Bile Leakage

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T M Van Gulik - One of the best experts on this subject based on the ideXlab platform.

E A J Rauws - One of the best experts on this subject based on the ideXlab platform.

  • incidence and management of Bile Leakage after partial liver resection
    Digestive Surgery, 2008
    Co-Authors: Deha Erdogan, E A J Rauws, O R C Busch, O M Van Delden, D J Gouma, T M Van Gulik
    Abstract:

    Background/Aims: Bile Leakage after partial liver resection still is a common complication and is associated with substantial morbidity and even mortality. Methods:

  • postoperative Bile Leakage endoscopic management
    Gut, 1992
    Co-Authors: P H P Davids, E A J Rauws, G N J Tytgat, K Huibregtse
    Abstract:

    Bile Leakage is an infrequent but serious complication after biliary tract surgery. This non-randomised single centre study evaluated the endoscopic management of this problem in 55 consecutive cases. Treatment consisted of standard sphincterotomy and, if needed, subsequent stone extraction with or without endoprosthesis placement. The aim of all treatments was to facilitate Bile flow into the duodenum. The biliary tract and the site of the Leakage were visualised during endoscopic retrograde cholangiopancreatography (ERCP) in 98%. There was distal obstruction in 33--caused by retained gall stones in 15 patients and concomitant strictures in 18. Overall, 48 of 55 patients were treated endoscopically. An excellent outcome (clinical and radiological resolution of the Bile leak) was achieved in 43 patients (90%). Five patients (10%) had continuing sepsis from which they died. Postoperative Bile Leakage can be diagnosed safely and effectively by ERCP and subsequent endoscopic management is successful in most cases.

Masatoshi Makuuchi - One of the best experts on this subject based on the ideXlab platform.

  • randomized trial of the usefulness of a Bile Leakage test during hepatic resection
    Archives of Surgery, 2000
    Co-Authors: Masayoshi Ijichi, Tadatoshi Takayama, Hiroyuki Toyoda, Keiji Sano, Keiichi Kubota, Masatoshi Makuuchi
    Abstract:

    Hypothesis An intraoperative Bile Leakage test will assist in decreasing postoperative Bile Leakage in patients undergoing hepatic resection. Design Randomized controlled trial. Setting University hospital. Patients One hundred three consecutive patients who were scheduled for hepatic resection without biliary reconstruction. Associated cirrhosis was present in 49 patients (48%), and only 24 (23%) had normal livers. Patients were randomized to undergo (n = 51) or to not undergo (n = 52) a Bile Leakage test, according to age, liver function, and hepatectomy method. The 2 groups were similar in baseline demographics. Intervention A Bile Leakage test was carried out by injecting isotonic sodium chloride solution through the cystic duct, and interrupted suturing was taken for a Bile leak on the transected liver surface. Main Outcome Measures The incidence of postoperative Bile Leakage and the length of the postoperative hospital stay. Bile Leakage was defined as continuous drainage, with a bilirubin level of 86 µmol/L or more (≥5 mg/dL), beyond 1 week. Results Twenty-one patients (41%) in the test group showed a Bile leak, and a median of 1 site (range, 1-6 sites) was closed during the test. Postoperative Bile Leakage was observed in 3 patients (6%) in the test group and in 2 (4%) in the control group ( P = .99). The odds ratio of the event was 1.53 (95% confidence interval, 0.25-9.44). The median postoperative hospital stay lasted 17 (range, 13-47) and 18 (range, 12-41) days for the test and control groups, respectively ( P = .98). Conclusion This randomized trial suggested no advantage in using a Bile Leakage test during hepatic resection.

Deha Erdogan - One of the best experts on this subject based on the ideXlab platform.

Hiroyuki Kuwano - One of the best experts on this subject based on the ideXlab platform.

  • in situ dye injection Bile Leakage test of the graft in living donor liver transplantation
    Transplantation, 2005
    Co-Authors: Taketoshi Suehiro, Mitsuo Shimada, Keiji Kishikawa, Tatsuo Shimura, Yuji Soejima, Tomoharu Yoshizumi, Kohji Hashimoto, Yasushi Mochida, Yoshihiko Maehara, Hiroyuki Kuwano
    Abstract:

    Background. Bile Leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ Leakage testing of the cut surface of grafts in LDLT. Methods. A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection Leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of Bile Leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables. Results. Bile Leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of Bile Leakage (22.5%). On the other hand, there was only one case (2.5%) of Bile Leakage in the test group (P<0.05). The Bile Leakage case in the test group was resolved preservationally. However, 2 of the 9 (22.2%) Bile Leakage cases in the control group required surgery. Conclusion. Although there is biliary complication, especially Bile Leakage from the cut surface, as an inevitable consequence of LDLT, this study suggests that there is advantage in conducting Bile Leakage testing to minimize the incidence of Bile Leakage from the cut surface, which is associated with a high risk of graft failure.

  • In situ dye injection Bile Leakage test of the graft in living donor liver transplantation.
    Transplantation, 2005
    Co-Authors: Taketoshi Suehiro, Mitsuo Shimada, Keiji Kishikawa, Tatsuo Shimura, Yuji Soejima, Tomoharu Yoshizumi, Kohji Hashimoto, Yasushi Mochida, Yoshihiko Maehara, Hiroyuki Kuwano
    Abstract:

    Background. Bile Leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ Leakage testing of the cut surface of grafts in LDLT. Methods. A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection Leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of Bile Leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables. Results. Bile Leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of Bile Leakage (22.5%). On the other hand, there was only one case (2.5%) of Bile Leakage in the test group (P