propiolactone inactivated H9N2 virus vaccine after primary vaccination in ovo on embryonic day 18, and secondary intramuscular vaccination on day 14 post-hatch. We also included the Toll-like receptor 21 ligand, CpG ODN 2007, and an oil emulsion adjuvant, AddaVax™, as adjuvants for the vaccines. Antibody-mediated immune responses were observed after administering the secondary intramuscular vaccine. Cell-mediated immune responses were observed in chickens that received the Beta-Propiolactone inactivated H9N2 virus combined with AddaVax™. Our results demonstrate that adaptive immune responses can be induced in chickens after a primary in ovo vaccination and secondary intramuscular vaccination.